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The map label for this gene is nuoA

Identifier: 238895805

GI number: 238895805

Start: 3753104

End: 3753550

Strand: Reverse

Name: nuoA

Synonym: KP1_3922

Alternate gene names: 238895805

Gene position: 3753550-3753104 (Counterclockwise)

Preceding gene: 238895807

Following gene: 238895804

Centisome position: 71.52

GC content: 55.03

Gene sequence:

>447_bases
ATGCGTATGTCAACATCCACTGAAGTCATCGCTCATCATTGGGCATTCGCTATATTTCTCATCATCGCTATCGGCCTGTG
CTGCCTCATGCTCGTCGGCGGCTGGTACCTTGGCGGTCGCGCGCGCGCGCGTAGTAAAAACACGCCGTTTGAATCGGGGA
TCGACTCCGTCGGTTCGGCCCGCTTACGTCTTTCTGCGAAGTTTTATCTGGTTGCCATGTTCTTCGTTATCTTCGACGTG
GAAGCCCTGTATCTCTACGCATGGTCGACCTCTATCCGCGAGAGCGGCTGGGTCGGCTTTGTGGAAGCCGCAATTTTCAT
TTTAGTGCTACTGGCTGGTCTGGTTTATCTCGTTCGCATCGGCGCACTGGACTGGACGCCTGCGCGTTCCCGTCGCACGC
TGGTTAACCCGGAAACAGACAGTCCCACTAACCGTCATATGCAGTAA

Upstream 100 bases:

>100_bases
TTTTTTGCACGGTTATTTTTTATTCCTCCCGTGAAACGCTGTGGCGTTCATCTGCCAGTAAGAGCAGAGGGTTTTGGCGC
TACACTTTTTTGGTTAAGCA

Downstream 100 bases:

>100_bases
AAGCGAGGCAATAAGATGGATTATACGCTCACCCGCATAGATCCTAACGGTGAGAACGACCGTTACCCCCTGCAGAAACA
GGAGATCGTTACCGATCCTC

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRMSTSTEVIAHHWAFAIFLIIAIGLCCLMLVGGWYLGGRARARSKNTPFESGIDSVGSARLRLSAKFYLVAMFFVIFDV
EALYLYAWSTSIRESGWVGFVEAAIFILVLLAGLVYLVRIGALDWTPARSRRTLVNPETDSPTNRHMQ

Sequences:

>Translated_148_residues
MRMSTSTEVIAHHWAFAIFLIIAIGLCCLMLVGGWYLGGRARARSKNTPFESGIDSVGSARLRLSAKFYLVAMFFVIFDV
EALYLYAWSTSIRESGWVGFVEAAIFILVLLAGLVYLVRIGALDWTPARSRRTLVNPETDSPTNRHMQ
>Mature_148_residues
MRMSTSTEVIAHHWAFAIFLIIAIGLCCLMLVGGWYLGGRARARSKNTPFESGIDSVGSARLRLSAKFYLVAMFFVIFDV
EALYLYAWSTSIRESGWVGFVEAAIFILVLLAGLVYLVRIGALDWTPARSRRTLVNPETDSPTNRHMQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=146, Percent_Identity=91.0958904109589, Blast_Score=271, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_KLEP7 (A6TBX4)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001336325.1
- STRING:   A6TBX4
- GeneID:   5338952
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_02678
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 16565; Mature: 16565

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e88acd8)-; HASH(0x1e611e2c)-; HASH(0x1eee646c)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMSTSTEVIAHHWAFAIFLIIAIGLCCLMLVGGWYLGGRARARSKNTPFESGIDSVGSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHCCH
RLRLSAKFYLVAMFFVIFDVEALYLYAWSTSIRESGWVGFVEAAIFILVLLAGLVYLVRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GALDWTPARSRRTLVNPETDSPTNRHMQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MRMSTSTEVIAHHWAFAIFLIIAIGLCCLMLVGGWYLGGRARARSKNTPFESGIDSVGSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHCCH
RLRLSAKFYLVAMFFVIFDVEALYLYAWSTSIRESGWVGFVEAAIFILVLLAGLVYLVRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GALDWTPARSRRTLVNPETDSPTNRHMQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA