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The map label for this gene is cfxR [H]

Identifier: 238896093

GI number: 238896093

Start: 4064158

End: 4065069

Strand: Reverse

Name: cfxR [H]

Synonym: KP1_4231

Alternate gene names: 238896093

Gene position: 4065069-4064158 (Counterclockwise)

Preceding gene: 238896103

Following gene: 238896090

Centisome position: 77.45

GC content: 59.65

Gene sequence:

>912_bases
ATGCATCACGACGCCAGCCTCAATATTCGCCAGCTGCAGGTTTTCGAGGCGGTGGCCCGCCTGGAGAGCTACAGCCGGGC
CCAGCAGGAGCTGGGTATTTCGGTCTCCGCCATCAGCAATGCCATGTCGCAGCTGGAGGGACAGCTCGGCTTCACCCTCT
GCCAGCGCGGGCGCGGCGGCTTTTCTCTGACCGAGAAAGGTCAGCAGTTTTTACAGCAGGCGATCCGCGTACTGAGCGAA
CTCAATGAGCTGGAGCGGCAGTCGGCGCTGCTCAAAGGGGAGCACAGCGGCACCCTGTGCATCTCGACGCTCGACTCCAT
CGAGACCGAAACGGCGCTCTCGCTGCCGGTGGTTCTGCGCAGCTTCAGCGACAAATTTCCCCATGTGCATATCAAACTGA
TTATCCGCACCCCGGCGGAGCAACAGAACGGCGTGCTGAACAACCATATCGACCTGGCTATCGGCAGCTACAACTCGCAG
GTGCATAACATCATCAGCGAGCCGCTGTACCGTGAACAGCACTGGCTCTACTGCAGCGATCTGCACCCGATGTTCTTCAG
CCGCCAGCTCGATAAAGAGCAGATCAGCCAGTGCCCGCTGGTGACCCGCAGCTACTGGAACACCAGCGATCTCCGCCGTC
GGGGCTTCAGCAAAGGGAGCGCCACCGTCGAGACCGTCGACGCCCAGCTGCTGCTGATCCTCTCGGGGAAATATATTGGC
TATCTGCCGGAGCATTACGCCTGGCCGTGGATCAAAGAGAACCGCCTGCGGGTGCTGCTGCCCAACGAGTTTGGCTTTCA
GTCGCCGTTCTCGGCCATCTGTAAGCGCGGGCGCAGCAATGAACCCTATCTGAAAGCGTTCCGCGATCTGCTGAAGAAAA
ATACGGTAGCGCGGCCGAAGTGGAATTATTAA

Upstream 100 bases:

>100_bases
TGACGGATGAAACGTAACAGGAGAGATAGTGCGCAACCCGCGCTGGACTTTACATCGTCTGGCGTAAATACTCAGTTCAT
TTATTGGTGAACTAAATACG

Downstream 100 bases:

>100_bases
GCGGGGCGGGCGCTTCCCTGTGCCTGGGTGGTGATTTTCGCGCTTAGCGCGCTGCCCGGCGGGGGAGTTTTCCCTGTTCA
AAAAACGAACGGCGGCCGGT

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: RuBisCO operon transcriptional regulator [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MHHDASLNIRQLQVFEAVARLESYSRAQQELGISVSAISNAMSQLEGQLGFTLCQRGRGGFSLTEKGQQFLQQAIRVLSE
LNELERQSALLKGEHSGTLCISTLDSIETETALSLPVVLRSFSDKFPHVHIKLIIRTPAEQQNGVLNNHIDLAIGSYNSQ
VHNIISEPLYREQHWLYCSDLHPMFFSRQLDKEQISQCPLVTRSYWNTSDLRRRGFSKGSATVETVDAQLLLILSGKYIG
YLPEHYAWPWIKENRLRVLLPNEFGFQSPFSAICKRGRSNEPYLKAFRDLLKKNTVARPKWNY

Sequences:

>Translated_303_residues
MHHDASLNIRQLQVFEAVARLESYSRAQQELGISVSAISNAMSQLEGQLGFTLCQRGRGGFSLTEKGQQFLQQAIRVLSE
LNELERQSALLKGEHSGTLCISTLDSIETETALSLPVVLRSFSDKFPHVHIKLIIRTPAEQQNGVLNNHIDLAIGSYNSQ
VHNIISEPLYREQHWLYCSDLHPMFFSRQLDKEQISQCPLVTRSYWNTSDLRRRGFSKGSATVETVDAQLLLILSGKYIG
YLPEHYAWPWIKENRLRVLLPNEFGFQSPFSAICKRGRSNEPYLKAFRDLLKKNTVARPKWNY
>Mature_303_residues
MHHDASLNIRQLQVFEAVARLESYSRAQQELGISVSAISNAMSQLEGQLGFTLCQRGRGGFSLTEKGQQFLQQAIRVLSE
LNELERQSALLKGEHSGTLCISTLDSIETETALSLPVVLRSFSDKFPHVHIKLIIRTPAEQQNGVLNNHIDLAIGSYNSQ
VHNIISEPLYREQHWLYCSDLHPMFFSRQLDKEQISQCPLVTRSYWNTSDLRRRGFSKGSATVETVDAQLLLILSGKYIG
YLPEHYAWPWIKENRLRVLLPNEFGFQSPFSAICKRGRSNEPYLKAFRDLLKKNTVARPKWNY

Specific function: Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=199, Percent_Identity=30.6532663316583, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786401, Length=305, Percent_Identity=24.9180327868852, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=225, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787530, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=283, Percent_Identity=23.6749116607774, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789173, Length=170, Percent_Identity=30, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081904, Length=251, Percent_Identity=25.8964143426295, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34635; Mature: 34635

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHDASLNIRQLQVFEAVARLESYSRAQQELGISVSAISNAMSQLEGQLGFTLCQRGRGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSLTEKGQQFLQQAIRVLSELNELERQSALLKGEHSGTLCISTLDSIETETALSLPVVLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
SFSDKFPHVHIKLIIRTPAEQQNGVLNNHIDLAIGSYNSQVHNIISEPLYREQHWLYCSD
HHHCCCCEEEEEEEEECCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEECC
LHPMFFSRQLDKEQISQCPLVTRSYWNTSDLRRRGFSKGSATVETVDAQLLLILSGKYIG
CCHHHHHHHCCHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCEEEHHHHEEEEEECCCHHC
YLPEHYAWPWIKENRLRVLLPNEFGFQSPFSAICKRGRSNEPYLKAFRDLLKKNTVARPK
CCCHHCCCCCEECCCEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
WNY
CCC
>Mature Secondary Structure
MHHDASLNIRQLQVFEAVARLESYSRAQQELGISVSAISNAMSQLEGQLGFTLCQRGRGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSLTEKGQQFLQQAIRVLSELNELERQSALLKGEHSGTLCISTLDSIETETALSLPVVLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
SFSDKFPHVHIKLIIRTPAEQQNGVLNNHIDLAIGSYNSQVHNIISEPLYREQHWLYCSD
HHHCCCCEEEEEEEEECCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEECC
LHPMFFSRQLDKEQISQCPLVTRSYWNTSDLRRRGFSKGSATVETVDAQLLLILSGKYIG
CCHHHHHHHCCHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCEEEHHHHEEEEEECCCHHC
YLPEHYAWPWIKENRLRVLLPNEFGFQSPFSAICKRGRSNEPYLKAFRDLLKKNTVARPK
CCCHHCCCCCEECCCEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
WNY
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1779759 [H]