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The map label for this gene is yfgF [H]

Identifier: 238895955

GI number: 238895955

Start: 3904998

End: 3907226

Strand: Reverse

Name: yfgF [H]

Synonym: KP1_4080

Alternate gene names: 238895955

Gene position: 3907226-3904998 (Counterclockwise)

Preceding gene: 238895957

Following gene: 238895950

Centisome position: 74.44

GC content: 52.89

Gene sequence:

>2229_bases
ATGAATTTATTAAAATACTATCAACAATATCGCGACAAGTGGTGGGCTTTACCGCTCGTTCTGCCTGCGCTGTTATTACC
GGTCGCCAGATGGGCGAATACCTACACCATGCTCAATGGTCATATGGTATTTTTGTATTATCTTCCCCTGGCGCTGGTGC
TCAGCCTGATGATGTTTTTTGGTTGGGCGGCGATCCCTGGCATTATTATTGGCCTGCTGTTAACTCTGGCCCACGGCATG
ATGTTTGAGCAGTCCATCGGTGTACTGTTCCATTTCCTTATCCCCTGCGTGCTCTGCTGGGGCGGCTACCGCATTTTTGT
CCCCCAGCGTCAGCAGGTCTCACACGGCAACGTCCGACTGATGCCGCATCGTCTGTTCTGGCAAATGCTGCTCCCTTCGG
TCATTTTTCTGATTTTGTCACAGATTGCCGAATATCTTGGACTTCATCCGCGCACAACGGAAATGACCGGCGTTACGCCA
TTTAGTTTACGTTCATTAATCACCTTTCAGGCGCTAATGGTAGGGTGCCTGACCGGCATGCCGCTGTGTTATTTTGTGTT
ACGGGTCATTCGTAATCCTTTTCATTTACGCGGCTTTATTTCTCAGGTTCGCTTACAAATTGATCCAAAAATAAAAAAAA
TTGAAATTATTTGCTGGGCGACGGTATTAATTCTGCTACTGTGGCTATTATTGATGCCGCTTAATGATAGCAGCACCATA
TTTAGTACGAATTATACGTTGTCATTGCTGATGCCGGTGATGCTCTGGGGTGCCATGCGTTTTGGCTATCGCTTTATCTC
ACTGATCTGGACGCCGGTGCTGATTGCCGTGATCCATTTTCATTACCGTTACTTACCAATTTACCCAAGCTATAACACCC
AGTTGGCGATCACCTCATCAAGCTATCTGGTATTCTCGTTTATTGTCGCCTATACGGCGATGTTGGCGACACAGCAGCGG
CTGATCTACGCTCGCGTCCGGCAGATGGCCTTCCTCGACCCGGTGGTTCATATGCCGAACTTGCGGGCGCTGAGCCGGGC
GCTCAACGGCACGAGCTGGTCGACGCTCTGTTTTCTGCGCATTCCTGAGCTTGAACTGCTGGGGCGCCACTATGGGGTAC
TTTTGCGAATCCAGTATAAGCAAATGCTGGCGAACCACCTGAGAACGCTGCTGCAGCCCAACGAAGCGGTATATCATCTT
GCCGGTCACGATTTAGTGTTCCGTCTCAATAGCGAAGGGCACCAGGCGCGCATTCACTTAATTGACCGCTCCCTGCGACA
GTTCCGTTTCCACTGGGACGGGGTCCCCCTGCAGCCGCGGATCGGCATGAGCTATTGCAACGTTCGCTCGCCGGTCAAGC
ATCTGTATTTACTGCTTGGCGAGTTGAACACCATTGCCGACATGTCGTTAGCCAGCGGCCATCCGGAAAATTTACAGCGC
CGCGGCGCGGGCCATGTTCAGCAGGATCTGAAAGATAAAGTCGTGATGATGAACCGCATTCTCAAAGCGCTGGAACATGA
CCATTTTGTCCTGATGGCGCAGCCTATCCAGGGCATTCGCGGCGATCGCTATCATGAAGTGCTGGTGAGGATGGAAGGGG
AGTCGGGTGAGCTAACGGGGCCAAACGAGTTCTTGCCGGTGGCGCACGAGTTTGGGCTGTCCACGCGGGTGGACCAGTGG
GTTATTGAGCATACGCTGGCCTTTATGGACGCCAACCGGCGGGCGCTGCCCGGTCTGCGGCTGGCGATCAATCTTTCTCC
GGTGTCGCTGAGCCGCAGCCAGTTTCCTCAGGAGGTCGAAGCGCTGCTGCAGGCCTACAACATTGAGCCATGGCAGATTA
TTTTCGAGCTGACCGAGAACTACGCGCTCAGCAATCCCGAGCTGGTCTGCCAGACTTTAGAGCATCTGCGGGCGCTGGGC
TGCCGGGTGGCGATCGATGATTTTGGTACCGGCTACGCCAGCTACGCCCGGTTAAAAACAATGAACGTCGACATTCTTAA
AATCGACGGCAGTTTTATTCGCAATCTGCTTGCCAGCAGTCTTGATTACCAGGTCGTGGACTCTATTTGTCGTCTGGCGC
GTATGAAGAACATGCAGGTGGTGGCCGAATATGTGGAGTCGCCGGAAATACGTCAGGCGGTCATCACGCTGGGGATCGAT
TATATGCAGGGCTATGATATCGGGGTACCGGTACCTCTGACGCAGTTGGCGGAGGAGATGACCGGCTGA

