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The map label for this gene is ade [H]

Identifier: 238895680

GI number: 238895680

Start: 3604789

End: 3606642

Strand: Direct

Name: ade [H]

Synonym: KP1_3777

Alternate gene names: 238895680

Gene position: 3604789-3606642 (Clockwise)

Preceding gene: 238895678

Following gene: 238895681

Centisome position: 68.68

GC content: 65.64

Gene sequence:

>1854_bases
GTGCCCCTAGAGTATCCGCATTATCCTTGTGCCGGAGTGGTTATGTCCAGCAATGCTCAAGTCCGCCGTCGCGCCGTGCA
GGCCGCGCGCGGTGAATCCCCGTTTGATCTGCTGCTGATCGATGCGCAGATCGTCGATATGGCCACGGGCGAAATTCGCC
CCGCTGACGTCGGTATCGTCGGCGAGATGATCGCCAGCGTCCACCCGCGCGGCAGTCGCGAAGACGCCCATGAAGTGCGT
TCCCTGGCCGGTGGCTACCTGTCCCCCGGCCTGATGGACACCCACGTGCATCTCGAAAGCTCGCACCTGCCGCCGGAGCG
CTATGCGGAAATCGTCCTCACCCAGGGCACCACCGCAGTGTTCTGGGATCCGCATGAGCTGGCCAACGTCCTCGGCGTCG
CTGGCGTGCGCTATGCGGTGGACGCCAGCCGCCATCTGCCGCTGCAGGTGATGGTCGCCGCGCCGTCCAGCGTCCCCTCC
ACGCCGGGTCTCGAAATGTCCGGCGCTGATTTCGCCGGCGAGGAGATGGAGACCATGCTCGGCTGGCCGGAAGTGCGCGG
CGTGGCGGAGGTGATGGATATGCACGGCGTGCTGCACGGTAGCGAGCGGATGCAGGAGATTGTCCAGGCCGGTCTCAACA
GCGGCAAACTGATTGAAGGCCACGCCCGCGGCCTGAGCGGCGCTGACCTGCAGGCCTACCTCGCCGCCGGCGTCACCTCC
GATCACGAACTGACCTCGGCGGACGACGCGCTGGAAAAACTGCGCGCCGGGCTGACGATCGAGATCCGCGGCTCGCACCC
CTATCTGCTGCCGGATATCGTCGCGGCGTTAAAAACGCTGCCGCACCTCTCCTCGCAGATCACCGTCTGCACCGATGACG
TGCCGCCGGATATACTACTGGAGAAAGGCGGCATCATCGCCCTGCTTAATCTGCTGATCGAGCACGGTTTACCGGCGGTC
GATGCGCTGCGATTCGCCACCCTCAACGCCGCTATTCGCCTGCAGCGCCACGATCTTGGGCTGATTGCCGCCGGGCGGCG
CGCCGATCTGGTGGTGTTTGATTCCCTGGAGAAACTGGTGGCCCGCGAAGTCTACGTAGGCGGTAAGCTGCTGGCCCGCG
CGGGCAACCTGCTGACACCGATCGCGCCCGCCGCGGGCGTCACGCCGCCGCGCGATACTTTGCAGATCGCCCCCCTCCGC
GCCGATGACTTTATTCTGCGCGTCCAGGGCATTCGTCACGGCATCGCCCGCCTGCGCCATATCCGCGGCGCGCGCTTCAC
CCAGTGGGGCGAAGTGGAAGTGCAGGTTCGTGACGGGAAAGTCCAGCTGCCCGCCGGCTTCAGTCTGATCTGGGTCAAGC
ACCGCCACGGCCGCCATCAGGCGACGCCGCAAATCGCCCTGCTTGAAGGCTGGGGTGAGCTGCACGGCGCCATCGCCACC
AGCTACTCCCACGACTCGCATAATCTGGTGGTGCTCGGGCGCGACGCTAATGATATGGCGCTGGCGGCCAACCAGCTTAT
CGCCTCCGGCGGCGGGATGGCGCTGGCGCAACAGGGCGAGATCCTTGCCCATGTGGCGATGCCGATTGCCGGCATGCTGT
CGGATCTCCCGGCCGCGGAACTGGCGCGTCAGTTCCGCGAGCTGCGCGATCTGAGCAGCCAAGTCGCCGACTGGGAGCCG
CCGTACCGGGTCTTCAAGGCCATTGAAGGCACCTGCCTTGCCTGTAACGCCGGGCCGCATTTAACCGATTTGGGTCTGAC
CGACGGCGGCAGCCGCCAGATAGTCGACCCGTTGATAGCCTGCCGGGAGATCCCGGAGCCAACCGATCACAACAATAATC
CTCAGGGAGCCTGA

Upstream 100 bases:

>100_bases
GCTGCCAGGGTTCGTTCATCATCGGGTTCGCTACGGTGGTCCTGCACAATAACCCGAGCTTATCGGGTGATAAATTTATT
CATCTGGGCAAACGTTTGCT

Downstream 100 bases:

>100_bases
GCATGGCCGATAACACACTTCACTCTTCCGCCCGCGCTAACTGGCTGGAGCGCCGCTTTGCGCTGCGCTCGCGCGGCGGC
ACGCTACGCACCGAATGCCT

Product: putative amidohydrolase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MPLEYPHYPCAGVVMSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSREDAHEVR
SLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPS
TPGLEMSGADFAGEEMETMLGWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTS
DHELTSADDALEKLRAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIEHGLPAV
DALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLVAREVYVGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLR
ADDFILRVQGIRHGIARLRHIRGARFTQWGEVEVQVRDGKVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELHGAIAT
SYSHDSHNLVVLGRDANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQVADWEP
PYRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNPQGA

Sequences:

>Translated_617_residues
MPLEYPHYPCAGVVMSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSREDAHEVR
SLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPS
TPGLEMSGADFAGEEMETMLGWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTS
DHELTSADDALEKLRAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIEHGLPAV
DALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLVAREVYVGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLR
ADDFILRVQGIRHGIARLRHIRGARFTQWGEVEVQVRDGKVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELHGAIAT
SYSHDSHNLVVLGRDANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQVADWEP
PYRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNPQGA
>Mature_616_residues
PLEYPHYPCAGVVMSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSREDAHEVRS
LAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPST
PGLEMSGADFAGEEMETMLGWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTSD
HELTSADDALEKLRAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIEHGLPAVD
ALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLVAREVYVGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLRA
DDFILRVQGIRHGIARLRHIRGARFTQWGEVEVQVRDGKVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELHGAIATS
YSHDSHNLVVLGRDANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQVADWEPP
YRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNPQGA

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=576, Percent_Identity=31.9444444444444, Blast_Score=237, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 66104; Mature: 65973

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLEYPHYPCAGVVMSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIV
CCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCHHH
GEMIASVHPRGSREDAHEVRSLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAV
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHEEEEECCCEEE
FWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGEEMETML
EECHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
GWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHCCCCCCCCHHHHHHHCCCC
DHELTSADDALEKLRAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILL
CCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEE
EKGGIIALLNLLIEHGLPAVDALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLV
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCEEECCCCCCEEEHHHHHHHH
AREVYVGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHGIARLRH
HHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHH
IRGARFTQWGEVEVQVRDGKVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELHGAIAT
HCCCCCCCCCEEEEEEECCEEECCCCCEEEEEEECCCCCCCCCCEEEEECHHHHHHHHHC
SYSHDSHNLVVLGRDANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAE
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHH
LARQFRELRDLSSQVADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIA
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHH
CREIPEPTDHNNNPQGA
HHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLEYPHYPCAGVVMSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIV
CCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCHHH
GEMIASVHPRGSREDAHEVRSLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAV
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHEEEEECCCEEE
FWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGEEMETML
EECHHHHHHHHHHCCHHEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
GWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEHHCCCCCCCCHHHHHHHCCCC
DHELTSADDALEKLRAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILL
CCCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEE
EKGGIIALLNLLIEHGLPAVDALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLV
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCEEECCCCCCEEEHHHHHHHH
AREVYVGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHGIARLRH
HHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHH
IRGARFTQWGEVEVQVRDGKVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELHGAIAT
HCCCCCCCCCEEEEEEECCEEECCCCCEEEEEEECCCCCCCCCCEEEEECHHHHHHHHHC
SYSHDSHNLVVLGRDANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAE
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHH
LARQFRELRDLSSQVADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIA
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHH
CREIPEPTDHNNNPQGA
HHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA