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The map label for this gene is yicO [H]

Identifier: 238895681

GI number: 238895681

Start: 3606645

End: 3607988

Strand: Direct

Name: yicO [H]

Synonym: KP1_3778

Alternate gene names: 238895681

Gene position: 3606645-3607988 (Clockwise)

Preceding gene: 238895680

Following gene: 238895683

Centisome position: 68.72

GC content: 62.8

Gene sequence:

>1344_bases
ATGGCCGATAACACACTTCACTCTTCCGCCCGCGCTAACTGGCTGGAGCGCCGCTTTGCGCTGCGCTCGCGCGGCGGCAC
GCTACGCACCGAATGCCTGGCCGGGATCACCGGTTTCCTCGCCGCCGCCTATTTACTGGTGGTCATCCCGGGGCTGCTGG
CGATCGGCGGGATGGATAAAGGCGCCGCCACCACCGGCACCATTCTGGTCTTCGTCGTCGGCTCGCTGCTGATGGCGTTT
TATGCCAACCTGCCGTTTATCGTCGGCCCGGGCATTGGCGGCTCGGTGCTGGTGGGGGTGACGCTGGCTGGTAGCGAAGG
GATTGGCTGGCAGACTGGCCTCGGAATTGCCTGCTGGTCGGGGATCCTCTTCTTCCTGCTGACCCGCTTTGGCCTGCGCG
AAGTGGTCACCCGCTCGGTGCCGCAGTCGATCAAGCTGGGATTGACGGCCTCCATCGGCCTGTTTGTCACCGTCCTCGGT
TTTCGCAATGCCGGGCTGGTGCTGGCCAATGCGAAAACCAACGCCCTGATGCTCGGCGACTTTCTCGCCCCCGGCGCGCT
GGTGGCGCTGTGCGGCCTGTTCCTGGCGATAGCCCTGCAGGCGCGTAAGGTTCCGGGCGCCATTTTGTGGGCCATTCTGT
GCGCTACCCTGGTGGGTATCCCGTTCGGCGTGACTAAACTGCCGACGCATTTTATCGATGCCCCCCACTCGCTGGCGCCG
GTGCTGGGACAGGTTGACCTGCTGGGGGCGTTAAACATCGCCTTCCTGCCGTTCCTGTTCGTCTTTTTCGCATCTGAGTT
TTTCTCCACCATGGGGACAACGCTGGCGGTGGGCGGCGAGGCGGGTCTGCTGGATGAAGAAGGCAACATGCCGCAGATTA
ATCGCCCGTTCATGGTCGATTCGATTGCCGCCGCGCTCGGCCCGTGGGTGGGCATTCCGGCGGCGACGGCGCTGATTGAA
TCTTCGGCGGCAGCGGAAGCGGGCGGCAAAACCGGCCTCACCGCCCTGTCGGCGGCGGTAATGTTCCTGCTGATGCTGCT
GTTCACGCCGGTGGCGTTGATGATCCCGAAAGAAGCCACCGCCCCGGCGCTGATCCTGATTGGCCTGAACATGTTCAGCG
GCCTGCGCAAAGTGGATCTTGCCAACTTCACCGACGGGCTGCCGGTGCTGATGATGGTGATGATCACCCTTATCGCCAAC
AGCTTTGGCACCGGGATTGCCGGCGGGCTGCTGTTTTACATTGTGATCAAGGCTATCGCCGGTAAGTGGCGGGAGATCCC
GATTGGCCTGTGGGTATTGGCCGTCCCGCTGGTGTATTACTTCGCGACCTTAGTCAGGCATTAA

Upstream 100 bases:

>100_bases
TGACCGACGGCGGCAGCCGCCAGATAGTCGACCCGTTGATAGCCTGCCGGGAGATCCCGGAGCCAACCGATCACAACAAT
AATCCTCAGGGAGCCTGAGC

Downstream 100 bases:

>100_bases
GCCCTTCACAATGTGATTTCACCTCTTCATATAACAAACGCACCGCGGCAGAGAGCTGTTTGCGGTGCGGACAAATCAGA
TTCAACGGCACTACATCCCC

Product: putative xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MADNTLHSSARANWLERRFALRSRGGTLRTECLAGITGFLAAAYLLVVIPGLLAIGGMDKGAATTGTILVFVVGSLLMAF
YANLPFIVGPGIGGSVLVGVTLAGSEGIGWQTGLGIACWSGILFFLLTRFGLREVVTRSVPQSIKLGLTASIGLFVTVLG
FRNAGLVLANAKTNALMLGDFLAPGALVALCGLFLAIALQARKVPGAILWAILCATLVGIPFGVTKLPTHFIDAPHSLAP
VLGQVDLLGALNIAFLPFLFVFFASEFFSTMGTTLAVGGEAGLLDEEGNMPQINRPFMVDSIAAALGPWVGIPAATALIE
SSAAAEAGGKTGLTALSAAVMFLLMLLFTPVALMIPKEATAPALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIAN
SFGTGIAGGLLFYIVIKAIAGKWREIPIGLWVLAVPLVYYFATLVRH

