Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 238895437

GI number: 238895437

Start: 3324129

End: 3325139

Strand: Reverse

Name: ruvB [H]

Synonym: KP1_3505

Alternate gene names: 238895437

Gene position: 3325139-3324129 (Counterclockwise)

Preceding gene: 238895438

Following gene: 238895434

Centisome position: 63.35

GC content: 61.23

Gene sequence:

>1011_bases
ATGATTGAAGCAGACCGGCTGGTATCGGCAGACAGCAGCGGCTTTGAAGAGGCCGCTGACCGCGCCATCCGCCCAAAATT
GCTGGCAGAGTATGTCGGCCAGCCGCAGGTGCGTTCGCAGATGGAGATCTTTATCCAGGCGGCGAAGCTGCGCGGCGACG
CCCTCGATCACCTGCTGATTTTTGGCCCGCCAGGGTTGGGGAAAACCACCCTGGCCAATATCGTCGCCAATGAAATGGGG
GTGAATCTGCGTACCACCTCCGGCCCGGTGCTGGAGAAGGCGGGCGACCTCGCCGCGATGCTCACCAACCTCGAACCGCA
CGATGTACTGTTTATCGATGAGATCCATCGCCTCTCGCCGGTGGTGGAAGAGGTGCTCTATCCGGCAATGGAAGACTACC
AGCTGGATATAATGATTGGCGAAGGTCCCGCGGCGCGTTCCATCAAGATCGATCTGCCGCCGTTTACCCTGATCGGCGCC
ACCACCCGCGCCGGTTCGTTGACCTCGCCGCTGCGCGACCGCTTTGGCATCGTGCAGCGTCTGGAGTTCTATCAGATCCC
CGATCTGCAGCATATTGTCAGCCGCAGCGCCCGCCATATGGGGCTGGAGATGAGCGACGAGGGCGCGCTGGAAGTAGCCC
GCCGTTCACGCGGCACGCCGCGTATTGCCAACCGTCTGCTGCGCCGGGTGCGTGACTTTGCGGAAGTGCGCCACGACGGC
ACCATCTCCGCCGATATTGCCGCCCAGGCGCTGGATATGCTTAACGTCGATGCGGAAGGGTTCGACTATATGGACCGTAA
GCTGCTGCTGGCGGTGATAGATAAGTTCTTTGGCGGCCCGGTGGGGCTGGATAACCTCGCCGCCGCGATTGGCGAAGAGC
GGGAAACCATTGAAGATGTACTGGAGCCCTACTTAATTCAGCAGGGCTTTCTGCAGCGTACGCCGCGGGGAAGAATGGCG
ACGGTGCGCGCCTGGAATCATTTCGGGATTACGCCGCCGGAAATGCCGTAG

Upstream 100 bases:

>100_bases
CGCAGGAGGCCAGCCGGATGGTCAGCAAGATCGCGCGTCCGGACGCCAACAGTGAAACGCTAATTCGCGAAGCGCTGCGC
GCTGCGTTGTGAGGTAAGGG

Downstream 100 bases:

>100_bases
CGCGTTGCGGTTGAGCAGTTCATGGTGAAGCCCGGTCAGCAGCGTGACCGGGCTTTTTCATTTTCAGCTGGCGGCTTTTT
TCGTCATGCTGAGAATAAAC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIEADRLVSADSSGFEEAADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
TTRAGSLTSPLRDRFGIVQRLEFYQIPDLQHIVSRSARHMGLEMSDEGALEVARRSRGTPRIANRLLRRVRDFAEVRHDG
TISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMA
TVRAWNHFGITPPEMP

Sequences:

>Translated_336_residues
MIEADRLVSADSSGFEEAADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
TTRAGSLTSPLRDRFGIVQRLEFYQIPDLQHIVSRSARHMGLEMSDEGALEVARRSRGTPRIANRLLRRVRDFAEVRHDG
TISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMA
TVRAWNHFGITPPEMP
>Mature_336_residues
MIEADRLVSADSSGFEEAADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
TTRAGSLTSPLRDRFGIVQRLEFYQIPDLQHIVSRSARHMGLEMSDEGALEVARRSRGTPRIANRLLRRVRDFAEVRHDG
TISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMA
TVRAWNHFGITPPEMP

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=336, Percent_Identity=94.9404761904762, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37146; Mature: 37146

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLVSADSSGFEEAADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKLRGDALDHLLI
CCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQR
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHH
LEFYQIPDLQHIVSRSARHMGLEMSDEGALEVARRSRGTPRIANRLLRRVRDFAEVRHDG
HHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
TISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDV
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MIEADRLVSADSSGFEEAADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKLRGDALDHLLI
CCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQR
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHH
LEFYQIPDLQHIVSRSARHMGLEMSDEGALEVARRSRGTPRIANRLLRRVRDFAEVRHDG
HHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
TISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDV
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA