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The map label for this gene is pta [H]

Identifier: 238895817

GI number: 238895817

Start: 3763302

End: 3765449

Strand: Direct

Name: pta [H]

Synonym: KP1_3934

Alternate gene names: 238895817

Gene position: 3763302-3765449 (Clockwise)

Preceding gene: 238895816

Following gene: 238895821

Centisome position: 71.7

GC content: 60.01

Gene sequence:

>2148_bases
GTGTCCCGTACTATCATGTTAATTCCTACCGGTACCAGCGTAGGTCTGACCAGCGTCAGCCTCGGTGTGATCCGCGCTAT
GGAACGCAAAGGCGTTCGTCTGAGCGTCTTTAAACCTATCGCCCAGCCGCGTTCCGGTGGCGATGCCCCAGACCAGACCA
CCACCATCGTTCGCGCCAGCTCCTCCACCACCACCGCCGCTGAACCGCTGAAGATGAGCCATGTTGAGTCTCTGCTCTCC
AGCAATCAGAAAGATGTGCTGATGGAAGAGATCATTGCCAACTACCACGCGAATACTCAGGACGCGGAAGTGGTGCTGGT
GGAAGGCCTGGTACCGACCCGTAAGCATCAGTTCGCCCAGGCGCTGAACTTTGAAATCGCCAAAACGCTGAACGCTGAAA
TCGTCTTCGTGATGTCTCAGGGCACCGACACGCCAGAACAGCTGAACGAGCGTATCGAACTGACCCGTAACAGCTTTGGC
GGCGCCAAAAATACCAGCATCACCGGCGTTATCGTCAACAAACTGAATGCCCCTGTCGACGATCAGGGCCGTACCCGTCC
TGACCTGTCGGAAATTTTCGACGACTCGTCGAAAGCAAAAATCGTGAAGATTGACCCGGCTCAGCTGCAGAAAGGCAGCA
CGCTGCCGGTGCTGGGCGCAGTGCCATGGAGCTTCGATCTGATCGCGACCCGCGCGATCGACATGGCGCACCATCTGAAT
GCGACCATCATCAACGAAGGCGATATCAATACCCGCCGCGTGAAATCCGTGACTTTCTGCGCGCGCAGCATCCCGCACAT
GCTGGAACACTTCCGCCCTGGTTCTCTGCTGGTTACCTCCGCAGACCGTCCTGACGTGCTGGTTGCGGCCTGCCTGGCGG
CAATGAACGGCGTGGAAATCGGCGCCATTCTGCTGACCGGCGGCTATGAAATGGACGCGCGCATCAGCAAGCTGTGTGAA
CGCGCTTTCGCGACCGGCCTGCCGGTATTCATGGTCAACACCAACACCTGGCAGACCTCCCTGAGCCTGCAGAGCTTTAA
CCTCGAAGTACCGGTTGACGATCACGAGCGTATCGAGAAAGTTCAGGAATACGTGGCCAACTACATCAACGCCGACTGGA
TCGAATCGCTGACCGCGACCTCCGAGCGCAGCCGCCGTCTCTCTCCGCCAGCCTTCCGCTACCAGCTGACCGAGCTGGCG
CGCAAAGCCGGCAAACGTGTCGTTCTGCCGGAAGGCGACGAACCGCGTACCGTGAAAGCGGCGGCGATTTGCGCCGAACG
CGGGATCGCCACCTGCGTCCTGCTGGGTAACCCGGATGAGATCAACCGCGTAGCCGCGGCCCAGGGCGTTGAGCTTGGCG
CCGGCATTGAAATCGTCGATCCGGAAGTGGTTCGCGAAAGCTATGTGGGTCGCCTGGTCGAACTGCGTAAGAACAAAGGC
ATGACCGAAGCGGTCGCGCGTGAGCAGCTGGAAGACAACGTGGTTCTCGGCACCCTGATGCTGGAACAGGACGAAGTCGA
CGGTCTGGTATCCGGCGCGGTTCACACCACTGCCAACACCATTCGTCCGCCGCTGCAGCTGATCAAAACCGCGCCGGGCA
GCTCGCTGGTCTCCTCCGTGTTCTTCATGCTGCTGCCGGAACAGGTTTACGTTTACGGCGACTGCGCGATCAACCCGGAC
CCGACCGCCGAGCAGCTGGCGGAAATCGCTATTCAGTCCGCTGAATCCGCGATTGCCTTCGGCATCGAACCGCGCGTGGC
GATGCTCTCCTACTCCACCGGTACCTCCGGCGCGGGTAGCGATGTCGAGAAAGTCCGCGAAGCGACCCGTCTGGCGCAGG
AAAAACGTCCTGACCTGATGATCGACGGCCCGCTGCAGTATGACGCCGCGGTGATGGCTGACGTAGCGAAGTCCAAAGCG
CCGAACTCACCGGTAGCTGGCCGCGCGACCGTGTTCATCTTCCCGGATCTGAACACCGGTAACACCACGTACAAAGCGGT
ACAGCGCTCTGCCGACCTGATCTCCATCGGGCCGATGCTGCAGGGTATGCGCAAGCCGGTCAACGACCTGTCCCGTGGCG
CGCTGGTAGACGATATCGTCTATACCATCGCACTGACCGCGATCCAATCGGCTCAGCAGCAGAAGTAA