Upstream 100 bases:

>100_bases
CGGACGTTACCGTATCGTTATTATTTACGCGGTCAGCATGGGTGGTTGGATGCCTGCCTGAATATGCCTCGCGGGAGCAG
AGGCACTCTGTAGAGCACCT

Downstream 100 bases:

>100_bases
ACAGCAAAAATCCGGGCGTAAGCGCCCGGCTCGGTTGATTGCCAGAGATACGATCAGGCGTCTGGCTCTTCTTCAGCAAT
CTTCAGCATCCATTCCGGCA

Product: putative cytochrome C-type biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 742; Mature: 742

Protein sequence:

>742_residues
MNLLKYYQQYRDKWWALPLVLPALLLPVARWANTYTMLNGHMVFLYYLPLALVLSLMMFFGWAAIPGIIIGLLLTLAHGM
MFEQSIGVLFHFLIPCVLCWGGYRIFVPQRQQVSHGNVRLMPHRLFWQMLLPSVIFLILSQIAEYLGLHPRTTEMTGVTP
FSLRSLITFQALMVGCLTGMPLCYFVLRVIRNPFHLRGFISQVRLQIDPKIKKIEIICWATVLILLLWLLLMPLNDSSTI
FSTNYTLSLLMPVMLWGAMRFGYRFISLIWTPVLIAVIHFHYRYLPIYPSYNTQLAITSSSYLVFSFIVAYTAMLATQQR
LIYARVRQMAFLDPVVHMPNLRALSRALNGTSWSTLCFLRIPELELLGRHYGVLLRIQYKQMLANHLRTLLQPNEAVYHL
AGHDLVFRLNSEGHQARIHLIDRSLRQFRFHWDGVPLQPRIGMSYCNVRSPVKHLYLLLGELNTIADMSLASGHPENLQR
RGAGHVQQDLKDKVVMMNRILKALEHDHFVLMAQPIQGIRGDRYHEVLVRMEGESGELTGPNEFLPVAHEFGLSTRVDQW
VIEHTLAFMDANRRALPGLRLAINLSPVSLSRSQFPQEVEALLQAYNIEPWQIIFELTENYALSNPELVCQTLEHLRALG
CRVAIDDFGTGYASYARLKTMNVDILKIDGSFIRNLLASSLDYQVVDSICRLARMKNMQVVAEYVESPEIRQAVITLGID
YMQGYDIGVPVPLTQLAEEMTG

Sequences:

