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The map label for this gene is yeeO [H]

Identifier: 238895506

GI number: 238895506

Start: 3394131

End: 3395600

Strand: Reverse

Name: yeeO [H]

Synonym: KP1_3579

Alternate gene names: 238895506

Gene position: 3395600-3394131 (Counterclockwise)

Preceding gene: 238895508

Following gene: 238895504

Centisome position: 64.7

GC content: 59.25

Gene sequence:

>1470_bases
ATGTTGTTTCAACATTTCTCACTAAGGTCTCTCTTGAACGTCACCTCCGCCGTACGCCAGGCCGTCGAACGGACATCCTG
GTTTAAAAAACGTCAGCGTTATCGTGTGCTGTACTGGCGCGAAATCAGCCCTCTCGCTGTGCCCATTCTGCTGGAAAATG
CCTGTGTGCTGCTGATGGGGGTGTTGAGCACCTTCCTTGTCAGCTGGCTGGGAAAAGAGGCCATGGCCGGAGTGGGGCTG
GCCGATAGCTTTAACATGGTCATCATGTCCTTCTTTGCCGCCATCGATTTGGGCACCACGGTGGTGGTGGCCTTTAGCCT
CGGCAAGCGCGATCGGCGGCGAGCGAGAGCGGCCGCGCGCCAGTCGCTGGCCATTATGACCCTGTTTTCCATTTTGCTGG
CGGGGGTGATCCATGCCTTTGGCCAGGAGATTATTGATTTTGTCGCCGGCGATGCCACCGCCCAGGTCAAGGACCTGGCG
CTGACCTATCTGGAACTGACGGCGCTGAGCTACCCGGCGGCGGCGATTGCGTTGATCGGCAGCGGGGCGCTGCGCGGCGC
CGGCACCACCAAAATCCCGCTGCTGATCAACGGCGGGATGAACATTCTCAATATCTTAATCAGCAGCGTGCTCATCTACG
GCATCTTCTCCTGGCCGGGGCTGGGGTTTGTCGGCGCCGGGCTTGGGCTGACCATTGCCCGCTATATTGGCGCGATAGCC
ACGATCTGGGTGCTGATGGTGGGCCTCAATCCGGCGCTGCGGCTGTCGCTGAAGGGCTACTTCAAACCCTTTAACTTCGC
CATTATCTGGGAGGTGATGGGGATCGGCATCCCGGCCAGTATCGAATCGGTCCTGTTCAATGGCGGCAAGCTGCTGACCC
AGATGTTTGTCGCCGGGATGGGCACCAACGTTATCGCCGGCAACTTTATCGCCTTTTCGGTGGCCTCGCTAATTAACCTG
CCGGGCAACGCCCTCGGCTCTGCCTCGACGATCATTACCGGCAAGCGGCTGGGAAAAGGGCAGATTGGTCAGGCTGAATT
CCAGGCCTGGCACGTATTTTGGCTGTCGACGATCATTCTGACGCTGATCGCCTGGGGCAGCGCCCCCTTCGCCGGCTTTA
TCGCCTCGTTCTACACCCATGAAGAAGATGTAAAAGAAGTGGTTAAACAGCTGCTGTGGCTCAACGCCCTGTTTATGCCG
ATCTGGTCGCTGTCGTGGACTTTACCCTGCGCTTTTAAAGGCGCCCGTGACGTACGCTACACCATGTGGGTGTCGATGCT
CGGCATGTGGGGCTGCCGGGTGGTGGCGGGCTATACCCTGGGCATCGTGCTGGGGATGGGGGTGATTGGCGTCTGGTTAG
GGATGGTGCTCGACTGGGCGGTGCGCGGCGTGCTGTTTTATTTCCGCATGGTGAGCGGGCGCTGGCTGTGGAAATACCCG
CGCGTGAAGGCTTCGTCGGAGGAAAGCTGA

Upstream 100 bases:

>100_bases
TCAGGTGCAACTGCCGCTTACATCGACAATTTGTTGTCATTTCCGACAATTATTACGGAAAATACTTTGCAGGATATCCA
TTTCTCAATCATCATTTGAA

Downstream 100 bases:

>100_bases
GCCGTATGCGAGGCTAAACGCCATTTTTTGCGCAAAGTGAAGAATAATTCGGCAAACGATTCATTTTATTGAAAACAGGC
TTTGACAGCGCCGGGCGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLFQHFSLRSLLNVTSAVRQAVERTSWFKKRQRYRVLYWREISPLAVPILLENACVLLMGVLSTFLVSWLGKEAMAGVGL
ADSFNMVIMSFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLAIMTLFSILLAGVIHAFGQEIIDFVAGDATAQVKDLA
LTYLELTALSYPAAAIALIGSGALRGAGTTKIPLLINGGMNILNILISSVLIYGIFSWPGLGFVGAGLGLTIARYIGAIA
TIWVLMVGLNPALRLSLKGYFKPFNFAIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVASLINL
PGNALGSASTIITGKRLGKGQIGQAEFQAWHVFWLSTIILTLIAWGSAPFAGFIASFYTHEEDVKEVVKQLLWLNALFMP
IWSLSWTLPCAFKGARDVRYTMWVSMLGMWGCRVVAGYTLGIVLGMGVIGVWLGMVLDWAVRGVLFYFRMVSGRWLWKYP
RVKASSEES

