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The map label for this gene is yfcG [H]

Identifier: 238895821

GI number: 238895821

Start: 3767584

End: 3768213

Strand: Direct

Name: yfcG [H]

Synonym: KP1_3938

Alternate gene names: 238895821

Gene position: 3767584-3768213 (Clockwise)

Preceding gene: 238895817

Following gene: 238895822

Centisome position: 71.78

GC content: 56.98

Gene sequence:

>630_bases
ATGATCGATCTTTACTATGCACCCACCCCAAACGGCCACAAAATCACCCTGTTCCTCGAAGAGGCGGAGCTAGCCTATCG
GCTAATTCGGGTCGATATCGGCAAAGGGGAACAATTTCATCCGCAGTTTCTGGCGATTTCGCCGAATAATAAAGTTCCGG
CTATCGTCGACCACATGCCTGCTGACGGCGGGGCGCCGTTGAGCGTTTTCGAGTCCGGCGCCATCCTGCTCTATCTGGCG
GAAAAAAGCGGTAAGCTGCTGAGCGGCGAGCTGCGGGAACGCTACGTCACGCTGCAGTGGCTGTTCTGGCAGGTCGGCGG
GCTGGGGCCGATGCTGGGGCAAAATCAACATTTTTCCCACACCGCGCCGCAAACCGTGCCCTACGCTATTGAACGTTTTC
AGGTGGAAACCCAACGACTGTATGGGGTGTTAAATCAGCGCCTGGGATGCAGCCCGTGGCTTGGCGGCGACCACTACAGT
ATCGCCGACATCGCCGCCTGGCCCTGGGTGAACTGCCATGTCCGACAGCGTATCGATCTGGCGAACTATCCGGCGGTGCA
CAACTGGTATGAGCGCATTAAGCAGCGGCCGGCAACGGCGGAAGCGATGTTAAAAATTCAGCTTTATTAA

Upstream 100 bases:

>100_bases
ACTCGTCGCCTGGCTGCCGGGTCGCTTGCGGAATTTCTCCCGGGTGGCGCAGCTTCACCTATACTCGAACAGTTTGCGAC
CCACGACGGCGGGAAATATT

Downstream 100 bases:

>100_bases
CCCCCTGCTCGCCCGTCGCGCTTTGTTGTATGATTGCAGGACTTACACCACGGAGGAAGCCTGCAATGTCTCAACCAGAC
GCCATTATTCGTATTAAGAA

Product: putative S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIDLYYAPTPNGHKITLFLEEAELAYRLIRVDIGKGEQFHPQFLAISPNNKVPAIVDHMPADGGAPLSVFESGAILLYLA
EKSGKLLSGELRERYVTLQWLFWQVGGLGPMLGQNQHFSHTAPQTVPYAIERFQVETQRLYGVLNQRLGCSPWLGGDHYS
IADIAAWPWVNCHVRQRIDLANYPAVHNWYERIKQRPATAEAMLKIQLY

Sequences:

>Translated_209_residues
MIDLYYAPTPNGHKITLFLEEAELAYRLIRVDIGKGEQFHPQFLAISPNNKVPAIVDHMPADGGAPLSVFESGAILLYLA
EKSGKLLSGELRERYVTLQWLFWQVGGLGPMLGQNQHFSHTAPQTVPYAIERFQVETQRLYGVLNQRLGCSPWLGGDHYS
IADIAAWPWVNCHVRQRIDLANYPAVHNWYERIKQRPATAEAMLKIQLY
>Mature_209_residues
MIDLYYAPTPNGHKITLFLEEAELAYRLIRVDIGKGEQFHPQFLAISPNNKVPAIVDHMPADGGAPLSVFESGAILLYLA
EKSGKLLSGELRERYVTLQWLFWQVGGLGPMLGQNQHFSHTAPQTVPYAIERFQVETQRLYGVLNQRLGCSPWLGGDHYS
IADIAAWPWVNCHVRQRIDLANYPAVHNWYERIKQRPATAEAMLKIQLY

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=208, Percent_Identity=79.3269230769231, Blast_Score=347, Evalue=5e-97,
Organism=Escherichia coli, GI87082195, Length=219, Percent_Identity=41.0958904109589, Blast_Score=153, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6324100, Length=233, Percent_Identity=33.9055793991416, Blast_Score=125, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28571670, Length=164, Percent_Identity=30.4878048780488, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17864592, Length=201, Percent_Identity=28.3582089552239, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17864598, Length=208, Percent_Identity=29.8076923076923, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45549270, Length=201, Percent_Identity=27.363184079602, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85725204, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737923, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864594, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23742; Mature: 23742

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYAPTPNGHKITLFLEEAELAYRLIRVDIGKGEQFHPQFLAISPNNKVPAIVDHMP
CEEEEECCCCCCCEEEEEEECHHHEEEEEEEECCCCCCCCCEEEEECCCCCCCCCEECCC
ADGGAPLSVFESGAILLYLAEKSGKLLSGELRERYVTLQWLFWQVGGLGPMLGQNQHFSH
CCCCCCHHEECCCEEEEEEECCCCCEEECHHHHHEEHEEEEEEHHCCCCCCCCCCCCCCC
TAPQTVPYAIERFQVETQRLYGVLNQRLGCSPWLGGDHYSIADIAAWPWVNCHVRQRIDL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCCCCEEHHEECCC
ANYPAVHNWYERIKQRPATAEAMLKIQLY
CCCCHHHHHHHHHHCCCCCCCEEEEEEEC
>Mature Secondary Structure
MIDLYYAPTPNGHKITLFLEEAELAYRLIRVDIGKGEQFHPQFLAISPNNKVPAIVDHMP
CEEEEECCCCCCCEEEEEEECHHHEEEEEEEECCCCCCCCCEEEEECCCCCCCCCEECCC
ADGGAPLSVFESGAILLYLAEKSGKLLSGELRERYVTLQWLFWQVGGLGPMLGQNQHFSH
CCCCCCHHEECCCEEEEEEECCCCCEEECHHHHHEEHEEEEEEHHCCCCCCCCCCCCCCC
TAPQTVPYAIERFQVETQRLYGVLNQRLGCSPWLGGDHYSIADIAAWPWVNCHVRQRIDL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCCCCEEHHEECCC
ANYPAVHNWYERIKQRPATAEAMLKIQLY
CCCCHHHHHHHHHHCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]