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The map label for this gene is htpX [H]

Identifier: 238895405

GI number: 238895405

Start: 3291322

End: 3292206

Strand: Reverse

Name: htpX [H]

Synonym: KP1_3472

Alternate gene names: 238895405

Gene position: 3292206-3291322 (Counterclockwise)

Preceding gene: 238895406

Following gene: 238895403

Centisome position: 62.73

GC content: 56.84

Gene sequence:

>885_bases
ATGATGCGAATCGCGCTTTTCCTGCTGACGAACCTGGCAGTGATGGTCGTGTTCGGGCTGGTGTTAAGCCTCACGGGGAT
CCAATCCAGCAGCATGACCGGTCTTCTGATTATGGCCCTGCTGTTCGGCTTCGGTGGTTCTATCGTTTCGCTGATGATGT
CGAAGTGGATGGCGCTGAAGTCAGTGGGTGGGGAAGTGATCGAGCAGCCGCGCAACGAAACGGAACGCTGGCTGATGAAT
ACCGTTGCGCAGCAGGCGCAGCAGGTAGGTATTGCCATGCCGCAGGTAGCTATCTATCACGCGCCTGACATTAACGCCTT
CGCCACCGGCGCGCGTCGTGACGCCTCGCTGGTCGCCGTCAGCACCGGGCTGTTGCAAAACATGAGCCGTGATGAAGCGG
AAGCGGTCATTGCCCATGAAATCAGCCACATCGCCAATGGCGATATGGTTACCATGACCCTGATCCAGGGGGTGGTGAAC
ACCTTCGTTATCTTTATCTCCCGCGTTATCGCGCAGATTGCGGCCGGTTTCCTCGGCGGCAACCGGGAAGATGAAGGGGA
GAGCAGCAATGGCAACCCGCTGATCTACTTCGCCGTCGCCACGGTGCTTGAGCTGGTGTTCGGTATTCTGGCCAGCATAA
TCACCATGTGGTTCTCGCGTTACCGTGAGTTCCATGCTGACGCCGGCTCGGCGCGTCTGGTAGGCCGCGAGAAGATGATT
GCAGCCCTGCAGCGTCTGAAAACCAGCTATGAGCCGCAGGAAGCCAGCAGCATGATGGCGTTCTGCATTAACGGTAAAGC
GAAATCCATGAGCGAACTGTTTATGACTCACCCGCCGCTGGATAAGCGTATTGAAGCCCTGCGTAGCGGTGAATATCTGA
AATAA

Upstream 100 bases:

>100_bases
CGTGACTTAGCGGGGGCTGATGGTTGAAAATTGCAGCCTGACCCATACGATGTGGGTAATCGCATAGTGCGTTTTGTTAA
ATTGAGGTAAAAAGAAAATT

Downstream 100 bases:

>100_bases
TCTATCTTCTGACGCTGAAAACGAAAATCCGCAGCCCGCAAGCTGCGGATTTTTTTTACCGTCCGTCAGGCTGCGCGCGG
CTGAGTGACCCGCAGACCGC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSMTGLLIMALLFGFGGSIVSLMMSKWMALKSVGGEVIEQPRNETERWLMN
TVAQQAQQVGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHIANGDMVTMTLIQGVVN
TFVIFISRVIAQIAAGFLGGNREDEGESSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSARLVGREKMI
AALQRLKTSYEPQEASSMMAFCINGKAKSMSELFMTHPPLDKRIEALRSGEYLK

Sequences:

>Translated_294_residues
MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSMTGLLIMALLFGFGGSIVSLMMSKWMALKSVGGEVIEQPRNETERWLMN
TVAQQAQQVGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHIANGDMVTMTLIQGVVN
TFVIFISRVIAQIAAGFLGGNREDEGESSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSARLVGREKMI
AALQRLKTSYEPQEASSMMAFCINGKAKSMSELFMTHPPLDKRIEALRSGEYLK
>Mature_294_residues
MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSMTGLLIMALLFGFGGSIVSLMMSKWMALKSVGGEVIEQPRNETERWLMN
TVAQQAQQVGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHIANGDMVTMTLIQGVVN
TFVIFISRVIAQIAAGFLGGNREDEGESSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSARLVGREKMI
AALQRLKTSYEPQEASSMMAFCINGKAKSMSELFMTHPPLDKRIEALRSGEYLK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=294, Percent_Identity=91.4965986394558, Blast_Score=553, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 32047; Mature: 32047

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSMTGLLIMALLFGFGGSIVSLMMSKWMALK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVGGEVIEQPRNETERWLMNTVAQQAQQVGIAMPQVAIYHAPDINAFATGARRDASLVAV
HHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCCCHHHHHH
STGLLQNMSRDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRVIAQIAAGFLGG
HHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NREDEGESSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSARLVGREKMI
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AALQRLKTSYEPQEASSMMAFCINGKAKSMSELFMTHPPLDKRIEALRSGEYLK
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSMTGLLIMALLFGFGGSIVSLMMSKWMALK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVGGEVIEQPRNETERWLMNTVAQQAQQVGIAMPQVAIYHAPDINAFATGARRDASLVAV
HHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCCCHHHHHH
STGLLQNMSRDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRVIAQIAAGFLGG
HHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NREDEGESSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSARLVGREKMI
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AALQRLKTSYEPQEASSMMAFCINGKAKSMSELFMTHPPLDKRIEALRSGEYLK
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA