Click here to switch to the map view.

The map label for this gene is rcsA

Identifier: 238895481

GI number: 238895481

Start: 3367629

End: 3368252

Strand: Direct

Name: rcsA

Synonym: KP1_3552

Alternate gene names: 238895481

Gene position: 3367629-3368252 (Clockwise)

Preceding gene: 238895479

Following gene: 238895483

Centisome position: 64.16

GC content: 42.63

Gene sequence:

>624_bases
ATGTCAACGATGATTATGGATTTGTGCAGCTATACCCGGTTGGGATTGACGGGATATCTGACCAGTCGGGGAATTAAAAA
ACAGGAAATCGTTGAGGTCAACAGTGCTGCGGATCTGCAGAAACACTGTACGTCGTGTTGCCCGGCGGTGGTGTTTCTGA
ATGAAGACTGTTTCGTGCATGATGATGAAAGTAATGGCATTATTCGCCAGATCATTACGCAAAACCCGGCGACGCTGTTT
GTTATCTTTATGTCGCTGGCGAACATCCATTTTGACCGCTATTTGCGGGTACGGAAGAATCTGCTAATCAGTTCAAAATC
GATAACCCCAAAAGACCTTGATGTTATTCTGGTTAATTATCTTAAATACAAAAACACCAGTGTAGGGCAGTTAACTTTAC
CGACATTGTCACTGAGTAAAACAGAATCAAATATGCTGCAAATGTGGATGGCCGGGCATGGTACTTCGCAAATCTCAACG
CAAATGAACATCAAAGCGAAGACGGTATCGTCGCATAAAGGCAATATTAAAAAGAAAATACAAACGCATAATAAGCAGGT
GATTTATCATATCGTTCGGCTGACCGAAAACATCACCTCCGGTATTCAGGTAAATATGCGCTGA

Upstream 100 bases:

>100_bases
AATGGGTTCTTTCTAAACCTACTATTATTATCGCCCGCAAGGACTGCTTCGCACAGCCAGTGCGAAGTGTATATCGTTAC
GTGTTGATTGAGGATGGGTC

Downstream 100 bases:

>100_bases
AACAAACTGGCGGCGCTCCCGCCAGTTCAGTTTTACGAGACCTCTTTTTCCACAAAAATCCCATCCGGGTGGCCTATTTC
ATTAAAAAACCAGATCCCCA

Product: transcriptional activator for ctr capsule biosynthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSTMIMDLCSYTRLGLTGYLTSRGIKKQEIVEVNSAADLQKHCTSCCPAVVFLNEDCFVHDDESNGIIRQIITQNPATLF
VIFMSLANIHFDRYLRVRKNLLISSKSITPKDLDVILVNYLKYKNTSVGQLTLPTLSLSKTESNMLQMWMAGHGTSQIST
QMNIKAKTVSSHKGNIKKKIQTHNKQVIYHIVRLTENITSGIQVNMR

Sequences:

>Translated_207_residues
MSTMIMDLCSYTRLGLTGYLTSRGIKKQEIVEVNSAADLQKHCTSCCPAVVFLNEDCFVHDDESNGIIRQIITQNPATLF
VIFMSLANIHFDRYLRVRKNLLISSKSITPKDLDVILVNYLKYKNTSVGQLTLPTLSLSKTESNMLQMWMAGHGTSQIST
QMNIKAKTVSSHKGNIKKKIQTHNKQVIYHIVRLTENITSGIQVNMR
>Mature_206_residues
STMIMDLCSYTRLGLTGYLTSRGIKKQEIVEVNSAADLQKHCTSCCPAVVFLNEDCFVHDDESNGIIRQIITQNPATLFV
IFMSLANIHFDRYLRVRKNLLISSKSITPKDLDVILVNYLKYKNTSVGQLTLPTLSLSKTESNMLQMWMAGHGTSQISTQ
MNIKAKTVSSHKGNIKKKIQTHNKQVIYHIVRLTENITSGIQVNMR

Specific function: Positive regulator of capsular polysaccharide synthesis. RcsA and rcsB form a complex to promote transcription of the genes for capsule synthesis

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788262, Length=207, Percent_Identity=67.6328502415459, Blast_Score=291, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RCSA_KLEAE (P05338)

Other databases:

- EMBL:   M15748
- ProteinModelPortal:   P05338
- GO:   GO:0005622
- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421

Pfam domain/function: PF00196 GerE; SSF46894 Bipartite_resp_reg_C-effector

EC number: NA

Molecular weight: Translated: 23367; Mature: 23235

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMIMDLCSYTRLGLTGYLTSRGIKKQEIVEVNSAADLQKHCTSCCPAVVFLNEDCFVH
CCHHHHHHHHHHHCCHHHHHHHCCCCHHHHEECCCHHHHHHHHHHHCCEEEEECCCCEEE
DDESNGIIRQIITQNPATLFVIFMSLANIHFDRYLRVRKNLLISSKSITPKDLDVILVNY
ECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKYKNTSVGQLTLPTLSLSKTESNMLQMWMAGHGTSQISTQMNIKAKTVSSHKGNIKKKI
HHHCCCCCCEEEECEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHH
QTHNKQVIYHIVRLTENITSGIQVNMR
HHCCHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
STMIMDLCSYTRLGLTGYLTSRGIKKQEIVEVNSAADLQKHCTSCCPAVVFLNEDCFVH
CHHHHHHHHHHHCCHHHHHHHCCCCHHHHEECCCHHHHHHHHHHHCCEEEEECCCCEEE
DDESNGIIRQIITQNPATLFVIFMSLANIHFDRYLRVRKNLLISSKSITPKDLDVILVNY
ECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
LKYKNTSVGQLTLPTLSLSKTESNMLQMWMAGHGTSQISTQMNIKAKTVSSHKGNIKKKI
HHHCCCCCCEEEECEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHH
QTHNKQVIYHIVRLTENITSGIQVNMR
HHCCHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3309150