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The map label for this gene is znuA [H]

Identifier: 238895434

GI number: 238895434

Start: 3321505

End: 3322575

Strand: Reverse

Name: znuA [H]

Synonym: KP1_3502

Alternate gene names: 238895434

Gene position: 3322575-3321505 (Counterclockwise)

Preceding gene: 238895437

Following gene: 238895433

Centisome position: 63.3

GC content: 52.29

Gene sequence:

>1071_bases
TTGGCCAAAGGCCACCGAGACATTTTCCAGCGTTACAAGGTTTGTCATAGTAATTTAGGGGTTGCACAAGCTAGTGAATG
TTATAATATCACATCACACTCACTTATTTCGATGACTAGACGCATTATGTTACATAAAAATACGCTTCTTTGCGCTGGAC
TTGGCGCTGTTTTTTTGTTCGCGCAGGTACCGCTGGCCAGCGCCGCCGTGGTGACTTCTATGAAACCGCTGGGCTTTATT
GCGGCGGCCATCGCCGATGGGGTGACCGAGACCCAGGTGCTGCTGCCCGATGGCGCCTCCGAGCATGATTATTCCCTCCG
TCCTTCTGATGTAAAACGCTTACAGAACGCAGACTTAGTGGTGTGGATTGGTCCGGAAATGGAAGCCTTTATGGATAAGT
CGACGCAAAGCATTGCGGCGAATAAAAAGGTGACGATTGCCGAGCTGGATGGGGTCAAACCGCTGCTCATCACCGGGGCG
GACGACGATGACGATCACCATGGTCATGACCATGGCGCAGCAGAAAAAGGTGACGGCGATCACCATCACGGTATTTACAA
TATGCATCTGTGGTTATCCCCAGAGATAGCGCGGCTTTCGGCGGTTGCAATCCACGATAAATTATTGGAACTTATGCCGC
AGAGTCGAGCCAAACTCGACAGCAACCTGCAGCAGTTCGAGACCGCGCTGGCGGCGACCGACAAGCAGGTGAGCAATGAG
CTGGCACCGCTGAAAGGGAAGGGCTATTTCGTTTTTCATGACGCCTACGGTTACTTTGAAAAACACTACGGTTTGACCTC
GCTGGGGCACTTTACCGTCAACCCTGAAATACAGCCCGGTGCGCAGCGTTTACACGAAATCAGAACACAACTGGTTGAGC
AGAAAGCCACTTGCGTTTTTGCTGAGCCACAGTTCAGGCCAGCGGTTATCGAAGCTGTTGCCCGGGGCACGTCTGTGCGC
ATGGGGACCCTGGATCCACTGGGGACAGGAATTACGCTGGGTAAAACGAGTTACCCGCAATTCCTCACCCAACTGGCGAA
TCAGTATTCGAGCTGCCTGAAAGGAGATTAA

Upstream 100 bases:

>100_bases
CCACCCGCACAAGGGTCGATTTGCCGGCGCCGTTGGGGCCCAGCAGGGTTAAGATTTTGCCTGGCGTGAGAGCCAGCGAG
ATGTCAGACAACACGCGGCG

Downstream 100 bases:

>100_bases
CGAGGAAGTGAATACGTGCAACAGATAGCCCGCGCTGTCACTCAGGCATTCAACAATTTGCCACGACCTCATCGCGTCAT
GCTGGGGTCGCTTAGCGTTC

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MAKGHRDIFQRYKVCHSNLGVAQASECYNITSHSLISMTRRIMLHKNTLLCAGLGAVFLFAQVPLASAAVVTSMKPLGFI
AAAIADGVTETQVLLPDGASEHDYSLRPSDVKRLQNADLVVWIGPEMEAFMDKSTQSIAANKKVTIAELDGVKPLLITGA
DDDDDHHGHDHGAAEKGDGDHHHGIYNMHLWLSPEIARLSAVAIHDKLLELMPQSRAKLDSNLQQFETALAATDKQVSNE
LAPLKGKGYFVFHDAYGYFEKHYGLTSLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVIEAVARGTSVR
MGTLDPLGTGITLGKTSYPQFLTQLANQYSSCLKGD

Sequences:

>Translated_356_residues
MAKGHRDIFQRYKVCHSNLGVAQASECYNITSHSLISMTRRIMLHKNTLLCAGLGAVFLFAQVPLASAAVVTSMKPLGFI
AAAIADGVTETQVLLPDGASEHDYSLRPSDVKRLQNADLVVWIGPEMEAFMDKSTQSIAANKKVTIAELDGVKPLLITGA
DDDDDHHGHDHGAAEKGDGDHHHGIYNMHLWLSPEIARLSAVAIHDKLLELMPQSRAKLDSNLQQFETALAATDKQVSNE
LAPLKGKGYFVFHDAYGYFEKHYGLTSLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVIEAVARGTSVR
MGTLDPLGTGITLGKTSYPQFLTQLANQYSSCLKGD
>Mature_355_residues
AKGHRDIFQRYKVCHSNLGVAQASECYNITSHSLISMTRRIMLHKNTLLCAGLGAVFLFAQVPLASAAVVTSMKPLGFIA
AAIADGVTETQVLLPDGASEHDYSLRPSDVKRLQNADLVVWIGPEMEAFMDKSTQSIAANKKVTIAELDGVKPLLITGAD
DDDDHHGHDHGAAEKGDGDHHHGIYNMHLWLSPEIARLSAVAIHDKLLELMPQSRAKLDSNLQQFETALAATDKQVSNEL
APLKGKGYFVFHDAYGYFEKHYGLTSLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVIEAVARGTSVRM
GTLDPLGTGITLGKTSYPQFLTQLANQYSSCLKGD

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=316, Percent_Identity=75.6329113924051, Blast_Score=474, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 38883; Mature: 38751

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGHRDIFQRYKVCHSNLGVAQASECYNITSHSLISMTRRIMLHKNTLLCAGLGAVFLF
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AQVPLASAAVVTSMKPLGFIAAAIADGVTETQVLLPDGASEHDYSLRPSDVKRLQNADLV
HHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCEE
VWIGPEMEAFMDKSTQSIAANKKVTIAELDGVKPLLITGADDDDDHHGHDHGAAEKGDGD
EEECCCHHHHHCCHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
HHHGIYNMHLWLSPEIARLSAVAIHDKLLELMPQSRAKLDSNLQQFETALAATDKQVSNE
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAPLKGKGYFVFHDAYGYFEKHYGLTSLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVF
CCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEE
AEPQFRPAVIEAVARGTSVRMGTLDPLGTGITLGKTSYPQFLTQLANQYSSCLKGD
ECCCCCHHHHHHHHCCCCEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKGHRDIFQRYKVCHSNLGVAQASECYNITSHSLISMTRRIMLHKNTLLCAGLGAVFLF
CCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AQVPLASAAVVTSMKPLGFIAAAIADGVTETQVLLPDGASEHDYSLRPSDVKRLQNADLV
HHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHCCCCEE
VWIGPEMEAFMDKSTQSIAANKKVTIAELDGVKPLLITGADDDDDHHGHDHGAAEKGDGD
EEECCCHHHHHCCHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
HHHGIYNMHLWLSPEIARLSAVAIHDKLLELMPQSRAKLDSNLQQFETALAATDKQVSNE
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAPLKGKGYFVFHDAYGYFEKHYGLTSLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVF
CCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEE
AEPQFRPAVIEAVARGTSVRMGTLDPLGTGITLGKTSYPQFLTQLANQYSSCLKGD
ECCCCCHHHHHHHHCCCCEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 9600841; 9680209 [H]