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The map label for this gene is pbpG [H]

Identifier: 238895697

GI number: 238895697

Start: 3625558

End: 3626505

Strand: Reverse

Name: pbpG [H]

Synonym: KP1_3798

Alternate gene names: 238895697

Gene position: 3626505-3625558 (Counterclockwise)

Preceding gene: 238895698

Following gene: 238895694

Centisome position: 69.1

GC content: 60.44

Gene sequence:

>948_bases
ATGCCGAAATTTCGAGTCTCTTTGCTCAGCCTGACCTTGCTGCTGGCTGTGCCTTTTGCGCCCCAGGCGTTAGCAAAAAC
CCCGACGGCGGTGACCGCCTCGCAGCCGGAAATTGCCTCCGGCAGCGCCATGATCGTCGATCTGGCCACGAAAAAAATCA
TTTATGCCAGCCAGCCTGATCTGGTGCGCCCGATGGCGTCGATCACCAAAGTGATGACCGCCATGGTGGTGCTCGATGCC
CATCTGCCGCTGGATGAGATGCTGACGGTGGATATCAGCCATACGCCGGAAATGAAGGGGATCTACTCCCGCGTGCGCCT
CAACAGCCAGATTAGTCGCCGCGATATGCTGCTGCTGGCGCTGATGTCTTCCGAGAACCGCGCGGCCGCCAGCCTGGCGC
ATCACTATCCGGGCGGCTACGACGCTTTTATTCGCGCGATGAACGCCAAAGCCCAGGCGCTGGGCATGACCCATACCCGC
TACGTGGAGCCCACCGGCCTGTCGGTGCATAACGTCTCCACCGCCCGCGATCTGACCAAACTGCTGATCGCCAGCGAGCA
GTATCCGCTGATCGGCCAGCTGAGCACCACCAAAGAAGAGACCGCCACCTTCGCCCATCCGGCCTACAGCCTGCCGTTCC
GCAACACCAACCATCTGGTGTATCGCGATAACTGGAACATTCAGCTGACCAAAACCGGCTTCACCAACGCTGCCGGCCAC
TGCCTGATTATGCGCACGGTGATTAACCAACGTCCGGTGGCGCTGGTGGTGATGGATGCCTTCGGCAAATATACCCACTT
CGCTGACGCCAGCCGCTTGCGGACCTGGATTGAAACCGGGAAGGTGATGCCGGTACCCGCCTCGGCGCTGAGCTATAAAA
AGCAGCGCGAAGCGCAGATGGCGGAGGCGATGCTGAAAGGCGGCGCGCAGACCGCGCAGAACGATTAA

Upstream 100 bases:

>100_bases
CCTTACGGCGCGGTATGATGGCGTTTGCCAGCGAAGTTGCCCACTTAACCTCGCGGCGTACGTTCCATAACGTGCAAAAA
TACTTTTCAGAATGCCCATG

Downstream 100 bases:

>100_bases
TCTGCATGTCTCCCGGATGGCGGCGCATTGCGCCTTATCCGGGCTACGTGATTTGGCACCGGGTTCGCCCCTTTCGTAGG
CCCGGCAAGCGCAGCGCCGC

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPKFRVSLLSLTLLLAVPFAPQALAKTPTAVTASQPEIASGSAMIVDLATKKIIYASQPDLVRPMASITKVMTAMVVLDA
HLPLDEMLTVDISHTPEMKGIYSRVRLNSQISRRDMLLLALMSSENRAAASLAHHYPGGYDAFIRAMNAKAQALGMTHTR
YVEPTGLSVHNVSTARDLTKLLIASEQYPLIGQLSTTKEETATFAHPAYSLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
CLIMRTVINQRPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPASALSYKKQREAQMAEAMLKGGAQTAQND

Sequences:

>Translated_315_residues
MPKFRVSLLSLTLLLAVPFAPQALAKTPTAVTASQPEIASGSAMIVDLATKKIIYASQPDLVRPMASITKVMTAMVVLDA
HLPLDEMLTVDISHTPEMKGIYSRVRLNSQISRRDMLLLALMSSENRAAASLAHHYPGGYDAFIRAMNAKAQALGMTHTR
YVEPTGLSVHNVSTARDLTKLLIASEQYPLIGQLSTTKEETATFAHPAYSLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
CLIMRTVINQRPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPASALSYKKQREAQMAEAMLKGGAQTAQND
>Mature_314_residues
PKFRVSLLSLTLLLAVPFAPQALAKTPTAVTASQPEIASGSAMIVDLATKKIIYASQPDLVRPMASITKVMTAMVVLDAH
LPLDEMLTVDISHTPEMKGIYSRVRLNSQISRRDMLLLALMSSENRAAASLAHHYPGGYDAFIRAMNAKAQALGMTHTRY
VEPTGLSVHNVSTARDLTKLLIASEQYPLIGQLSTTKEETATFAHPAYSLPFRNTNHLVYRDNWNIQLTKTGFTNAAGHC
LIMRTVINQRPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPASALSYKKQREAQMAEAMLKGGAQTAQND

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=292, Percent_Identity=85.6164383561644, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1787062, Length=275, Percent_Identity=29.8181818181818, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082022, Length=273, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786851, Length=289, Percent_Identity=25.9515570934256, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 34554; Mature: 34422

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKFRVSLLSLTLLLAVPFAPQALAKTPTAVTASQPEIASGSAMIVDLATKKIIYASQPD
CCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCCCEEEEEECCCEEEEECCCH
LVRPMASITKVMTAMVVLDAHLPLDEMLTVDISHTPEMKGIYSRVRLNSQISRRDMLLLA
HHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCHHHHHHHHHHCCHHHHHHEEEEE
LMSSENRAAASLAHHYPGGYDAFIRAMNAKAQALGMTHTRYVEPTGLSVHNVSTARDLTK
EECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCEEECCHHHHHHHH
LLIASEQYPLIGQLSTTKEETATFAHPAYSLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
HHHCCCCCCCEECCCCCHHHHHHCCCCCEECCCCCCCEEEEECCCEEEEEECCCCCCCCH
CLIMRTVINQRPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPASALSYKKQREAQM
HEEEEHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AEAMLKGGAQTAQND
HHHHHHCCCCCCCCC
>Mature Secondary Structure 
PKFRVSLLSLTLLLAVPFAPQALAKTPTAVTASQPEIASGSAMIVDLATKKIIYASQPD
CCHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCCCEEEEEECCCEEEEECCCH
LVRPMASITKVMTAMVVLDAHLPLDEMLTVDISHTPEMKGIYSRVRLNSQISRRDMLLLA
HHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCHHHHHHHHHHCCHHHHHHEEEEE
LMSSENRAAASLAHHYPGGYDAFIRAMNAKAQALGMTHTRYVEPTGLSVHNVSTARDLTK
EECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCEEECCHHHHHHHH
LLIASEQYPLIGQLSTTKEETATFAHPAYSLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
HHHCCCCCCCEECCCCCHHHHHHCCCCCEECCCCCCCEEEEECCCEEEEEECCCCCCCCH
CLIMRTVINQRPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPASALSYKKQREAQM
HEEEEHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AEAMLKGGAQTAQND
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]