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The map label for this gene is bglK

Identifier: 238895950

GI number: 238895950

Start: 3898335

End: 3899228

Strand: Reverse

Name: bglK

Synonym: KP1_4075

Alternate gene names: 238895950

Gene position: 3899228-3898335 (Counterclockwise)

Preceding gene: 238895955

Following gene: 238895949

Centisome position: 74.29

GC content: 58.17

Gene sequence:

>894_bases
ATGAAGATTGCGGCATTTGATATCGGTGGCACCGCGTTAAAGATGGGCGTGATGGCCCGCGACGGCAGGCTGCTGGAAAC
CGCCAGGCAGTCAATCAATGACAGCGATGGCGATCGGATCTTACAGGCAATGCTGTCGTGGCTGGCGGCCCATCCGTCGT
GTGAAGGAATAGCCATCAGCGCGCCGGGCTATATCGATCCGCACAGCGGTCTTATCACCATGGGCGGCGCTATCCGTCGA
TTTGATAACTTCGCCATGAAATCGTGGCTCGAGACGCGAACCGGGCTGCCGGTCTCGGTGGAAAACGACGCCAACTGTGT
GCTGCTGGCCGAGCGCTGGCAGGGCAAAGCGGCGGAGATGGCCAATTTTCTGGTGCTCACTATCGGTACTGGCATCGGTG
GGGCGATTTTCTGCCAACACCAGCTGATCAACGGGGCGCGTTTTCGTGCCGGCGAATTCGGCTACATGCTTACCGACCGT
CCCGGCGGACGCGATCCTCGTCGCTATTCGATGAATGAGAACTGCACTCTGCGGGTGCTGCGCCATCGCTATGCGCAACA
TATTGGCGCGCCGCTGGATAGCGTGACAGGCGAACTGATTTTCGACCGCTATGACGCCGGCGACCCGGTTTGTCAGCGTC
TGGTCGCCGAGTTCTTCAATGGCCTGGGCCATGGCCTTTATAACCTCGTCCATATCTTCGATCCGCAGACCATTTTTATC
GGTGGCGGCGTTGTGGAACGCCCAGGATTTCTGACGCTACTGCGCCAGCATCTGGCCTGGTTCGGCATTGCCGACTATCT
CGATACCGTCAGTCACGGTAACGATGCCGGCCTGATTGGCGCGGTTTACCATTTTAATCAGCTGTATCGTTCGCCAGACG
ACGATCGACATTAG

Upstream 100 bases:

>100_bases
CCTCTACGTAAAGGAATCCTCATTATACGACTGAAACCGGTTTCCTTGTTGGTTTGCCACGCATTTTGTCGGTGATTGAC
GCGGGTCAGGAGAGGGATGA

Downstream 100 bases:

>100_bases
GGAGAGACTATGTCCGGATTTAAAGCAGGTTTTCTGTGGGGCGGCGCGGTCGCAGCGCATCAGTTAGAGGGCGGCTGGCA
GGAGGGCGGCAAGGGGATCA

Product: putative beta-glucoside kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKIAAFDIGGTALKMGVMARDGRLLETARQSINDSDGDRILQAMLSWLAAHPSCEGIAISAPGYIDPHSGLITMGGAIRR
FDNFAMKSWLETRTGLPVSVENDANCVLLAERWQGKAAEMANFLVLTIGTGIGGAIFCQHQLINGARFRAGEFGYMLTDR
PGGRDPRRYSMNENCTLRVLRHRYAQHIGAPLDSVTGELIFDRYDAGDPVCQRLVAEFFNGLGHGLYNLVHIFDPQTIFI
GGGVVERPGFLTLLRQHLAWFGIADYLDTVSHGNDAGLIGAVYHFNQLYRSPDDDRH

Sequences:

>Translated_297_residues
MKIAAFDIGGTALKMGVMARDGRLLETARQSINDSDGDRILQAMLSWLAAHPSCEGIAISAPGYIDPHSGLITMGGAIRR
FDNFAMKSWLETRTGLPVSVENDANCVLLAERWQGKAAEMANFLVLTIGTGIGGAIFCQHQLINGARFRAGEFGYMLTDR
PGGRDPRRYSMNENCTLRVLRHRYAQHIGAPLDSVTGELIFDRYDAGDPVCQRLVAEFFNGLGHGLYNLVHIFDPQTIFI
GGGVVERPGFLTLLRQHLAWFGIADYLDTVSHGNDAGLIGAVYHFNQLYRSPDDDRH
>Mature_297_residues
MKIAAFDIGGTALKMGVMARDGRLLETARQSINDSDGDRILQAMLSWLAAHPSCEGIAISAPGYIDPHSGLITMGGAIRR
FDNFAMKSWLETRTGLPVSVENDANCVLLAERWQGKAAEMANFLVLTIGTGIGGAIFCQHQLINGARFRAGEFGYMLTDR
PGGRDPRRYSMNENCTLRVLRHRYAQHIGAPLDSVTGELIFDRYDAGDPVCQRLVAEFFNGLGHGLYNLVHIFDPQTIFI
GGGVVERPGFLTLLRQHLAWFGIADYLDTVSHGNDAGLIGAVYHFNQLYRSPDDDRH

Specific function: Catalyzes the ATP-dependent phosphorylation of a wide variety of beta-D-glucosides, to produce 6-phospho-beta-D- glucosides including cellobiose-6'-P, gentiobiose-6'-P, cellobiitol-6-P, salicin-6-P, and arbutin-6-P. Is not able to phosphorylate alpha-D-gl

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family

Homologues:

Organism=Homo sapiens, GI298566325, Length=262, Percent_Identity=26.3358778625954, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI298566315, Length=262, Percent_Identity=26.3358778625954, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4885285, Length=262, Percent_Identity=26.3358778625954, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI190014632, Length=262, Percent_Identity=26.3358778625954, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787363, Length=303, Percent_Identity=26.7326732673267, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082127, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081733, Length=303, Percent_Identity=22.1122112211221, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786891, Length=233, Percent_Identity=23.175965665236, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): BGLK_KLEPN (Q93LQ8)

Other databases:

- EMBL:   AY035305
- ProteinModelPortal:   Q93LQ8
- InterPro:   IPR000600

Pfam domain/function: PF00480 ROK

EC number: =2.7.1.85

Molecular weight: Translated: 32698; Mature: 32698

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS01125 ROK; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAAFDIGGTALKMGVMARDGRLLETARQSINDSDGDRILQAMLSWLAAHPSCEGIAIS
CEEEEEECCCHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
APGYIDPHSGLITMGGAIRRFDNFAMKSWLETRTGLPVSVENDANCVLLAERWQGKAAEM
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHH
ANFLVLTIGTGIGGAIFCQHQLINGARFRAGEFGYMLTDRPGGRDPRRYSMNENCTLRVL
HCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHH
RHRYAQHIGAPLDSVTGELIFDRYDAGDPVCQRLVAEFFNGLGHGLYNLVHIFDPQTIFI
HHHHHHHHCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
GGGVVERPGFLTLLRQHLAWFGIADYLDTVSHGNDAGLIGAVYHFNQLYRSPDDDRH
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKIAAFDIGGTALKMGVMARDGRLLETARQSINDSDGDRILQAMLSWLAAHPSCEGIAIS
CEEEEEECCCHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
APGYIDPHSGLITMGGAIRRFDNFAMKSWLETRTGLPVSVENDANCVLLAERWQGKAAEM
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHH
ANFLVLTIGTGIGGAIFCQHQLINGARFRAGEFGYMLTDRPGGRDPRRYSMNENCTLRVL
HCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHH
RHRYAQHIGAPLDSVTGELIFDRYDAGDPVCQRLVAEFFNGLGHGLYNLVHIFDPQTIFI
HHHHHHHHCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
GGGVVERPGFLTLLRQHLAWFGIADYLDTVSHGNDAGLIGAVYHFNQLYRSPDDDRH
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12110692