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The map label for this gene is hycA [H]

Identifier: 238896182

GI number: 238896182

Start: 4153960

End: 4154409

Strand: Reverse

Name: hycA [H]

Synonym: KP1_4329

Alternate gene names: 238896182

Gene position: 4154409-4153960 (Counterclockwise)

Preceding gene: 238896189

Following gene: 238896181

Centisome position: 79.15

GC content: 56.44

Gene sequence:

>450_bases
ATGACTATTTGGGAAATAAGTGAAAAGGCGGATTACATCGCCGACCGTCACCGGCAGCAGCAGGAGCAGTGGCACATCTA
CTGTAACTCGCTGGTTCAGGGGATCACCTTGTCGAAGGCCCGCCTGCATCACGCGATGAGCTGCGCGCCGGACAAAGAGC
TGTGCTTCGTGCTGTTCGGCCATTTTCAGGTGTTCGTCGCCCTCGCGGAAGGCTTCAACAGCCACACCATTGAGTACTAC
GTCGAAAACAAAAACGGCGGTGATAAGTATCTGATTGCTCAGGCCACCCTCGCAATGGATGGCACGGTGGACGGCCGCAT
CAGCAACCGCTCCCGCGACCAGGTGCTGGAGCACTATCTGGCGATTATCGCCACCGTCTATGACCGTCTGTATGACGCCA
TGGAACAAGACCAACCGGTGGATTTAAGCCATCTGGCGCTGACCCACTGA

Upstream 100 bases:

>100_bases
CATCGGCAGAGTTCGATACAAAAACATAGTAAAATCAATTAAATAAAATCTGGTATGAAAAATGCTTAGAGGGTGCATCT
CATGCTACGGAGAAACCGAT

Downstream 100 bases:

>100_bases
TCGTAAGGTGTCGACACGTGTCGAAAATGACACCTGCGCAACCTGATTTCGTCAAAAATGACTTTCACCCGAGGATGACC
CGGTGAACCGTTTTGTAATT

Product: formate hydrogenlyase regulatory protein HycA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTIWEISEKADYIADRHRQQQEQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFGHFQVFVALAEGFNSHTIEYY
VENKNGGDKYLIAQATLAMDGTVDGRISNRSRDQVLEHYLAIIATVYDRLYDAMEQDQPVDLSHLALTH

Sequences:

>Translated_149_residues
MTIWEISEKADYIADRHRQQQEQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFGHFQVFVALAEGFNSHTIEYY
VENKNGGDKYLIAQATLAMDGTVDGRISNRSRDQVLEHYLAIIATVYDRLYDAMEQDQPVDLSHLALTH
>Mature_148_residues
TIWEISEKADYIADRHRQQQEQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFGHFQVFVALAEGFNSHTIEYYV
ENKNGGDKYLIAQATLAMDGTVDGRISNRSRDQVLEHYLAIIATVYDRLYDAMEQDQPVDLSHLALTH

Specific function: Regulatory protein for the formate hydrogenlyase system. Could act by directly interacting with fhlA or by preventing the binding of fhlA to the upstream activatory sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789080, Length=145, Percent_Identity=74.4827586206897, Blast_Score=233, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021285 [H]

Pfam domain/function: PF11046 HycA_repressor [H]

EC number: NA

Molecular weight: Translated: 17115; Mature: 16984

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIWEISEKADYIADRHRQQQEQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFG
CCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HFQVFVALAEGFNSHTIEYYVENKNGGDKYLIAQATLAMDGTVDGRISNRSRDQVLEHYL
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
AIIATVYDRLYDAMEQDQPVDLSHLALTH
HHHHHHHHHHHHHHHCCCCCCHHHHEECC
>Mature Secondary Structure 
TIWEISEKADYIADRHRQQQEQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFG
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HFQVFVALAEGFNSHTIEYYVENKNGGDKYLIAQATLAMDGTVDGRISNRSRDQVLEHYL
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
AIIATVYDRLYDAMEQDQPVDLSHLALTH
HHHHHHHHHHHHHHHCCCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]