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The map label for this gene is sitD [H]

Identifier: 238896201

GI number: 238896201

Start: 4174019

End: 4174873

Strand: Direct

Name: sitD [H]

Synonym: KP1_4350

Alternate gene names: 238896201

Gene position: 4174019-4174873 (Clockwise)

Preceding gene: 238896200

Following gene: 238896204

Centisome position: 79.53

GC content: 59.06

Gene sequence:

>855_bases
ATGCTGAACCTGTTCCTGGCCCCGTTCCAGTTTCCTTTTATGGTCAATGCGATAGCGATATCGATCGTCGTCGCCATTCC
CTGCGCGCTGCTGTCGGTGTTTCTGGTGCTCAAAGGCTGGGCGCTGATGGGCGACGCCATGAGCCACGCGGTCTTTCCGG
GCGTGGTGCTGGCCTACATTATCGGCATCCCCTTCGCCATCGGCGCGTTTATCGCCGGTCTGCTGTGCGCCGTGACGACC
GGTTTTCTCGACGATAACAGCCGACTCAAGCGCGATACCATCATGGGGATTGTCTTCTCCGGCATGTTTGGCGCCGGACT
GGTGCTGTACGTAGCGATCCAGTCCGATGTTCATCTCGACCATATCCTGTTCGGCGATATGCTGGGAATATCCCTCCGCG
ATATTGGGCAAACGACGGCGATCGCACTGGTGATTGCGTTGATTATCGGTCTCAAATGGCGGGATTTTTTGCTGCACGCC
TTCGATCCAACGCAGGCTAAAGCCAGCGGCCTGCGCGGCGGACTGCTGCACTACGGCCTGCTGTGCATGATCGCCCTGAC
CATCGTCGCGACGCTGCAGTCGGTGGGGATTATTCTGTCGATTTCGCTGCTGATTGCCCCCGGGGCGATCGCGCTTCTGC
TGGTGAGACGCTTTATCCACGCCCTGCTGCTGGCGGTAGCGGTGGCCATCGGCTGCTCGGCGGGAGGGGTGTGGCTGGCG
TTTTATCTCGACAGCGCGCCAGCGCCGACTATCGTGGTGCTGTTTACCGCGCTGTTTGTAGTCGCCTTTGTCGCAAGCAC
GATCCGCGATAGTCAGAAACAGAAAACTTCAGCAATTATCCCCGGTGGCGGCTAA

Upstream 100 bases:

>100_bases
GCATTATCGTGGTCGCGCAAACGCTGCTGTTCCTCATCACCTTTATCTTCGCGCCGAAGCACGGCCTGCTGGCCAGCCGC
CGCCGCGCCAGGGAGGCCGC

Downstream 100 bases:

>100_bases
CGCCTTGCCGGGGCTACAAGAGCACGACTTGTCGCCCGGCTGCGCAGCGCTGACCAGGGAAAGCCGCTACTTTTTCGGTC
GATATTTTTCCGGCAGCGGC

Product: iron transport system permease component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MLNLFLAPFQFPFMVNAIAISIVVAIPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAYIIGIPFAIGAFIAGLLCAVTT
GFLDDNSRLKRDTIMGIVFSGMFGAGLVLYVAIQSDVHLDHILFGDMLGISLRDIGQTTAIALVIALIIGLKWRDFLLHA
FDPTQAKASGLRGGLLHYGLLCMIALTIVATLQSVGIILSISLLIAPGAIALLLVRRFIHALLLAVAVAIGCSAGGVWLA
FYLDSAPAPTIVVLFTALFVVAFVASTIRDSQKQKTSAIIPGGG

Sequences:

>Translated_284_residues
MLNLFLAPFQFPFMVNAIAISIVVAIPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAYIIGIPFAIGAFIAGLLCAVTT
GFLDDNSRLKRDTIMGIVFSGMFGAGLVLYVAIQSDVHLDHILFGDMLGISLRDIGQTTAIALVIALIIGLKWRDFLLHA
FDPTQAKASGLRGGLLHYGLLCMIALTIVATLQSVGIILSISLLIAPGAIALLLVRRFIHALLLAVAVAIGCSAGGVWLA
FYLDSAPAPTIVVLFTALFVVAFVASTIRDSQKQKTSAIIPGGG
>Mature_284_residues
MLNLFLAPFQFPFMVNAIAISIVVAIPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAYIIGIPFAIGAFIAGLLCAVTT
GFLDDNSRLKRDTIMGIVFSGMFGAGLVLYVAIQSDVHLDHILFGDMLGISLRDIGQTTAIALVIALIIGLKWRDFLLHA
FDPTQAKASGLRGGLLHYGLLCMIALTIVATLQSVGIILSISLLIAPGAIALLLVRRFIHALLLAVAVAIGCSAGGVWLA
FYLDSAPAPTIVVLFTALFVVAFVASTIRDSQKQKTSAIIPGGG

Specific function: Part of an ATP-driven transport system yfeABCD for chelated iron [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=256, Percent_Identity=27.734375, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 29847; Mature: 29847

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLFLAPFQFPFMVNAIAISIVVAIPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAYI
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIPFAIGAFIAGLLCAVTTGFLDDNSRLKRDTIMGIVFSGMFGAGLVLYVAIQSDVHLD
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCHH
HILFGDMLGISLRDIGQTTAIALVIALIIGLKWRDFLLHAFDPTQAKASGLRGGLLHYGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHH
LCMIALTIVATLQSVGIILSISLLIAPGAIALLLVRRFIHALLLAVAVAIGCSAGGVWLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FYLDSAPAPTIVVLFTALFVVAFVASTIRDSQKQKTSAIIPGGG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLNLFLAPFQFPFMVNAIAISIVVAIPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAYI
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIPFAIGAFIAGLLCAVTTGFLDDNSRLKRDTIMGIVFSGMFGAGLVLYVAIQSDVHLD
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCHH
HILFGDMLGISLRDIGQTTAIALVIALIIGLKWRDFLLHAFDPTQAKASGLRGGLLHYGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHH
LCMIALTIVATLQSVGIILSISLLIAPGAIALLLVRRFIHALLLAVAVAIGCSAGGVWLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FYLDSAPAPTIVVLFTALFVVAFVASTIRDSQKQKTSAIIPGGG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9495751; 11586360; 12142430 [H]