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The map label for this gene is dgoT [H]

Identifier: 238895178

GI number: 238895178

Start: 3059244

End: 3060566

Strand: Reverse

Name: dgoT [H]

Synonym: KP1_3224

Alternate gene names: 238895178

Gene position: 3060566-3059244 (Counterclockwise)

Preceding gene: 238895179

Following gene: 238895177

Centisome position: 58.31

GC content: 63.11

Gene sequence:

>1323_bases
ATGAGCTCATATAGCCCTAACCCGACGGCTGCCGCCCAGCCAGCCGTCACCGTGCGCCGCTCCCGGCGGCGTATCGGCAT
TCTTGCGCTGTTGGCCATTGGCACCATGATCAACTATCTCGATCGCACCGTACTGGGGATCGCCGCCCCAAAGCTCACCG
CTGAGCTGGGGATCGACCCGGCGATCATGGGAATCCTCTTCTCCGCCTTCGCCTGGACCTATGCTCTGGCGCAGATCCCC
GGCGGATTGTTTCTCGACCGCTTTGGCAACAAAGTGACCTACTTTTTGTCACTGACCCTGTGGTCGCTGTTTACCCTGTT
CCACGGCATGGCGGTGGGGCTGAAGACGCTGCTGCTGTGCCGCTTCGGGCTCGGCATTAGCGAAGCGCCGTGCTTTCCGG
TCAACAGCCGGGTGGTCAGCGCCTGGTTCCCACAGCAGGAGCGGGCGAAGGCCACGGCGGTGTACACCGTGGGGGAGTAT
CTCGGGCTGGCCTGCTTTGCGCCGCTGCTGTTCTGGATCATGGACGGTTTCGGCTGGCGGGTGCTGTTCGTCAGCGTTGG
CGCCGTCGGCATTCTGTTTGCCCTGGTGTGGTGGCGCTGCTACCGCGAACCGCATGAAGATCCGCGCCTTAGCCAGCAGG
AGCGCGAGCATATCGAAAACGGCGGCGGCCTCAGCGCCCCGACCGACCAGCAGGTGGCGTTCAGCTGGCCGCTGGTCCGC
CAGCTGCTGAGCAAACGGCAGATCATCGGCGCCAGCATCGGCCAGTTTGCCGGCAATACCGTGCTGGTGTTTTTTCTCAC
CTGGTTCCCCACCTGGCTGGCCACCGAGCGGCATATGCCCTGGCTGAAGGTTGGCTTCTTCTCCATCCTGCCGTTTGTCG
CCGCCGCCGGCGGGGTGATGTTTGGCGGCTGGCTCTCCGACAAACTGCTCAAGGCCACCGGGTCGGCCAACCTCGGTCGT
AAGCTGCCGATCGTCGCCGGTCTGCTGATGGCCAGCTGCATCATTACCGCCAACTGGCTGGAGAGCGACCTGGCGGTGAT
CCTGGTGATGTCGTTTGCCTTTTTTGGCCAGGGGATGGTGGGTCTCGGCTGGACGCTGATCTCCGATATCGCCCCGAAGG
GGCTGGGCGGTCTGACCGGCGGCCTGTTTAACTTCTGCGCCAACCTCGCGGGGATCCTCACCCCGCTGGTGATCGGCTTT
ATCGTTGCCGGGTTCGGCAATTTCTTCTACGCCTTGATCTACATCGGCGGCGCCGCGCTGCTGGGCGTGGTGGCCTATCT
GTTTATCCTCGGCGACGTCAAACGTATCGAGTTATCGCAGTAA

Upstream 100 bases:

>100_bases
TCCGTCTGGCGGCGATGCAGTATTGTTAGCCTGAATCAAATGGTTCATTATGCGTTAAACACAATAACAACACCCTCTGT
ACCCGAGACAGGAACCGACT

Downstream 100 bases:

>100_bases
GCAAAGGAGCAAGGCATGGTGATTAGTGGGCATACGCGGCTGATAGCGCACCTTGGCTATCCGACCGCCAGTTTTAAGGC
GCCGATGATCTACAACCCGT

Product: putative permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSSYSPNPTAAAQPAVTVRRSRRRIGILALLAIGTMINYLDRTVLGIAAPKLTAELGIDPAIMGILFSAFAWTYALAQIP
GGLFLDRFGNKVTYFLSLTLWSLFTLFHGMAVGLKTLLLCRFGLGISEAPCFPVNSRVVSAWFPQQERAKATAVYTVGEY
LGLACFAPLLFWIMDGFGWRVLFVSVGAVGILFALVWWRCYREPHEDPRLSQQEREHIENGGGLSAPTDQQVAFSWPLVR
QLLSKRQIIGASIGQFAGNTVLVFFLTWFPTWLATERHMPWLKVGFFSILPFVAAAGGVMFGGWLSDKLLKATGSANLGR
KLPIVAGLLMASCIITANWLESDLAVILVMSFAFFGQGMVGLGWTLISDIAPKGLGGLTGGLFNFCANLAGILTPLVIGF
IVAGFGNFFYALIYIGGAALLGVVAYLFILGDVKRIELSQ

Sequences:

