| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is prc [H]
Identifier: 238895406
GI number: 238895406
Start: 3292442
End: 3294538
Strand: Reverse
Name: prc [H]
Synonym: KP1_3473
Alternate gene names: 238895406
Gene position: 3294538-3292442 (Counterclockwise)
Preceding gene: 238895407
Following gene: 238895405
Centisome position: 62.77
GC content: 55.79
Gene sequence:
>2097_bases TTGTACGCGCAGAACACCTGGTGTTCTGAAACGGAGGCCGGGCCAGGCATGAACACATTTTTTAAAATCACCGCGCTTGC GGGCCTGCTGGCAATAGCAGGCCATGCATTCGCTGTTGATGACATAACCCGCGCAGATCAAATCCCCGTGCTGAAAGAAG AGCCGCAGCACGCGACGGTAAGCGAGCGCGTGACGTCGCGCTTTACCCGCTCTCATTACCGTCAGTTTGATCTCGACAAC GCCTTCTCGGCAAAGATTTTTGACCGTTACCTGAACCTGCTGGACTACAGCCACAATGTGCTGCTGGCCAGCGATGTGGC GAAGTTTGCGGCTAAAAAAGACCAAATTGGCGATGAGCTGCGCAGCGGGAAACTGGACGTCTTTTACGACCTCTACAACC TGGGGCAGCAGCGCCGCTTCGAGCGCTATCAGTATGCGCTGAAGGTGCTTGAACGTCCGATGGACTTTACCGGCAATGAT AATTTCAACCTTGACCGCTCCAAAGCGCCGTGGCCAAAAGACGAGGCCGAGCTGAACAAGCTGTGGGACGCTAAGGTTAA GTTTGACCAGTTAAGCCTGAAGCTGGCGGGTAAAGACGATAAAGAGATCCGCGACACCTTAACCCGTCGCTATAAGTTTG CTATCCGTCGCCTGGCGCAAACCAACAGCGAAGATGTCTTCTCGCTGGCGATGACCGCCTTCGCTCGCGAAATCGATCCG CACACAAATTATCTGTCGCCGCGTAATACCGAGCAGTTCAACACCGAAATGAGCCTCTCACTCGAGGGGATCGGCGCCGT GCTGCAGATGGATGATGACTATACCGTCATTAATTCGCTGGTGGCGGGCGGTCCAGCCGCGAAAAGCAAAGCGATCAGCG TCGGCGATCGCATCGTTGGCGTTGGCCAGACCGGGAAGTCGATGGTTGATGTCATCGGCTGGCGTCTGGATGACGTCGTG GCGCTGATTAAAGGGCCGAAGGGCAGCAAGGTTCGTCTTGAAATCCTGCCGGCCGGTAAAGGAGCCAAGACGCGTATTGT AACGCTGACCCGCGAGCGCATTCGTCTGGAAGACCGTGCGGTGAAGATGTCGGTGAAAACCGTCGGGAAAGAAAAAGTCG GCGTGCTGGATATTCCAGGCTTTTACGTTGGCCTGACCGATGACGTGAAAGTGCAGCTGCAGAAGCTGGAAAAACAGAAC GTCAGCAGCATCATCATTGACCTGCGCAGCAACGGCGGCGGAGCGCTGACAGAGGCGGTATCGCTCTCGGGTCTGTTTAT TCCGTCCGGTCCGGTGGTGCAGGTGCGGGATAATAATGGCAAAGTGCGCGAAGACAGCGACAACGATGGCGTGGTTTATT ACAAAGGGCCGCTGGTGGTGCTGGTTGACCGCTTTAGCGCCTCGGCGTCTGAGATCTTCGCCGCAGCGATGCAGGACTAT GGCCGCGCGCTGATCGTTGGCGAACCGACCTTCGGTAAAGGGACGGTACAGCAGTATCGCTCGTTGAATCGTATTTACGA TCAAATGCTGCGTCCGGAGTGGCCGGCGTTGGGTTCCGTCCAGTACACCATCCAGAAGTTCTATCGTATTAACGGCGGCA GTACGCAGCGCAAAGGCGTGACGCCGGATATCATGATGCCAACCGGCAATGAAGATCGCGAAACCGGCGAGCAGTATGAA GACAACGCGCTGCCGTGGGATAGCATCAACGCGGCCACCTATGTGAAGTCCGGGGATCTGACCCCGTTTGGACCGGAGCT GCTCAAGCGCCACGACGAGCGTATTGCGCAGGATCCTGAATTCCAGTACATCATGAAGGATATTGCCCGTTATAACGCGA TGAAGGACAAACGTAACATCGTCTCTCTGAACTACGCCCAGCGTGAGAAAGAGAACGAAGAAGATGATGCGATTCGTCTG GCGCGGATTAACGATCGCCTGAAACGCGAAGGCAAGCCGCCGTTGAAAAAACTGGACGATCTGCCGAAGGATTACCAGGA GCCGGATCCATATCTTGATGAAACGGTCCATATCGCGGTAGACCTGGCGCATCTGGAAAAAGCGCGCCCGGCGGTGGAAC CGCCGGCCAGCAAATAA
Upstream 100 bases:
>100_bases GCGCTGAAGGTAAAAGCAGGCAATAACGCCATGGACGCCACCGTTCTGGAAATCACCAAAGATGGCGTTCGTGTACAGCT GACTTCTGGTATGTCAATGA
Downstream 100 bases:
>100_bases GTTGCTAACGGGCACCCTGAGAGGTGCCCGTTTTTTTTGTGCGCGTTGTCATCGCCATTCAGCTCATCTAACAAAATGTC AACCTGCGCTGCCGCTGTCA
Product: carboxy-terminal protease
Products: NA
Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]
Number of amino acids: Translated: 698; Mature: 698
Protein sequence:
>698_residues MYAQNTWCSETEAGPGMNTFFKITALAGLLAIAGHAFAVDDITRADQIPVLKEEPQHATVSERVTSRFTRSHYRQFDLDN AFSAKIFDRYLNLLDYSHNVLLASDVAKFAAKKDQIGDELRSGKLDVFYDLYNLGQQRRFERYQYALKVLERPMDFTGND NFNLDRSKAPWPKDEAELNKLWDAKVKFDQLSLKLAGKDDKEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDP HTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKAISVGDRIVGVGQTGKSMVDVIGWRLDDVV ALIKGPKGSKVRLEILPAGKGAKTRIVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQN VSSIIIDLRSNGGGALTEAVSLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDY GRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRINGGSTQRKGVTPDIMMPTGNEDRETGEQYE DNALPWDSINAATYVKSGDLTPFGPELLKRHDERIAQDPEFQYIMKDIARYNAMKDKRNIVSLNYAQREKENEEDDAIRL ARINDRLKREGKPPLKKLDDLPKDYQEPDPYLDETVHIAVDLAHLEKARPAVEPPASK
Sequences:
>Translated_698_residues MYAQNTWCSETEAGPGMNTFFKITALAGLLAIAGHAFAVDDITRADQIPVLKEEPQHATVSERVTSRFTRSHYRQFDLDN AFSAKIFDRYLNLLDYSHNVLLASDVAKFAAKKDQIGDELRSGKLDVFYDLYNLGQQRRFERYQYALKVLERPMDFTGND NFNLDRSKAPWPKDEAELNKLWDAKVKFDQLSLKLAGKDDKEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDP HTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKAISVGDRIVGVGQTGKSMVDVIGWRLDDVV ALIKGPKGSKVRLEILPAGKGAKTRIVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQN VSSIIIDLRSNGGGALTEAVSLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDY GRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRINGGSTQRKGVTPDIMMPTGNEDRETGEQYE DNALPWDSINAATYVKSGDLTPFGPELLKRHDERIAQDPEFQYIMKDIARYNAMKDKRNIVSLNYAQREKENEEDDAIRL ARINDRLKREGKPPLKKLDDLPKDYQEPDPYLDETVHIAVDLAHLEKARPAVEPPASK >Mature_698_residues MYAQNTWCSETEAGPGMNTFFKITALAGLLAIAGHAFAVDDITRADQIPVLKEEPQHATVSERVTSRFTRSHYRQFDLDN AFSAKIFDRYLNLLDYSHNVLLASDVAKFAAKKDQIGDELRSGKLDVFYDLYNLGQQRRFERYQYALKVLERPMDFTGND NFNLDRSKAPWPKDEAELNKLWDAKVKFDQLSLKLAGKDDKEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDP HTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKAISVGDRIVGVGQTGKSMVDVIGWRLDDVV ALIKGPKGSKVRLEILPAGKGAKTRIVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQN VSSIIIDLRSNGGGALTEAVSLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDY GRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRINGGSTQRKGVTPDIMMPTGNEDRETGEQYE DNALPWDSINAATYVKSGDLTPFGPELLKRHDERIAQDPEFQYIMKDIARYNAMKDKRNIVSLNYAQREKENEEDDAIRL ARINDRLKREGKPPLKKLDDLPKDYQEPDPYLDETVHIAVDLAHLEKARPAVEPPASK
Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]
COG id: COG0793
COG function: function code M; Periplasmic protease
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PDZ (DHR) domain [H]
Homologues:
Organism=Escherichia coli, GI1788134, Length=682, Percent_Identity=89.8826979472141, Blast_Score=1268, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001478 - InterPro: IPR005151 - InterPro: IPR004447 - InterPro: IPR020992 [H]
Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]
EC number: =3.4.21.102 [H]
Molecular weight: Translated: 78399; Mature: 78399
Theoretical pI: Translated: 6.55; Mature: 6.55
Prosite motif: PS50106 PDZ
