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The map label for this gene is sbmC [H]

Identifier: 238895588

GI number: 238895588

Start: 3490293

End: 3490766

Strand: Reverse

Name: sbmC [H]

Synonym: KP1_3671

Alternate gene names: 238895588

Gene position: 3490766-3490293 (Counterclockwise)

Preceding gene: 238895589

Following gene: 238895587

Centisome position: 66.51

GC content: 60.55

Gene sequence:

>474_bases
ATGAACTACAGCATTACCACCCTCGGCAAGAAAACCATCGCCGGTTTCCATCTGGTCGGGCCCTGGGATCACACGGTCAA
GCAGGGGTTTGAGCAACTGATGATGTGGGTTGAGAACCACCAGGTGCCCGCCCGCGAATGGGTGGCCGTCTACTACGATA
ACCCGGAGGAAGTGCCGGCGGAAAAACTGCGCTGCGCGACGGCGGTCACCGTGGATGAGGATTATGTCATTCCCGCCAAC
AGCGAAGGGGTGATCCTGGCGGCGATTGCCGGCGGGGATTACGCCTGCGCCCGCGCGCGGGTGGTGGATTACGACTTCGC
CACCCCGTGGATGCAGTTTTTTGACAGCCTGCAGCAGAGCACGGCGTATCGCATCGCCCCCCAGCCCTGCTTTGAGGTCT
ATCTTAACGACGGCAACCACGACGGCTACTGGGATATCGACATGTATGTTCCCGTTGAGCGCGTCGCGTCGTAG

Upstream 100 bases:

>100_bases
GTGTGGTGGCGACTCTGTGAATTCGCGCACATACTGAGGGGGGATCTCCTGTTAAATTAACTGTATATTCATACAGTAAT
TTATCTCCAAAGGAGGCAAG

Downstream 100 bases:

>100_bases
CAGTTTACCCCTGTTCCGGACAAGGTTTTTTACATTCCCGGCATGCTCCGGGCGAAAAAGCAGTTACAATTGGCCTTTTC
GTTTTGCCGGAGAGGGTTGT

Product: DNA gyrase inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNYSITTLGKKTIAGFHLVGPWDHTVKQGFEQLMMWVENHQVPAREWVAVYYDNPEEVPAEKLRCATAVTVDEDYVIPAN
SEGVILAAIAGGDYACARARVVDYDFATPWMQFFDSLQQSTAYRIAPQPCFEVYLNDGNHDGYWDIDMYVPVERVAS

Sequences:

>Translated_157_residues
MNYSITTLGKKTIAGFHLVGPWDHTVKQGFEQLMMWVENHQVPAREWVAVYYDNPEEVPAEKLRCATAVTVDEDYVIPAN
SEGVILAAIAGGDYACARARVVDYDFATPWMQFFDSLQQSTAYRIAPQPCFEVYLNDGNHDGYWDIDMYVPVERVAS
>Mature_157_residues
MNYSITTLGKKTIAGFHLVGPWDHTVKQGFEQLMMWVENHQVPAREWVAVYYDNPEEVPAEKLRCATAVTVDEDYVIPAN
SEGVILAAIAGGDYACARARVVDYDFATPWMQFFDSLQQSTAYRIAPQPCFEVYLNDGNHDGYWDIDMYVPVERVAS

Specific function: Inhibits the supercoiling activity of DNA gyrase. Protects cells from the DNA replication inhibitor microcin B17 (MccB17). Blocks MccB17 export from producing cells [H]

COG id: COG3449

COG function: function code L; DNA gyrase inhibitor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788319, Length=153, Percent_Identity=65.359477124183, Blast_Score=216, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind [H]

EC number: NA

Molecular weight: Translated: 17791; Mature: 17791

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSITTLGKKTIAGFHLVGPWDHTVKQGFEQLMMWVENHQVPAREWVAVYYDNPEEVPA
CCCEEEECCCHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCH
EKLRCATAVTVDEDYVIPANSEGVILAAIAGGDYACARARVVDYDFATPWMQFFDSLQQS
HHHHEEEEEEECCCEEEECCCCCEEEEEEECCCEEEHEEEEEECCCCCHHHHHHHHHHHC
TAYRIAPQPCFEVYLNDGNHDGYWDIDMYVPVERVAS
CEEEECCCCEEEEEEECCCCCCEEEEEEECCHHHHCC
>Mature Secondary Structure
MNYSITTLGKKTIAGFHLVGPWDHTVKQGFEQLMMWVENHQVPAREWVAVYYDNPEEVPA
CCCEEEECCCHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCH
EKLRCATAVTVDEDYVIPANSEGVILAAIAGGDYACARARVVDYDFATPWMQFFDSLQQS
HHHHEEEEEEECCCEEEECCCCCEEEEEEECCCEEEHEEEEEECCCCCHHHHHHHHHHHC
TAYRIAPQPCFEVYLNDGNHDGYWDIDMYVPVERVAS
CEEEECCCCEEEEEEECCCCCCEEEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]