>Translated_440_residues
MSSYSPNPTAAAQPAVTVRRSRRRIGILALLAIGTMINYLDRTVLGIAAPKLTAELGIDPAIMGILFSAFAWTYALAQIP
GGLFLDRFGNKVTYFLSLTLWSLFTLFHGMAVGLKTLLLCRFGLGISEAPCFPVNSRVVSAWFPQQERAKATAVYTVGEY
LGLACFAPLLFWIMDGFGWRVLFVSVGAVGILFALVWWRCYREPHEDPRLSQQEREHIENGGGLSAPTDQQVAFSWPLVR
QLLSKRQIIGASIGQFAGNTVLVFFLTWFPTWLATERHMPWLKVGFFSILPFVAAAGGVMFGGWLSDKLLKATGSANLGR
KLPIVAGLLMASCIITANWLESDLAVILVMSFAFFGQGMVGLGWTLISDIAPKGLGGLTGGLFNFCANLAGILTPLVIGF
IVAGFGNFFYALIYIGGAALLGVVAYLFILGDVKRIELSQ
>Mature_439_residues
SSYSPNPTAAAQPAVTVRRSRRRIGILALLAIGTMINYLDRTVLGIAAPKLTAELGIDPAIMGILFSAFAWTYALAQIPG
GLFLDRFGNKVTYFLSLTLWSLFTLFHGMAVGLKTLLLCRFGLGISEAPCFPVNSRVVSAWFPQQERAKATAVYTVGEYL
GLACFAPLLFWIMDGFGWRVLFVSVGAVGILFALVWWRCYREPHEDPRLSQQEREHIENGGGLSAPTDQQVAFSWPLVRQ
LLSKRQIIGASIGQFAGNTVLVFFLTWFPTWLATERHMPWLKVGFFSILPFVAAAGGVMFGGWLSDKLLKATGSANLGRK
LPIVAGLLMASCIITANWLESDLAVILVMSFAFFGQGMVGLGWTLISDIAPKGLGGLTGGLFNFCANLAGILTPLVIGFI
VAGFGNFFYALIYIGGAALLGVVAYLFILGDVKRIELSQ

Specific function: Intake of galactonate into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI148743791, Length=394, Percent_Identity=27.6649746192893, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI9945322, Length=434, Percent_Identity=25.1152073732719, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI21322234, Length=410, Percent_Identity=24.8780487804878, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI154350196, Length=414, Percent_Identity=24.3961352657005, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI9966811, Length=359, Percent_Identity=23.6768802228412, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI148728191, Length=333, Percent_Identity=27.6276276276276, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI6912666, Length=347, Percent_Identity=25.6484149855908, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI5031955, Length=269, Percent_Identity=28.2527881040892, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4885441, Length=391, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI223718438, Length=410, Percent_Identity=24.1463414634146, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI154800443, Length=349, Percent_Identity=24.0687679083095, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082320, Length=437, Percent_Identity=43.4782608695652, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1789152, Length=447, Percent_Identity=42.2818791946309, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1789515, Length=440, Percent_Identity=42.0454545454545, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI2367379, Length=437, Percent_Identity=30.2059496567506, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI2367193, Length=435, Percent_Identity=27.5862068965517, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1788573, Length=454, Percent_Identity=23.3480176211454, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533556, Length=427, Percent_Identity=26.463700234192, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI115533554, Length=421, Percent_Identity=26.603325415677, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560030, Length=378, Percent_Identity=26.1904761904762, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17552542, Length=385, Percent_Identity=24.9350649350649, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17535049, Length=439, Percent_Identity=21.6400911161731, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193205400, Length=233, Percent_Identity=21.4592274678112, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=365, Percent_Identity=23.8356164383562, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=365, Percent_Identity=23.8356164383562, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=365, Percent_Identity=23.8356164383562, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=405, Percent_Identity=21.4814814814815, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=301, Percent_Identity=24.2524916943522, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=353, Percent_Identity=18.9801699716714, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28573299, Length=394, Percent_Identity=26.6497461928934, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583789, Length=349, Percent_Identity=24.0687679083095, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45550460, Length=440, Percent_Identity=26.8181818181818, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24655255, Length=396, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24641682, Length=391, Percent_Identity=24.8081841432225, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648416, Length=462, Percent_Identity=23.1601731601732, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356189, Length=462, Percent_Identity=23.1601731601732, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI62484226, Length=390, Percent_Identity=24.8717948717949, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24639764, Length=398, Percent_Identity=24.8743718592965, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129235, Length=356, Percent_Identity=28.0898876404494, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584153, Length=387, Percent_Identity=21.1886304909561, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24653727, Length=398, Percent_Identity=24.1206030150754, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19922400, Length=368, Percent_Identity=24.1847826086957, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654215, Length=361, Percent_Identity=23.8227146814404, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655271, Length=406, Percent_Identity=23.8916256157635, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130135, Length=406, Percent_Identity=23.8916256157635, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580790, Length=353, Percent_Identity=24.3626062322946, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24658658, Length=401, Percent_Identity=23.1920199501247, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573708, Length=351, Percent_Identity=23.9316239316239, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573707, Length=351, Percent_Identity=23.9316239316239, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920686, Length=402, Percent_Identity=24.3781094527363, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221474708, Length=157, Percent_Identity=30.5732484076433, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47772; Mature: 47641

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure 
SSYSPNPTAAAQPAVTVRRSRRRIGILALLAIGTMINYLDRTVLGIAAPKLTAELGIDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCH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HHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]