Sequences:

>Translated_489_residues
MLFQHFSLRSLLNVTSAVRQAVERTSWFKKRQRYRVLYWREISPLAVPILLENACVLLMGVLSTFLVSWLGKEAMAGVGL
ADSFNMVIMSFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLAIMTLFSILLAGVIHAFGQEIIDFVAGDATAQVKDLA
LTYLELTALSYPAAAIALIGSGALRGAGTTKIPLLINGGMNILNILISSVLIYGIFSWPGLGFVGAGLGLTIARYIGAIA
TIWVLMVGLNPALRLSLKGYFKPFNFAIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVASLINL
PGNALGSASTIITGKRLGKGQIGQAEFQAWHVFWLSTIILTLIAWGSAPFAGFIASFYTHEEDVKEVVKQLLWLNALFMP
IWSLSWTLPCAFKGARDVRYTMWVSMLGMWGCRVVAGYTLGIVLGMGVIGVWLGMVLDWAVRGVLFYFRMVSGRWLWKYP
RVKASSEES
>Mature_489_residues
MLFQHFSLRSLLNVTSAVRQAVERTSWFKKRQRYRVLYWREISPLAVPILLENACVLLMGVLSTFLVSWLGKEAMAGVGL
ADSFNMVIMSFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLAIMTLFSILLAGVIHAFGQEIIDFVAGDATAQVKDLA
LTYLELTALSYPAAAIALIGSGALRGAGTTKIPLLINGGMNILNILISSVLIYGIFSWPGLGFVGAGLGLTIARYIGAIA
TIWVLMVGLNPALRLSLKGYFKPFNFAIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVASLINL
PGNALGSASTIITGKRLGKGQIGQAEFQAWHVFWLSTIILTLIAWGSAPFAGFIASFYTHEEDVKEVVKQLLWLNALFMP
IWSLSWTLPCAFKGARDVRYTMWVSMLGMWGCRVVAGYTLGIVLGMGVIGVWLGMVLDWAVRGVLFYFRMVSGRWLWKYP
RVKASSEES

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=489, Percent_Identity=77.3006134969325, Blast_Score=766, Evalue=0.0,
Organism=Escherichia coli, GI48994890, Length=458, Percent_Identity=24.4541484716157, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 53354; Mature: 53354

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFQHFSLRSLLNVTSAVRQAVERTSWFKKRQRYRVLYWREISPLAVPILLENACVLLMG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHH
VLSTFLVSWLGKEAMAGVGLADSFNMVIMSFFAAIDLGTTVVVAFSLGKRDRRRARAAAR
HHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHH
QSLAIMTLFSILLAGVIHAFGQEIIDFVAGDATAQVKDLALTYLELTALSYPAAAIALIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
SGALRGAGTTKIPLLINGGMNILNILISSVLIYGIFSWPGLGFVGAGLGLTIARYIGAIA
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TIWVLMVGLNPALRLSLKGYFKPFNFAIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGM
HHHHHHHCCCHHHEEEHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCC
GTNVIAGNFIAFSVASLINLPGNALGSASTIITGKRLGKGQIGQAEFQAWHVFWLSTIIL
CCCHHCCHHHHHHHHHHHCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
TLIAWGSAPFAGFIASFYTHEEDVKEVVKQLLWLNALFMPIWSLSWTLPCAFKGARDVRY
HHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
TMWVSMLGMWGCRVVAGYTLGIVLGMGVIGVWLGMVLDWAVRGVLFYFRMVSGRWLWKYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
RVKASSEES
CCCCCCCCC
>Mature Secondary Structure
MLFQHFSLRSLLNVTSAVRQAVERTSWFKKRQRYRVLYWREISPLAVPILLENACVLLMG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHH
VLSTFLVSWLGKEAMAGVGLADSFNMVIMSFFAAIDLGTTVVVAFSLGKRDRRRARAAAR
HHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHH
QSLAIMTLFSILLAGVIHAFGQEIIDFVAGDATAQVKDLALTYLELTALSYPAAAIALIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
SGALRGAGTTKIPLLINGGMNILNILISSVLIYGIFSWPGLGFVGAGLGLTIARYIGAIA
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
TIWVLMVGLNPALRLSLKGYFKPFNFAIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGM
HHHHHHHCCCHHHEEEHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCC
GTNVIAGNFIAFSVASLINLPGNALGSASTIITGKRLGKGQIGQAEFQAWHVFWLSTIIL
CCCHHCCHHHHHHHHHHHCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
TLIAWGSAPFAGFIASFYTHEEDVKEVVKQLLWLNALFMPIWSLSWTLPCAFKGARDVRY
HHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
TMWVSMLGMWGCRVVAGYTLGIVLGMGVIGVWLGMVLDWAVRGVLFYFRMVSGRWLWKYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
RVKASSEES
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]