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The map label for this gene is gmuD [H]

Identifier: 238896189

GI number: 238896189

Start: 4160593

End: 4161993

Strand: Reverse

Name: gmuD [H]

Synonym: KP1_4337

Alternate gene names: 238896189

Gene position: 4161993-4160593 (Counterclockwise)

Preceding gene: 238896190

Following gene: 238896182

Centisome position: 79.3

GC content: 55.96

Gene sequence:

>1401_bases
ATGCAGCAGTATCAGTTTCCGCAAGGGTTCCTGTGGGGGGCGGCGGCGTCCGGCCCGCAAACGGAAGGGGTCACCAATAA
GCGCCATCGTTCCATCTGGGACAGTTGGTTTGCCGAACAGCCGGAGCGATTTTATCAGCAGGTAGGGCCGCAGACCGTGT
GTGATACTTATCATCAGTATCCGCAGGACGTAGCGCTGATGAAACAGACCGGCTTCAACTCATTTCGTACCTCGATACAG
TGGTCACGACTGATCGCTGATTTGGAAACCGGCGCGCCGGACCCGGACGCGGTGCGTTTTTATCACGCCTATCTGGATGA
GATGATCGCCAACGGCATTGAGCCGATGATCAATCTCTACCACTTTGATATGCCGGAAGCGCTGCAGAAACAGTACGGCG
GCTTTGAATCGGCGCACGTAGCCGAGCTGTTTGCCCGCTTTGCCCGCACCGCCTTTAGCCTGTTTGGCCATAAGGTTAAA
TACTGGATAACCTTCAACGAGCCGATTGTGCCGGTTGAGGGAGGCTACCTGTACGACTTCCACTATCCATGTAAGAAAGA
TGGCCGGCTGGCGGCGCAGGTGGCGTTTAACATTATGCTGGCGCACGCCAAAGCGGTAACGGCTTATCGTGAACTGGCGC
TGGCGGGCGAGATCGGCGTGGTGCTCAACCTGACCCCGAGCTATACCCTCACCGACAGCGACGCGGATAAAAAAGCCGCC
GGGTATGCCGACCTGTTTTTTAACCGCAGCTTCCTTGACCCGCTGGTAAAACATGAATTCCCCAAAGCGCTGTGCGAGAT
CCTTGCCGCCCACGACTGCCTGCCGACGACCAGCAAAGACGACGCGGCGTTGATCCTCAGCGCGGATATCGATTTTCTTG
GGGTAAACTATTACGTGCCGCGGCGGGTAAAAGCGCGTGAGAGCGAATATGACCTCGATTATTTCACCCCGGAATACTAT
TTCGAAAACGCGGTGAACCCGCAGGGCCGCTTTAATCCTTATCGTGATAACAACGAGATCCTGCCGCAGGCGATCTATGA
CATTGCCGCCAATATTCGCGATAACTACGGCAATATTAAGTGGTATCTCGCGGAAATCGGCATCGCGATGGATCGACAAT
CAGAGGGCGAGCCCGGGGCGGACGGGGTGATAGACGATACTTTCCGCATCCAGCTGATGGAGGAGCATCTGGTGCAGCTG
CATCGGGCGATAGCCGACGGCGCGAACTGCTTTGGCGTGCACCAGTGGACGTTTATCGACAACTGGTCGTGGATCAATGC
CTTCAAACGGCGCTACGGCTTCTGGCGACTGGATCTGGAGACCGGCGAGCGACAGATAAAACGCAATGCGCTGTGGTTTG
CCGAACTGGCGTCCAGCAACGGTTTTACCAGCGATAAATAG

Upstream 100 bases:

>100_bases
GCGACTGGGGCTATATGTTCATTAAATCGATCGAAGTGGTCGCTGAGTAGTACGTTCAGGCTGCGCCAGACGGGCGCAGC
CTTTTTTCGAAGGAGAGGTT

Downstream 100 bases:

>100_bases
CGCGCTGCGCCAGCGCTCCCTCTCTCCGGCGCGGAAAGGGGGAGCGCGCGAGGTTACACCAGTTCGTCTTTATTAATACC
CAGCCGCTTCATGCGTGACA

Product: phospho-beta-glucosidase B

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MQQYQFPQGFLWGAAASGPQTEGVTNKRHRSIWDSWFAEQPERFYQQVGPQTVCDTYHQYPQDVALMKQTGFNSFRTSIQ
WSRLIADLETGAPDPDAVRFYHAYLDEMIANGIEPMINLYHFDMPEALQKQYGGFESAHVAELFARFARTAFSLFGHKVK
YWITFNEPIVPVEGGYLYDFHYPCKKDGRLAAQVAFNIMLAHAKAVTAYRELALAGEIGVVLNLTPSYTLTDSDADKKAA
GYADLFFNRSFLDPLVKHEFPKALCEILAAHDCLPTTSKDDAALILSADIDFLGVNYYVPRRVKARESEYDLDYFTPEYY
FENAVNPQGRFNPYRDNNEILPQAIYDIAANIRDNYGNIKWYLAEIGIAMDRQSEGEPGADGVIDDTFRIQLMEEHLVQL
HRAIADGANCFGVHQWTFIDNWSWINAFKRRYGFWRLDLETGERQIKRNALWFAELASSNGFTSDK

Sequences:

