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The map label for this gene is pheC [H]

Identifier: 238896103

GI number: 238896103

Start: 4073801

End: 4074649

Strand: Reverse

Name: pheC [H]

Synonym: KP1_4242

Alternate gene names: 238896103

Gene position: 4074649-4073801 (Counterclockwise)

Preceding gene: 238896109

Following gene: 238896093

Centisome position: 77.63

GC content: 58.66

Gene sequence:

>849_bases
ATGAATGCCCTGGCTCGCGCGGCGGATACTGTGACTGATGCGGCCGGTCACTCTGGCATGAAAACCGATAACTTTAAGGA
TGGCGAAATGAGACTGACGGTGGGGCTGGCGCTGACGCTGGCGATAATGACCTGCGGCGCCCAGGCGCGCGATATGCAAT
CCATCGAGCACAGCGGTGAACTGAAGGTGGGCGTGCCGGGCGATTACGCGCCGCTGGCGTTTCGCAATGCCGCCGGCGAA
CTGCAGGGCTATGACGTGGACATGGCCCGCGATCTCGGGCGCACGCTCGGGCTGAAGGTGAGCTTCGTCTACACCAGCTG
GCCCGCGCTCGCCGCCGATCTGCAGGCGGACAAGTTTGATATTGCGATGGGTGGGGTTACCGAGACCCCGGCGCGCGCGC
AAGCCTTCGCCCTCAGCCATCCGGTGGTGGCGAACGGAAAAATCGCCTTAGCCAACTGCCAGGCCGCCCCGCGGCTCGGT
TCGCTGGAAAAAATTGACCGTCCGGACGTGAAAGTGATCGTCAACCCTGGCGGCACAAATCAGAGTTTTGTCGATGAACA
CATCAAGCAGGCGCAAATTATTCGCGTGCAGAACAATGTCGATAACCTGCAGGCGCTGCGGCAGAAAACGGCCGATATGA
TGGTGACCGATCTGATTGAAGGCGACTATTACCAGAGCAAAGAGCCCGGCGTGTTCTGCGTTGCTAACGAAACACCGTTC
GCCGGTACCGCCAGCAACAAGGTGTATATGATGAGTAAAGATAACCCGGCGCTGCTGGAGAAAGTGAACCAGTGGCTGGA
TAGCCAGGACAAAGAGGTTCTCAAACGGAAGTGGAAAATTCGCGGTTAA

Upstream 100 bases:

>100_bases
TTACTGAAAGTCAAAACAACCAGCAAGCTCACAGCGAGAAAGAGGATTAATTAACGTTTTGCCCCACGTCGGGTTGTATG
TCCCGGTGTTTAAAAATAGG

Downstream 100 bases:

>100_bases
CCGCGGCGGCGCGCCACCGCCGGCAGACACGCCCGGCGGTGGCTATCGTCCACGGTTAGCGCTGCGACGACAGGGCCTGT
CGCGCCAGACCGCGGAAGTA

Product: putative ABC-type amino acid transport/signal transduction systems periplasmic component

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNALARAADTVTDAAGHSGMKTDNFKDGEMRLTVGLALTLAIMTCGAQARDMQSIEHSGELKVGVPGDYAPLAFRNAAGE
LQGYDVDMARDLGRTLGLKVSFVYTSWPALAADLQADKFDIAMGGVTETPARAQAFALSHPVVANGKIALANCQAAPRLG
SLEKIDRPDVKVIVNPGGTNQSFVDEHIKQAQIIRVQNNVDNLQALRQKTADMMVTDLIEGDYYQSKEPGVFCVANETPF
AGTASNKVYMMSKDNPALLEKVNQWLDSQDKEVLKRKWKIRG

Sequences:

>Translated_282_residues
MNALARAADTVTDAAGHSGMKTDNFKDGEMRLTVGLALTLAIMTCGAQARDMQSIEHSGELKVGVPGDYAPLAFRNAAGE
LQGYDVDMARDLGRTLGLKVSFVYTSWPALAADLQADKFDIAMGGVTETPARAQAFALSHPVVANGKIALANCQAAPRLG
SLEKIDRPDVKVIVNPGGTNQSFVDEHIKQAQIIRVQNNVDNLQALRQKTADMMVTDLIEGDYYQSKEPGVFCVANETPF
AGTASNKVYMMSKDNPALLEKVNQWLDSQDKEVLKRKWKIRG
>Mature_282_residues
MNALARAADTVTDAAGHSGMKTDNFKDGEMRLTVGLALTLAIMTCGAQARDMQSIEHSGELKVGVPGDYAPLAFRNAAGE
LQGYDVDMARDLGRTLGLKVSFVYTSWPALAADLQADKFDIAMGGVTETPARAQAFALSHPVVANGKIALANCQAAPRLG
SLEKIDRPDVKVIVNPGGTNQSFVDEHIKQAQIIRVQNNVDNLQALRQKTADMMVTDLIEGDYYQSKEPGVFCVANETPF
AGTASNKVYMMSKDNPALLEKVNQWLDSQDKEVLKRKWKIRG

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=235, Percent_Identity=24.2553191489362, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788648, Length=129, Percent_Identity=30.2325581395349, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 30558; Mature: 30558

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALARAADTVTDAAGHSGMKTDNFKDGEMRLTVGLALTLAIMTCGAQARDMQSIEHSGE
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHCCCC
LKVGVPGDYAPLAFRNAAGELQGYDVDMARDLGRTLGLKVSFVYTSWPALAADLQADKFD
EEECCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCEEEEEEEECCCHHHHHCCCCCEE
IAMGGVTETPARAQAFALSHPVVANGKIALANCQAAPRLGSLEKIDRPDVKVIVNPGGTN
EEECCCCCCCCHHHHEECCCCEEECCEEEEEECCCCCCCCCHHHCCCCCEEEEECCCCCC
QSFVDEHIKQAQIIRVQNNVDNLQALRQKTADMMVTDLIEGDYYQSKEPGVFCVANETPF
HHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
AGTASNKVYMMSKDNPALLEKVNQWLDSQDKEVLKRKWKIRG
CCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNALARAADTVTDAAGHSGMKTDNFKDGEMRLTVGLALTLAIMTCGAQARDMQSIEHSGE
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHCCCC
LKVGVPGDYAPLAFRNAAGELQGYDVDMARDLGRTLGLKVSFVYTSWPALAADLQADKFD
EEECCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCEEEEEEEECCCHHHHHCCCCCEE
IAMGGVTETPARAQAFALSHPVVANGKIALANCQAAPRLGSLEKIDRPDVKVIVNPGGTN
EEECCCCCCCCHHHHEECCCCEEECCEEEEEECCCCCCCCCHHHCCCCCEEEEECCCCCC
QSFVDEHIKQAQIIRVQNNVDNLQALRQKTADMMVTDLIEGDYYQSKEPGVFCVANETPF
HHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
AGTASNKVYMMSKDNPALLEKVNQWLDSQDKEVLKRKWKIRG
CCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]