Sequences:

>Translated_447_residues
MADNTLHSSARANWLERRFALRSRGGTLRTECLAGITGFLAAAYLLVVIPGLLAIGGMDKGAATTGTILVFVVGSLLMAF
YANLPFIVGPGIGGSVLVGVTLAGSEGIGWQTGLGIACWSGILFFLLTRFGLREVVTRSVPQSIKLGLTASIGLFVTVLG
FRNAGLVLANAKTNALMLGDFLAPGALVALCGLFLAIALQARKVPGAILWAILCATLVGIPFGVTKLPTHFIDAPHSLAP
VLGQVDLLGALNIAFLPFLFVFFASEFFSTMGTTLAVGGEAGLLDEEGNMPQINRPFMVDSIAAALGPWVGIPAATALIE
SSAAAEAGGKTGLTALSAAVMFLLMLLFTPVALMIPKEATAPALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIAN
SFGTGIAGGLLFYIVIKAIAGKWREIPIGLWVLAVPLVYYFATLVRH
>Mature_446_residues
ADNTLHSSARANWLERRFALRSRGGTLRTECLAGITGFLAAAYLLVVIPGLLAIGGMDKGAATTGTILVFVVGSLLMAFY
ANLPFIVGPGIGGSVLVGVTLAGSEGIGWQTGLGIACWSGILFFLLTRFGLREVVTRSVPQSIKLGLTASIGLFVTVLGF
RNAGLVLANAKTNALMLGDFLAPGALVALCGLFLAIALQARKVPGAILWAILCATLVGIPFGVTKLPTHFIDAPHSLAPV
LGQVDLLGALNIAFLPFLFVFFASEFFSTMGTTLAVGGEAGLLDEEGNMPQINRPFMVDSIAAALGPWVGIPAATALIES
SAAAEAGGKTGLTALSAAVMFLLMLLFTPVALMIPKEATAPALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIANS
FGTGIAGGLLFYIVIKAIAGKWREIPIGLWVLAVPLVYYFATLVRH

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=435, Percent_Identity=35.4022988505747, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1790150, Length=429, Percent_Identity=34.4988344988345, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1790499, Length=443, Percent_Identity=34.3115124153499, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI48994909, Length=436, Percent_Identity=32.3394495412844, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46576; Mature: 46445

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNTLHSSARANWLERRFALRSRGGTLRTECLAGITGFLAAAYLLVVIPGLLAIGGMDK
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAATTGTILVFVVGSLLMAFYANLPFIVGPGIGGSVLVGVTLAGSEGIGWQTGLGIACWS
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHH
GILFFLLTRFGLREVVTRSVPQSIKLGLTASIGLFVTVLGFRNAGLVLANAKTNALMLGD
HHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEHH
FLAPGALVALCGLFLAIALQARKVPGAILWAILCATLVGIPFGVTKLPTHFIDAPHSLAP
HHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCHHHHH
VLGQVDLLGALNIAFLPFLFVFFASEFFSTMGTTLAVGGEAGLLDEEGNMPQINRPFMVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHH
SIAAALGPWVGIPAATALIESSAAAEAGGKTGLTALSAAVMFLLMLLFTPVALMIPKEAT
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIANSFGTGIAGGLLFYIVIKAIA
CCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GKWREIPIGLWVLAVPLVYYFATLVRH
CCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADNTLHSSARANWLERRFALRSRGGTLRTECLAGITGFLAAAYLLVVIPGLLAIGGMDK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAATTGTILVFVVGSLLMAFYANLPFIVGPGIGGSVLVGVTLAGSEGIGWQTGLGIACWS
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHH
GILFFLLTRFGLREVVTRSVPQSIKLGLTASIGLFVTVLGFRNAGLVLANAKTNALMLGD
HHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEHH
FLAPGALVALCGLFLAIALQARKVPGAILWAILCATLVGIPFGVTKLPTHFIDAPHSLAP
HHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCHHHHH
VLGQVDLLGALNIAFLPFLFVFFASEFFSTMGTTLAVGGEAGLLDEEGNMPQINRPFMVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHH
SIAAALGPWVGIPAATALIESSAAAEAGGKTGLTALSAAVMFLLMLLFTPVALMIPKEAT
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIANSFGTGIAGGLLFYIVIKAIA
CCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GKWREIPIGLWVLAVPLVYYFATLVRH
CCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]