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYAQNTWCSETEAGPGMNTFFKITALAGLLAIAGHAFAVDDITRADQIPVLKEEPQHATV CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCCCCCCCCCCCHH SERVTSRFTRSHYRQFDLDNAFSAKIFDRYLNLLDYSHNVLLASDVAKFAAKKDQIGDEL HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH RSGKLDVFYDLYNLGQQRRFERYQYALKVLERPMDFTGNDNFNLDRSKAPWPKDEAELNK HCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH LWDAKVKFDQLSLKLAGKDDKEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDP HHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC HTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKAISVGDRIVG CCCCCCCCCCHHCCCEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCEEECCCEEEE VGQTGKSMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGAKTRIVTLTRERIRLEDRA CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHHHH VKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSIIIDLRSNGGGALTEAV HEEHHHHCCCCCCCEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH SLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDY HHCEEEECCCCEEEEECCCCCEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHH GRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRINGGSTQRKGV CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCCCCC TPDIMMPTGNEDRETGEQYEDNALPWDSINAATYVKSGDLTPFGPELLKRHDERIAQDPE CCCEECCCCCCCHHCCHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCC FQYIMKDIARYNAMKDKRNIVSLNYAQREKENEEDDAIRLARINDRLKREGKPPLKKLDD HHHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCCHHHEEHHHHHHHHHHCCCCCHHHHHC LPKDYQEPDPYLDETVHIAVDLAHLEKARPAVEPPASK CCHHHCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCC >Mature Secondary Structure MYAQNTWCSETEAGPGMNTFFKITALAGLLAIAGHAFAVDDITRADQIPVLKEEPQHATV CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCCCCCCCCCCCHH SERVTSRFTRSHYRQFDLDNAFSAKIFDRYLNLLDYSHNVLLASDVAKFAAKKDQIGDEL HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH RSGKLDVFYDLYNLGQQRRFERYQYALKVLERPMDFTGNDNFNLDRSKAPWPKDEAELNK HCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH LWDAKVKFDQLSLKLAGKDDKEIRDTLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDP HHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC HTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKAISVGDRIVG CCCCCCCCCCHHCCCEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCCCCEEECCCEEEE VGQTGKSMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGAKTRIVTLTRERIRLEDRA CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHHHH VKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSIIIDLRSNGGGALTEAV HEEHHHHCCCCCCCEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH SLSGLFIPSGPVVQVRDNNGKVREDSDNDGVVYYKGPLVVLVDRFSASASEIFAAAMQDY HHCEEEECCCCEEEEECCCCCEECCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHH GRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRINGGSTQRKGV CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCCCCC TPDIMMPTGNEDRETGEQYEDNALPWDSINAATYVKSGDLTPFGPELLKRHDERIAQDPE CCCEECCCCCCCHHCCHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCC FQYIMKDIARYNAMKDKRNIVSLNYAQREKENEEDDAIRLARINDRLKREGKPPLKKLDD HHHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCCHHHEEHHHHHHHHHHCCCCCHHHHHC LPKDYQEPDPYLDETVHIAVDLAHLEKARPAVEPPASK CCHHHCCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]