Click here to switch to the map view.

The map label for this gene is emrR [H]

Identifier: 238896137

GI number: 238896137

Start: 4107486

End: 4107986

Strand: Direct

Name: emrR [H]

Synonym: KP1_4277

Alternate gene names: 238896137

Gene position: 4107486-4107986 (Clockwise)

Preceding gene: 238896136

Following gene: 238896138

Centisome position: 78.26

GC content: 52.69

Gene sequence:

>501_bases
ATGCTCAAGTTCCGCGCCAGCCGCCATGAAGATTTCCCGTTTCAGGAGATCCTGTTAACTCGTCTTTGCATGCATATGCA
AGGTAAGCTGCTGGAAAATCGCAATAAAATGCTCAAAGCGCAGGGAATTAACGAGACATTATTTATGGCGCTGATTACGC
TGGAGTCACAGGAAAACCACAGCATCCAGCCGTCCGAGCTGAGCTGTGCGCTGGGCTCGTCACGTACCAACGCCACCCGT
ATCGCTGATGAACTGGAAAAACGCGGCTGGATTGAGCGCCGCGAGAGCGATAACGATCGTCGCTGTTTGCATCTGCAACT
GACCGAAAAGGGCCATCAGTTTTTGCGTGAAGTCCTGCCGCCGCAGCATAACTGCCTGCATCAGCTGTGGTCTTCACTTA
GCACCAGCGAAAAAGATCAGCTCGAACACATCACCCGCAAACTCCTGAGCCGCCTTGATCAGATGGAAGAAGAAGGCGTG
CTAGCGGACTCTCTACGCTAA

Upstream 100 bases:

>100_bases
TCAATAATTCATTTGATTTATTTGTCACAATAGTTATTATATCGGCTGTAATTAATGAGGTCATACCCAAATGGATAGTT
CGTTTACTCCCATTGAGCAA

Downstream 100 bases:

>100_bases
GGGCGGCGTCGCTCAGCCCATTTTTACGTTGCAAGGAAAACAGCCAGGCCAGCAGATCTCTGCTGGCCTTTCTGATAAAC
AGGTCGGCTCAGCCGATGTG

Product: transcriptional repressor MprA

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MLKFRASRHEDFPFQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATR
IADELEKRGWIERRESDNDRRCLHLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGV
LADSLR

Sequences:

>Translated_166_residues
MLKFRASRHEDFPFQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATR
IADELEKRGWIERRESDNDRRCLHLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGV
LADSLR
>Mature_166_residues
MLKFRASRHEDFPFQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATR
IADELEKRGWIERRESDNDRRCLHLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGV
LADSLR

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=165, Percent_Identity=92.1212121212121, Blast_Score=318, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 19432; Mature: 19432

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFRASRHEDFPFQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
SIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGHQFLREVLP
CCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEHHHHHHHHHHHCC
PQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGVLADSLR
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MLKFRASRHEDFPFQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
SIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGHQFLREVLP
CCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEHHHHHHHHHHHCC
PQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGVLADSLR
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]