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The map label for this gene is hcaT [H]

Identifier: 238895995

GI number: 238895995

Start: 3952285

End: 3953421

Strand: Reverse

Name: hcaT [H]

Synonym: KP1_4122

Alternate gene names: 238895995

Gene position: 3953421-3952285 (Counterclockwise)

Preceding gene: 238895996

Following gene: 238895993

Centisome position: 75.32

GC content: 62.53

Gene sequence:

>1137_bases
ATGGTCTTGCACTCCACGCGCTGGCTGGCGCTCAGTTATTTCACCTACTTTTTTAGCTACGGTATTTTTCTGCCCTTCTG
GAGCGTCTGGCTGGCTGGAAACGGGCTGACTCCGGAAACCATCGGCATTTTGCTTGGCGCCGGTCTGGTGGCCCGTTTTC
TCGGCAGTCTGCTGATTGCCCCGCGGGTGAGCGATCCCTCCCGGCTGATCGCCGCGCTGCGCGTGCTGGCGCTGTTAACC
TTGCTCTTCGCGCTGGCCTTCTGGGCCGGCAGCCACGTAGCATGGCTGCTGGCGATCATCATCGGCTTCAACCTGTTCTT
TTCGCCGCTGGTGCCGCTGACGGATGCTCTGGCCAATACCTGGCAAAAGCAGATCACCATGGACTATGGCCGGGTGCGGC
TGTGGGGCTCTATTGCCTTTGTGATTGGTTCAGCGCTGACCGGCAAGCTGGTGAGCCTGTTCGATTACCGGGCGATCCTG
CTGATGCTAAGCCTGGGGGTCGCCTCGATGCTGCTCGGCATGCTGCTTAAGCCGTCGGTGATGCCCCAGGGGGAGTCGCG
CCAGCAGCAGGGGGCCGGAATGGCGGCCTGGCTGACGCTGGTGCGCCAAAGCTGGCGCTTTCTCGCCTGCGTTTGTCTGC
TGCAGGGAGCGCATGCCGCCTACTATGGCTTTAGCGCCATCTACTGGCAGCAGGCCGGCTATTCCGCCTCGGCGGTCGGT
TATCTGTGGTCGTTAGGCGTGGTGGCGGAAGTGGTGATCTTCGCGTTGAGTAAAAAGGTGTTCCGCCGCTTCAGCGCCCG
CGACCTGCTGTTGCTCTCCGCCGCCTGCGGGCTGATTCGCTGGGGACTGATGGGCTGGACCACGGCGCTGCCGGGACTCA
TCCTTGCGCAGATCCTTCACTGTGGCACCTTCACGGTGTGTCATCTGGCGGCGATGCGCTATATCGCCGCCCGTCAGGGT
AGCGAAGTGATCCGTCTGCAGGCCGTCTACTCCGCGGTGGCGATGGGCGGCAGTATTGCCATCATGACCGTCTTCGCCGG
TTTCCTCTATCAGCACCTGCACCAGGGCGTATTCTGGGTGATGGCCCTGCTGACGCTCCCGGCGATGGCTATACGGCCAA
AAGCGGTGGCGGCCTAG

Upstream 100 bases:

>100_bases
ATCATCGAGGGGGCATAAATAACGAGCTATCAGCAGACAAGAGCATCTTGCGCCCGCCGGGGTTTATCGCCAGACTATCG
CCACCATTCGGGAGGAAATC

Downstream 100 bases:

>100_bases
TCCTCGAGCATGGCGCAGATATGCTGCTGTTGGCGTTCAGTGAAGTAGTTCTCCGCGTGGATCAGCGGCGGCGAAAACAG
CGGCAGCGCCGTCGCATAGG

Product: putative 3-phenylpropionic acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MVLHSTRWLALSYFTYFFSYGIFLPFWSVWLAGNGLTPETIGILLGAGLVARFLGSLLIAPRVSDPSRLIAALRVLALLT
LLFALAFWAGSHVAWLLAIIIGFNLFFSPLVPLTDALANTWQKQITMDYGRVRLWGSIAFVIGSALTGKLVSLFDYRAIL
LMLSLGVASMLLGMLLKPSVMPQGESRQQQGAGMAAWLTLVRQSWRFLACVCLLQGAHAAYYGFSAIYWQQAGYSASAVG
YLWSLGVVAEVVIFALSKKVFRRFSARDLLLLSAACGLIRWGLMGWTTALPGLILAQILHCGTFTVCHLAAMRYIAARQG
SEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLHQGVFWVMALLTLPAMAIRPKAVAA

Sequences:

>Translated_378_residues
MVLHSTRWLALSYFTYFFSYGIFLPFWSVWLAGNGLTPETIGILLGAGLVARFLGSLLIAPRVSDPSRLIAALRVLALLT
LLFALAFWAGSHVAWLLAIIIGFNLFFSPLVPLTDALANTWQKQITMDYGRVRLWGSIAFVIGSALTGKLVSLFDYRAIL
LMLSLGVASMLLGMLLKPSVMPQGESRQQQGAGMAAWLTLVRQSWRFLACVCLLQGAHAAYYGFSAIYWQQAGYSASAVG
YLWSLGVVAEVVIFALSKKVFRRFSARDLLLLSAACGLIRWGLMGWTTALPGLILAQILHCGTFTVCHLAAMRYIAARQG
SEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLHQGVFWVMALLTLPAMAIRPKAVAA
>Mature_378_residues
MVLHSTRWLALSYFTYFFSYGIFLPFWSVWLAGNGLTPETIGILLGAGLVARFLGSLLIAPRVSDPSRLIAALRVLALLT
LLFALAFWAGSHVAWLLAIIIGFNLFFSPLVPLTDALANTWQKQITMDYGRVRLWGSIAFVIGSALTGKLVSLFDYRAIL
LMLSLGVASMLLGMLLKPSVMPQGESRQQQGAGMAAWLTLVRQSWRFLACVCLLQGAHAAYYGFSAIYWQQAGYSASAVG
YLWSLGVVAEVVIFALSKKVFRRFSARDLLLLSAACGLIRWGLMGWTTALPGLILAQILHCGTFTVCHLAAMRYIAARQG
SEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLHQGVFWVMALLTLPAMAIRPKAVAA

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=378, Percent_Identity=83.5978835978836, Blast_Score=619, Evalue=1e-179,
Organism=Escherichia coli, GI1788415, Length=336, Percent_Identity=24.702380952381, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 41269; Mature: 41269

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLHSTRWLALSYFTYFFSYGIFLPFWSVWLAGNGLTPETIGILLGAGLVARFLGSLLIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
PRVSDPSRLIAALRVLALLTLLFALAFWAGSHVAWLLAIIIGFNLFFSPLVPLTDALANT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQKQITMDYGRVRLWGSIAFVIGSALTGKLVSLFDYRAILLMLSLGVASMLLGMLLKPSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPQGESRQQQGAGMAAWLTLVRQSWRFLACVCLLQGAHAAYYGFSAIYWQQAGYSASAVG
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
YLWSLGVVAEVVIFALSKKVFRRFSARDLLLLSAACGLIRWGLMGWTTALPGLILAQILH
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLHQGVFWV
HCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MALLTLPAMAIRPKAVAA
HHHHHHHHHHCCCHHHCC
>Mature Secondary Structure
MVLHSTRWLALSYFTYFFSYGIFLPFWSVWLAGNGLTPETIGILLGAGLVARFLGSLLIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
PRVSDPSRLIAALRVLALLTLLFALAFWAGSHVAWLLAIIIGFNLFFSPLVPLTDALANT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQKQITMDYGRVRLWGSIAFVIGSALTGKLVSLFDYRAILLMLSLGVASMLLGMLLKPSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPQGESRQQQGAGMAAWLTLVRQSWRFLACVCLLQGAHAAYYGFSAIYWQQAGYSASAVG
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
YLWSLGVVAEVVIFALSKKVFRRFSARDLLLLSAACGLIRWGLMGWTTALPGLILAQILH
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLHQGVFWV
HCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MALLTLPAMAIRPKAVAA
HHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]