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The map label for this gene is dhaR [H]

Identifier: 238895504

GI number: 238895504

Start: 3390903

End: 3391607

Strand: Reverse

Name: dhaR [H]

Synonym: KP1_3577

Alternate gene names: 238895504

Gene position: 3391607-3390903 (Counterclockwise)

Preceding gene: 238895506

Following gene: 238895503

Centisome position: 64.62

GC content: 60.71

Gene sequence:

>705_bases
ATGAATCCCGATACCTCCGCCGTCCTGAAGCCCCGCCGCGGCCGTCCACCCAAGGTCGATCGCCAGTTTGACGATACGCG
TCAGGCGCTGATTCGCTCAGGCCTTGAAGTGCTGACCGAAACGGGCTATCTCGCGGCGGGTATTGATGCGGTGATCAAGA
ATATCGCCGTGCCAAAGGGGTCGTTTTATCATTGCTTTAAAAGCAAAGAGGCCTTTGGCCTCGCCGTGCTTGCCGCCTAT
GGCGACTTCTTTGCGCATAAATTAGATAAATTCCTGCTGGACGACGCCGTGCCGCCGCTGGAACGGATGGCGGCCTTTGT
GCGTCATGCCGGTCAGGGAATGGAGAAATTCCAGTTTCGCCGCGGCTGCCTGGTGGGCAACCTGCTGCAGGAAGCCCCGT
TGTTACCCGAGACGTTTCCCCAACGGTTGATGGCTATCCTGGCGGCATGGGAGTCGCGCGTGGCGCGCTGCCTGCGCGAA
GCGCAGGCAGCCGGGGCCATCGCCAGCGACGCCTCACCGCAGGCGCTGGCCCAGGTGTTCTGGATCGGCTGGGAAGGCGC
GGTGATGCGCGCCAGGCTGGTCCAGTCTGCCGCACCGCTTAACCAGTACTGGGATTTTTTTGCGCACAGTATGACAACAA
AAACACCTGCACAGGACGGCGCTAGCGCCGATAACCCCCTTCCGACGAGGAATACTCTGTCATGA

Upstream 100 bases:

>100_bases
TCAGGATGATTGGTCAGCCAGCCTTACGCTACGCGCAATGCTTGCCCTACCCCTAAATTGGGCGTACCCTGACCAACAAT
TAAACCACACGGTCTAAATC

Downstream 100 bases:

>100_bases
AAGCATTAGTTCTGGACCAGATCGACAACCGCACCGTCGCCACCGTCAAAGATATCGACCTGCCCGCTCTTGCCGAAGGC
GACGTCCGGGTCGCCATCGA

Product: putative TetR-family trancriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNPDTSAVLKPRRGRPPKVDRQFDDTRQALIRSGLEVLTETGYLAAGIDAVIKNIAVPKGSFYHCFKSKEAFGLAVLAAY
GDFFAHKLDKFLLDDAVPPLERMAAFVRHAGQGMEKFQFRRGCLVGNLLQEAPLLPETFPQRLMAILAAWESRVARCLRE
AQAAGAIASDASPQALAQVFWIGWEGAVMRARLVQSAAPLNQYWDFFAHSMTTKTPAQDGASADNPLPTRNTLS

Sequences:

>Translated_234_residues
MNPDTSAVLKPRRGRPPKVDRQFDDTRQALIRSGLEVLTETGYLAAGIDAVIKNIAVPKGSFYHCFKSKEAFGLAVLAAY
GDFFAHKLDKFLLDDAVPPLERMAAFVRHAGQGMEKFQFRRGCLVGNLLQEAPLLPETFPQRLMAILAAWESRVARCLRE
AQAAGAIASDASPQALAQVFWIGWEGAVMRARLVQSAAPLNQYWDFFAHSMTTKTPAQDGASADNPLPTRNTLS
>Mature_234_residues
MNPDTSAVLKPRRGRPPKVDRQFDDTRQALIRSGLEVLTETGYLAAGIDAVIKNIAVPKGSFYHCFKSKEAFGLAVLAAY
GDFFAHKLDKFLLDDAVPPLERMAAFVRHAGQGMEKFQFRRGCLVGNLLQEAPLLPETFPQRLMAILAAWESRVARCLRE
AQAAGAIASDASPQALAQVFWIGWEGAVMRARLVQSAAPLNQYWDFFAHSMTTKTPAQDGASADNPLPTRNTLS

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=176, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25705; Mature: 25705

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPDTSAVLKPRRGRPPKVDRQFDDTRQALIRSGLEVLTETGYLAAGIDAVIKNIAVPKG
CCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
SFYHCFKSKEAFGLAVLAAYGDFFAHKLDKFLLDDAVPPLERMAAFVRHAGQGMEKFQFR
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
RGCLVGNLLQEAPLLPETFPQRLMAILAAWESRVARCLREAQAAGAIASDASPQALAQVF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHH
WIGWEGAVMRARLVQSAAPLNQYWDFFAHSMTTKTPAQDGASADNPLPTRNTLS
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNPDTSAVLKPRRGRPPKVDRQFDDTRQALIRSGLEVLTETGYLAAGIDAVIKNIAVPKG
CCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
SFYHCFKSKEAFGLAVLAAYGDFFAHKLDKFLLDDAVPPLERMAAFVRHAGQGMEKFQFR
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
RGCLVGNLLQEAPLLPETFPQRLMAILAAWESRVARCLREAQAAGAIASDASPQALAQVF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHH
WIGWEGAVMRARLVQSAAPLNQYWDFFAHSMTTKTPAQDGASADNPLPTRNTLS
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]