>Translated_466_residues
MQQYQFPQGFLWGAAASGPQTEGVTNKRHRSIWDSWFAEQPERFYQQVGPQTVCDTYHQYPQDVALMKQTGFNSFRTSIQ
WSRLIADLETGAPDPDAVRFYHAYLDEMIANGIEPMINLYHFDMPEALQKQYGGFESAHVAELFARFARTAFSLFGHKVK
YWITFNEPIVPVEGGYLYDFHYPCKKDGRLAAQVAFNIMLAHAKAVTAYRELALAGEIGVVLNLTPSYTLTDSDADKKAA
GYADLFFNRSFLDPLVKHEFPKALCEILAAHDCLPTTSKDDAALILSADIDFLGVNYYVPRRVKARESEYDLDYFTPEYY
FENAVNPQGRFNPYRDNNEILPQAIYDIAANIRDNYGNIKWYLAEIGIAMDRQSEGEPGADGVIDDTFRIQLMEEHLVQL
HRAIADGANCFGVHQWTFIDNWSWINAFKRRYGFWRLDLETGERQIKRNALWFAELASSNGFTSDK
>Mature_466_residues
MQQYQFPQGFLWGAAASGPQTEGVTNKRHRSIWDSWFAEQPERFYQQVGPQTVCDTYHQYPQDVALMKQTGFNSFRTSIQ
WSRLIADLETGAPDPDAVRFYHAYLDEMIANGIEPMINLYHFDMPEALQKQYGGFESAHVAELFARFARTAFSLFGHKVK
YWITFNEPIVPVEGGYLYDFHYPCKKDGRLAAQVAFNIMLAHAKAVTAYRELALAGEIGVVLNLTPSYTLTDSDADKKAA
GYADLFFNRSFLDPLVKHEFPKALCEILAAHDCLPTTSKDDAALILSADIDFLGVNYYVPRRVKARESEYDLDYFTPEYY
FENAVNPQGRFNPYRDNNEILPQAIYDIAANIRDNYGNIKWYLAEIGIAMDRQSEGEPGADGVIDDTFRIQLMEEHLVQL
HRAIADGANCFGVHQWTFIDNWSWINAFKRRYGFWRLDLETGERQIKRNALWFAELASSNGFTSDK

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=456, Percent_Identity=28.0701754385965, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI110681710, Length=495, Percent_Identity=25.4545454545455, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI32481206, Length=483, Percent_Identity=27.1221532091097, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24497614, Length=486, Percent_Identity=24.0740740740741, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI28376633, Length=204, Percent_Identity=32.843137254902, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI2367270, Length=493, Percent_Identity=29.2089249492901, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI2367174, Length=494, Percent_Identity=28.1376518218623, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1789070, Length=484, Percent_Identity=28.5123966942149, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17539390, Length=464, Percent_Identity=29.7413793103448, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17552856, Length=480, Percent_Identity=28.125, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI21356577, Length=483, Percent_Identity=27.1221532091097, Blast_Score=178, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53421; Mature: 53421

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQYQFPQGFLWGAAASGPQTEGVTNKRHRSIWDSWFAEQPERFYQQVGPQTVCDTYHQY
CCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHC
PQDVALMKQTGFNSFRTSIQWSRLIADLETGAPDPDAVRFYHAYLDEMIANGIEPMINLY
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
HFDMPEALQKQYGGFESAHVAELFARFARTAFSLFGHKVKYWITFNEPIVPVEGGYLYDF
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCCCEEEEE
HYPCKKDGRLAAQVAFNIMLAHAKAVTAYRELALAGEIGVVLNLTPSYTLTDSDADKKAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCHHHC
GYADLFFNRSFLDPLVKHEFPKALCEILAAHDCLPTTSKDDAALILSADIDFLGVNYYVP
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECCEECC
RRVKARESEYDLDYFTPEYYFENAVNPQGRFNPYRDNNEILPQAIYDIAANIRDNYGNIK
CCHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
WYLAEIGIAMDRQSEGEPGADGVIDDTFRIQLMEEHLVQLHRAIADGANCFGVHQWTFID
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
NWSWINAFKRRYGFWRLDLETGERQIKRNALWFAELASSNGFTSDK
CCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQQYQFPQGFLWGAAASGPQTEGVTNKRHRSIWDSWFAEQPERFYQQVGPQTVCDTYHQY
CCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHC
PQDVALMKQTGFNSFRTSIQWSRLIADLETGAPDPDAVRFYHAYLDEMIANGIEPMINLY
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
HFDMPEALQKQYGGFESAHVAELFARFARTAFSLFGHKVKYWITFNEPIVPVEGGYLYDF
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCCCEEEEE
HYPCKKDGRLAAQVAFNIMLAHAKAVTAYRELALAGEIGVVLNLTPSYTLTDSDADKKAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCHHHC
GYADLFFNRSFLDPLVKHEFPKALCEILAAHDCLPTTSKDDAALILSADIDFLGVNYYVP
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECCEECC
RRVKARESEYDLDYFTPEYYFENAVNPQGRFNPYRDNNEILPQAIYDIAANIRDNYGNIK
CCHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
WYLAEIGIAMDRQSEGEPGADGVIDDTFRIQLMEEHLVQLHRAIADGANCFGVHQWTFID
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
NWSWINAFKRRYGFWRLDLETGERQIKRNALWFAELASSNGFTSDK
CCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]