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The map label for this gene is lrhA [H]

Identifier: 238895807

GI number: 238895807

Start: 3754202

End: 3755128

Strand: Reverse

Name: lrhA [H]

Synonym: KP1_3924

Alternate gene names: 238895807

Gene position: 3755128-3754202 (Counterclockwise)

Preceding gene: 238895808

Following gene: 238895805

Centisome position: 71.55

GC content: 57.93

Gene sequence:

>927_bases
ATGATTAATACAACACGTCCCATACTCAACCTCGATCTCGATCTGCTGCGTACCTTTGTCGCGGTCGCTGATTTGAACAC
TTTTGCCGCCGCCGCCGCCGCAGTGTGTCGTACTCAGTCCGCGGTCAGTCAGCAAATGCAACGCCTGGAACAGCTGGTGG
GCAAAGAGCTTTTCGCCCGCCACGGCCGCAATAAGCTGCTGACCGAGCAGGGGATCCAGCTGCTGGGCTATGCCCGCAAA
ATTCTCCGTTTTAACGATGAAGCCTGTATGTCGCTGATGTATGGCAGCCTGCAGGGGGCTCTGAGCATCGGTGCGTCAGA
AGAAACGGCTGACACCATCCTGCCGTTTTTGTTAAACCGCATCGGCTGTTTCTATCCCAGAATGACGTTGGAGATCAAAG
TTCACCCCCATGCCGCCATCATGGAGATGTTGGCCGAGGGGCTGGTCGATCTGGCGTTGACCACCCATCAGCCTCCCGGC
TTTACCTCTTTTACCCTGAGAACATCACCTACTCTCTGGTATTGCGCAGCGGAATATGTGCTGGCGAAGGGGGAATCTAT
CCCCCTGATCCTGCTCGAAGAGCCAAGTCCATTCCGCCAGGATATTATCGCCGCGCTGGAAACTGCTCGCGTCAGTTGGC
ATCTGGCCCACGGAGCTTCCTCGCTATCGGGCGTGAAAGCGGCGGTGAAGGCCGGGCTGGGCGTGACGGCGCGCCCGGTC
GAAATGATGAGCCCGGATCTACGCGTGGCTGGCATCAGTGAGGGGTTACCGGCGTTGCCGGACACCCGGTACGTCGTCAG
CTGCAATCCGCGGACGGTGAGCGAACTGCCGCAGGCGATTTTTCAGTCTCTGAGCCAGGAGATCCATCCCTGGGAAACGG
GCACAGCACTTACTCCGGAAGAGGGAGGGAATACCTTGGTTTTGTAA

Upstream 100 bases:

>100_bases
CGCCGTCAGACGGTGAGCACGAGGCTCAGGGAATAGCCGGATACCTGGCGTAAAGCATCAACAAGGCAGGTCAGCGTTAG
CCACCTGTAAGTGAAGAAAG

Downstream 100 bases:

>100_bases
GGGTATTCTTGCTAACAAAGATCACAAAAACTGGTAACAGAATGTAAGTGCCCAAAAAGAGCCTCAGGAGTTGGTTTCCC
CCCTGGCGGCTCTTTTTTTT

Product: LysR family NADH dehydrogenase transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MINTTRPILNLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEQGIQLLGYARK
ILRFNDEACMSLMYGSLQGALSIGASEETADTILPFLLNRIGCFYPRMTLEIKVHPHAAIMEMLAEGLVDLALTTHQPPG
FTSFTLRTSPTLWYCAAEYVLAKGESIPLILLEEPSPFRQDIIAALETARVSWHLAHGASSLSGVKAAVKAGLGVTARPV
EMMSPDLRVAGISEGLPALPDTRYVVSCNPRTVSELPQAIFQSLSQEIHPWETGTALTPEEGGNTLVL

Sequences:

>Translated_308_residues
MINTTRPILNLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEQGIQLLGYARK
ILRFNDEACMSLMYGSLQGALSIGASEETADTILPFLLNRIGCFYPRMTLEIKVHPHAAIMEMLAEGLVDLALTTHQPPG
FTSFTLRTSPTLWYCAAEYVLAKGESIPLILLEEPSPFRQDIIAALETARVSWHLAHGASSLSGVKAAVKAGLGVTARPV
EMMSPDLRVAGISEGLPALPDTRYVVSCNPRTVSELPQAIFQSLSQEIHPWETGTALTPEEGGNTLVL
>Mature_308_residues
MINTTRPILNLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEQGIQLLGYARK
ILRFNDEACMSLMYGSLQGALSIGASEETADTILPFLLNRIGCFYPRMTLEIKVHPHAAIMEMLAEGLVDLALTTHQPPG
FTSFTLRTSPTLWYCAAEYVLAKGESIPLILLEEPSPFRQDIIAALETARVSWHLAHGASSLSGVKAAVKAGLGVTARPV
EMMSPDLRVAGISEGLPALPDTRYVVSCNPRTVSELPQAIFQSLSQEIHPWETGTALTPEEGGNTLVL

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=308, Percent_Identity=65.9090909090909, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=28.2868525896414, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994962, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787806, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790208, Length=160, Percent_Identity=31.25, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788481, Length=261, Percent_Identity=23.3716475095785, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=24.2798353909465, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33467; Mature: 33467

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50931 HTH_LYSR ; PS00436 PEROXIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTTRPILNLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEQGIQLLGYARKILRFNDEACMSLMYGSLQGALSIGASEETADTILPFLLNR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IGCFYPRMTLEIKVHPHAAIMEMLAEGLVDLALTTHQPPGFTSFTLRTSPTLWYCAAEYV
HHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHH
LAKGESIPLILLEEPSPFRQDIIAALETARVSWHLAHGASSLSGVKAAVKAGLGVTARPV
HHCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVAGISEGLPALPDTRYVVSCNPRTVSELPQAIFQSLSQEIHPWETGTALTPE
HHCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EGGNTLVL
CCCCEECC
>Mature Secondary Structure
MINTTRPILNLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEQGIQLLGYARKILRFNDEACMSLMYGSLQGALSIGASEETADTILPFLLNR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IGCFYPRMTLEIKVHPHAAIMEMLAEGLVDLALTTHQPPGFTSFTLRTSPTLWYCAAEYV
HHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHH
LAKGESIPLILLEEPSPFRQDIIAALETARVSWHLAHGASSLSGVKAAVKAGLGVTARPV
HHCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVAGISEGLPALPDTRYVVSCNPRTVSELPQAIFQSLSQEIHPWETGTALTPE
HHCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EGGNTLVL
CCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]