>Translated_742_residues
MNLLKYYQQYRDKWWALPLVLPALLLPVARWANTYTMLNGHMVFLYYLPLALVLSLMMFFGWAAIPGIIIGLLLTLAHGM
MFEQSIGVLFHFLIPCVLCWGGYRIFVPQRQQVSHGNVRLMPHRLFWQMLLPSVIFLILSQIAEYLGLHPRTTEMTGVTP
FSLRSLITFQALMVGCLTGMPLCYFVLRVIRNPFHLRGFISQVRLQIDPKIKKIEIICWATVLILLLWLLLMPLNDSSTI
FSTNYTLSLLMPVMLWGAMRFGYRFISLIWTPVLIAVIHFHYRYLPIYPSYNTQLAITSSSYLVFSFIVAYTAMLATQQR
LIYARVRQMAFLDPVVHMPNLRALSRALNGTSWSTLCFLRIPELELLGRHYGVLLRIQYKQMLANHLRTLLQPNEAVYHL
AGHDLVFRLNSEGHQARIHLIDRSLRQFRFHWDGVPLQPRIGMSYCNVRSPVKHLYLLLGELNTIADMSLASGHPENLQR
RGAGHVQQDLKDKVVMMNRILKALEHDHFVLMAQPIQGIRGDRYHEVLVRMEGESGELTGPNEFLPVAHEFGLSTRVDQW
VIEHTLAFMDANRRALPGLRLAINLSPVSLSRSQFPQEVEALLQAYNIEPWQIIFELTENYALSNPELVCQTLEHLRALG
CRVAIDDFGTGYASYARLKTMNVDILKIDGSFIRNLLASSLDYQVVDSICRLARMKNMQVVAEYVESPEIRQAVITLGID
YMQGYDIGVPVPLTQLAEEMTG
>Mature_742_residues
MNLLKYYQQYRDKWWALPLVLPALLLPVARWANTYTMLNGHMVFLYYLPLALVLSLMMFFGWAAIPGIIIGLLLTLAHGM
MFEQSIGVLFHFLIPCVLCWGGYRIFVPQRQQVSHGNVRLMPHRLFWQMLLPSVIFLILSQIAEYLGLHPRTTEMTGVTP
FSLRSLITFQALMVGCLTGMPLCYFVLRVIRNPFHLRGFISQVRLQIDPKIKKIEIICWATVLILLLWLLLMPLNDSSTI
FSTNYTLSLLMPVMLWGAMRFGYRFISLIWTPVLIAVIHFHYRYLPIYPSYNTQLAITSSSYLVFSFIVAYTAMLATQQR
LIYARVRQMAFLDPVVHMPNLRALSRALNGTSWSTLCFLRIPELELLGRHYGVLLRIQYKQMLANHLRTLLQPNEAVYHL
AGHDLVFRLNSEGHQARIHLIDRSLRQFRFHWDGVPLQPRIGMSYCNVRSPVKHLYLLLGELNTIADMSLASGHPENLQR
RGAGHVQQDLKDKVVMMNRILKALEHDHFVLMAQPIQGIRGDRYHEVLVRMEGESGELTGPNEFLPVAHEFGLSTRVDQW
VIEHTLAFMDANRRALPGLRLAINLSPVSLSRSQFPQEVEALLQAYNIEPWQIIFELTENYALSNPELVCQTLEHLRALG
CRVAIDDFGTGYASYARLKTMNVDILKIDGSFIRNLLASSLDYQVVDSICRLARMKNMQVVAEYVESPEIRQAVITLGID
YMQGYDIGVPVPLTQLAEEMTG

Specific function: Truncated proteins consisting of the GGDEF/EAL domains (residues 319-747) or of the EAL domain alone (481-747) have c-di- GMP phosphodiesterase activity. They do not have diguanylate cyclase activity. Cyclic-di-GMP is a second messenger which controls cel

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788849, Length=740, Percent_Identity=58.7837837837838, Blast_Score=925, Evalue=0.0,
Organism=Escherichia coli, GI87082096, Length=734, Percent_Identity=28.7465940054496, Blast_Score=298, Evalue=1e-81,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=30.9322033898305, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1787541, Length=435, Percent_Identity=25.0574712643678, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI226510982, Length=433, Percent_Identity=26.3279445727483, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788502, Length=241, Percent_Identity=30.2904564315353, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081921, Length=470, Percent_Identity=24.468085106383, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI87081743, Length=231, Percent_Identity=29.8701298701299, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786507, Length=215, Percent_Identity=30.2325581395349, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081845, Length=240, Percent_Identity=29.5833333333333, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87081980, Length=246, Percent_Identity=28.4552845528455, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787055, Length=252, Percent_Identity=26.984126984127, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789650, Length=224, Percent_Identity=26.3392857142857, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787410, Length=164, Percent_Identity=31.7073170731707, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895 [H]

Pfam domain/function: PF00563 EAL; PF05231 MASE1 [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 85131; Mature: 85131

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLKYYQQYRDKWWALPLVLPALLLPVARWANTYTMLNGHMVFLYYLPLALVLSLMMFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCHHHHHHHHHHHHHHHHHH
GWAAIPGIIIGLLLTLAHGMMFEQSIGVLFHFLIPCVLCWGGYRIFVPQRQQVSHGNVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHCCCCCCEEE
MPHRLFWQMLLPSVIFLILSQIAEYLGLHPRTTEMTGVTPFSLRSLITFQALMVGCLTGM
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PLCYFVLRVIRNPFHLRGFISQVRLQIDPKIKKIEIICWATVLILLLWLLLMPLNDSSTI
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCCE
FSTNYTLSLLMPVMLWGAMRFGYRFISLIWTPVLIAVIHFHYRYLPIYPSYNTQLAITSS
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECC
SYLVFSFIVAYTAMLATQQRLIYARVRQMAFLDPVVHMPNLRALSRALNGTSWSTLCFLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEE
IPELELLGRHYGVLLRIQYKQMLANHLRTLLQPNEAVYHLAGHDLVFRLNSEGHQARIHL
CCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCHHEEEECCCEEEEEECCCCCEEHHHH
IDRSLRQFRFHWDGVPLQPRIGMSYCNVRSPVKHLYLLLGELNTIADMSLASGHPENLQR
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RGAGHVQQDLKDKVVMMNRILKALEHDHFVLMAQPIQGIRGDRYHEVLVRMEGESGELTG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHEEEHEEEECCCCCCCC
PNEFLPVAHEFGLSTRVDQWVIEHTLAFMDANRRALPGLRLAINLSPVSLSRSQFPQEVE
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHCCHHHHH
ALLQAYNIEPWQIIFELTENYALSNPELVCQTLEHLRALGCRVAIDDFGTGYASYARLKT
HHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHEEE
MNVDILKIDGSFIRNLLASSLDYQVVDSICRLARMKNMQVVAEYVESPEIRQAVITLGID
CCEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
YMQGYDIGVPVPLTQLAEEMTG
HHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNLLKYYQQYRDKWWALPLVLPALLLPVARWANTYTMLNGHMVFLYYLPLALVLSLMMFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCHHHHHHHHHHHHHHHHHH
GWAAIPGIIIGLLLTLAHGMMFEQSIGVLFHFLIPCVLCWGGYRIFVPQRQQVSHGNVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHCCCCCCEEE
MPHRLFWQMLLPSVIFLILSQIAEYLGLHPRTTEMTGVTPFSLRSLITFQALMVGCLTGM
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PLCYFVLRVIRNPFHLRGFISQVRLQIDPKIKKIEIICWATVLILLLWLLLMPLNDSSTI
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCCE
FSTNYTLSLLMPVMLWGAMRFGYRFISLIWTPVLIAVIHFHYRYLPIYPSYNTQLAITSS
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECC
SYLVFSFIVAYTAMLATQQRLIYARVRQMAFLDPVVHMPNLRALSRALNGTSWSTLCFLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEE
IPELELLGRHYGVLLRIQYKQMLANHLRTLLQPNEAVYHLAGHDLVFRLNSEGHQARIHL
CCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCHHEEEECCCEEEEEECCCCCEEHHHH
IDRSLRQFRFHWDGVPLQPRIGMSYCNVRSPVKHLYLLLGELNTIADMSLASGHPENLQR
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RGAGHVQQDLKDKVVMMNRILKALEHDHFVLMAQPIQGIRGDRYHEVLVRMEGESGELTG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHEEEHEEEECCCCCCCC
PNEFLPVAHEFGLSTRVDQWVIEHTLAFMDANRRALPGLRLAINLSPVSLSRSQFPQEVE
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHCCHHHHH
ALLQAYNIEPWQIIFELTENYALSNPELVCQTLEHLRALGCRVAIDDFGTGYASYARLKT
HHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHEEE
MNVDILKIDGSFIRNLLASSLDYQVVDSICRLARMKNMQVVAEYVESPEIRQAVITLGID
CCEEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
YMQGYDIGVPVPLTQLAEEMTG
HHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]