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The map label for this gene is wzb [H]

Identifier: 238895630

GI number: 238895630

Start: 3540544

End: 3540978

Strand: Reverse

Name: wzb [H]

Synonym: KP1_3719

Alternate gene names: 238895630

Gene position: 3540978-3540544 (Counterclockwise)

Preceding gene: 238895631

Following gene: 238895629

Centisome position: 67.47

GC content: 35.63

Gene sequence:

>435_bases
ATGTTTAAATCAGTTTTAGTTGTTTGTATTGGAAATGTTTGCAGATCACCAACTGGCGAAATGTTGCTGAAAAAAAGACT
GAAAGATTTCAAGATCGGTTCTGCAGGACTCGGTGCTTTAGTTAACCATCCAGCGGACGCTACAGCAAAAAAGGTCGCCT
TTGAGAACAATTTAGATCTTGATCAACACATTGCAAGACAAGTAACTAAAGATATTTGTAAAGAATATGATTTAATACTT
GTTATGGAAAAAAAACATATAGACCTAATATGTAAACTAGCTCCGGAATTACGTGGCAAAACTATGTTATTCGGACATTG
GATAGGGCAACGAGAAATAGCCGATCCATATATGAAAAGTAAAGAAGCGTTCGAATCTGTATATAAACTTCTCGACGAAT
CAGCTCAAAAATGGGCAGACGTCTTAATTAAATAG

Upstream 100 bases:

>100_bases
GTAGTACGTTGGAACCGTGTAGTCTCTCAATTGGTTCCAACTATTACCGGGGTACATGATATGACAGAAGCCGCGAGATA
TGTAAGGAACTGGTAACCAT

Downstream 100 bases:

>100_bases
TGCAGGGTATCAGATGACTGATAAACTTAATTCAATGTCTACAGGAAGCCAAGAAAGTGACGGGATCGATCTAGGTCGTT
TAATTGGTGAAGTTATTGAT

Product: putative protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MFKSVLVVCIGNVCRSPTGEMLLKKRLKDFKIGSAGLGALVNHPADATAKKVAFENNLDLDQHIARQVTKDICKEYDLIL
VMEKKHIDLICKLAPELRGKTMLFGHWIGQREIADPYMKSKEAFESVYKLLDESAQKWADVLIK

Sequences:

>Translated_144_residues
MFKSVLVVCIGNVCRSPTGEMLLKKRLKDFKIGSAGLGALVNHPADATAKKVAFENNLDLDQHIARQVTKDICKEYDLIL
VMEKKHIDLICKLAPELRGKTMLFGHWIGQREIADPYMKSKEAFESVYKLLDESAQKWADVLIK
>Mature_144_residues
MFKSVLVVCIGNVCRSPTGEMLLKKRLKDFKIGSAGLGALVNHPADATAKKVAFENNLDLDQHIARQVTKDICKEYDLIL
VMEKKHIDLICKLAPELRGKTMLFGHWIGQREIADPYMKSKEAFESVYKLLDESAQKWADVLIK

Specific function: May function as a phosphatase required for amylovoran (an exopolysaccharide that functions as a virulence factor) production [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=139, Percent_Identity=30.2158273381295, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1788375, Length=142, Percent_Identity=56.3380281690141, Blast_Score=182, Evalue=9e-48,
Organism=Escherichia coli, GI87081812, Length=143, Percent_Identity=53.8461538461538, Blast_Score=160, Evalue=4e-41,
Organism=Drosophila melanogaster, GI78706766, Length=140, Percent_Identity=32.8571428571429, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI78706768, Length=140, Percent_Identity=32.8571428571429, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16274; Mature: 16274

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSVLVVCIGNVCRSPTGEMLLKKRLKDFKIGSAGLGALVNHPADATAKKVAFENNLDL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCH
DQHIARQVTKDICKEYDLILVMEKKHIDLICKLAPELRGKTMLFGHWIGQREIADPYMKS
HHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHCCHHHHH
KEAFESVYKLLDESAQKWADVLIK
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFKSVLVVCIGNVCRSPTGEMLLKKRLKDFKIGSAGLGALVNHPADATAKKVAFENNLDL
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHCCCCCCH
DQHIARQVTKDICKEYDLILVMEKKHIDLICKLAPELRGKTMLFGHWIGQREIADPYMKS
HHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHCCHHHHH
KEAFESVYKLLDESAQKWADVLIK
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7596293 [H]