Upstream 100 bases:

>100_bases
CAAGTAGAGCCAACGCACGTGCAACTTGAAATATGACGGATAGCTGGCGGTGCTGTTTTGTATCCCGCCTGATACTGGCG
GTAACGAAAGAGGATATACC

Downstream 100 bases:

>100_bases
TCTGCCGCTGTGGTCAAAGCAAAAGGCAGCCGAATGGCTGCCTTTTTGTCGTCAGGAGGCGAGCGACGATTGCTGTCGCG
CGTTTGCGATCTTTATTCGC

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MSRTIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRSGGDAPDQTTTIVRASSSTTTAAEPLKMSHVESLLS
SNQKDVLMEEIIANYHANTQDAEVVLVEGLVPTRKHQFAQALNFEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRNSFG
GAKNTSITGVIVNKLNAPVDDQGRTRPDLSEIFDDSSKAKIVKIDPAQLQKGSTLPVLGAVPWSFDLIATRAIDMAHHLN
ATIINEGDINTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVAACLAAMNGVEIGAILLTGGYEMDARISKLCE
RAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELA
RKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAAAQGVELGAGIEIVDPEVVRESYVGRLVELRKNKG
MTEAVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPD
PTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKA
PNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK

Sequences:

>Translated_715_residues
MSRTIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRSGGDAPDQTTTIVRASSSTTTAAEPLKMSHVESLLS
SNQKDVLMEEIIANYHANTQDAEVVLVEGLVPTRKHQFAQALNFEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRNSFG
GAKNTSITGVIVNKLNAPVDDQGRTRPDLSEIFDDSSKAKIVKIDPAQLQKGSTLPVLGAVPWSFDLIATRAIDMAHHLN
ATIINEGDINTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVAACLAAMNGVEIGAILLTGGYEMDARISKLCE
RAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELA
RKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAAAQGVELGAGIEIVDPEVVRESYVGRLVELRKNKG
MTEAVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPD
PTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKA
PNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK
>Mature_714_residues
SRTIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRSGGDAPDQTTTIVRASSSTTTAAEPLKMSHVESLLSS
NQKDVLMEEIIANYHANTQDAEVVLVEGLVPTRKHQFAQALNFEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRNSFGG
AKNTSITGVIVNKLNAPVDDQGRTRPDLSEIFDDSSKAKIVKIDPAQLQKGSTLPVLGAVPWSFDLIATRAIDMAHHLNA
TIINEGDINTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVAACLAAMNGVEIGAILLTGGYEMDARISKLCER
AFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELAR
KAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAAAQGVELGAGIEIVDPEVVRESYVGRLVELRKNKGM
TEAVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDP
TAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAP
NSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=714, Percent_Identity=95.9383753501401, Blast_Score=1410, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=318, Percent_Identity=38.3647798742138, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1788806, Length=349, Percent_Identity=31.8051575931232, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 77226; Mature: 77095

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRSGGDAPDQTTTIVRAS
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEC
SSTTTAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTQDAEVVLVEGLVPTRKHQFAQ
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
ALNFEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRNSFGGAKNTSITGVIVNKLNAPVD
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCC
DQGRTRPDLSEIFDDSSKAKIVKIDPAQLQKGSTLPVLGAVPWSFDLIATRAIDMAHHLN
CCCCCCCCHHHHHCCCCCCEEEEECHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCC
ATIINEGDINTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVAACLAAMNGVEI
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
GAILLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEK
EEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEEECCCCHHHHHHH
VQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRVVLPEGDEPRTVKA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHH
AAICAERGIATCVLLGNPDEINRVAAAQGVELGAGIEIVDPEVVRESYVGRLVELRKNKG
HHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCC
MTEAVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSV
HHHHHHHHHHCCCEEEEEEEECCHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHH
FFMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGS
HHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCCCH
DVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTG
HHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
NTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK
CHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRTIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRSGGDAPDQTTTIVRAS
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEC
SSTTTAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTQDAEVVLVEGLVPTRKHQFAQ
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
ALNFEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRNSFGGAKNTSITGVIVNKLNAPVD
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCC
DQGRTRPDLSEIFDDSSKAKIVKIDPAQLQKGSTLPVLGAVPWSFDLIATRAIDMAHHLN
CCCCCCCCHHHHHCCCCCCEEEEECHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHCC
ATIINEGDINTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVAACLAAMNGVEI
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
GAILLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEK
EEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEEECCCCHHHHHHH
VQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRVVLPEGDEPRTVKA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHH
AAICAERGIATCVLLGNPDEINRVAAAQGVELGAGIEIVDPEVVRESYVGRLVELRKNKG
HHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCC
MTEAVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSV
HHHHHHHHHHCCCEEEEEEEECCHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHH
FFMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSAESAIAFGIEPRVAMLSYSTGTSGAGS
HHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCCCH
DVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTG
HHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
NTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK
CHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]