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The map label for this gene is aroE [H]

Identifier: 238895177

GI number: 238895177

Start: 3058392

End: 3059228

Strand: Reverse

Name: aroE [H]

Synonym: KP1_3223

Alternate gene names: 238895177

Gene position: 3059228-3058392 (Counterclockwise)

Preceding gene: 238895178

Following gene: 238895176

Centisome position: 58.29

GC content: 64.52

Gene sequence:

>837_bases
ATGGTGATTAGTGGGCATACGCGGCTGATAGCGCACCTTGGCTATCCGACCGCCAGTTTTAAGGCGCCGATGATCTACAA
CCCGTGGTTCGTTGACCAGCAGGTGGACGTGAAGGTGGTGCCGATGGGGGTCAGGCCGGAGGACTACGCCGCGTTTATTC
CGCCGCTGTTTACGATGACCAACATCATCGGCGCGCTGGTGACGATGCCGCATAAAATCGCTACCTGCGATCTGGTGCAG
CGCCTGAGCCCGACGGCGGCCATCGCTGGCGCCTGCAATGCCATCCGCCGCGAGGCTGACGGTAGCCTGAGCGGAGACAT
GTTCGATGGCGAGGGATTTGTGCTGGGCCTGCGTCGTAAAGGGTTTAACCCGCAGGGGACGCGGGCGCTGGTGGTTGGCA
GCGGCGGGGTGGGATCGGCTATCGCCGCCTCCCTCGCGGCGGCGGGGGTCAGCGCCCTGACCCTGTACGATACCCGGCCC
GAGGTGGCGCACGCCCTCGCCGGGCGGCTGCATCAGCACTATCCGCAGCTCGATATCACCCTGATGCAGCCCGATCCTGC
CGGACACGAGCTGGTGGTCAATGCCACCCCGCTGGGGATGAAGGCCAGCGATCCGCTGCCGCTGGACGTTGACCGTCTGG
CGCCAGGCGCCTGGGTGGGGGAAGTCGTCATGACTCAGGAGTACACCCCGCTGCTGAGGGCCGCTCAGGCACGACAGTGC
CACATCCAGCGCGGGACCGACATGCTGTTTGAAATGATCCCTGCCTATCTGCGCTTTTTTGACCTACCGGTAGCCACCCC
CGAGCAGCTGCGGACCCTGGCAGAAATTCGCTACTGA

Upstream 100 bases:

>100_bases
CTACATCGGCGGCGCCGCGCTGCTGGGCGTGGTGGCCTATCTGTTTATCCTCGGCGACGTCAAACGTATCGAGTTATCGC
AGTAAGCAAAGGAGCAAGGC

Downstream 100 bases:

>100_bases
CGCGACGGCAAACCGGGTAATATAGCGTTATATTATCCGGTTTATAGCGATATCCTATGGCAAACACCACTCTCACGCTG
CTGGCGGCGGGAAGCCTGAG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MVISGHTRLIAHLGYPTASFKAPMIYNPWFVDQQVDVKVVPMGVRPEDYAAFIPPLFTMTNIIGALVTMPHKIATCDLVQ
RLSPTAAIAGACNAIRREADGSLSGDMFDGEGFVLGLRRKGFNPQGTRALVVGSGGVGSAIAASLAAAGVSALTLYDTRP
EVAHALAGRLHQHYPQLDITLMQPDPAGHELVVNATPLGMKASDPLPLDVDRLAPGAWVGEVVMTQEYTPLLRAAQARQC
HIQRGTDMLFEMIPAYLRFFDLPVATPEQLRTLAEIRY

Sequences:

>Translated_278_residues
MVISGHTRLIAHLGYPTASFKAPMIYNPWFVDQQVDVKVVPMGVRPEDYAAFIPPLFTMTNIIGALVTMPHKIATCDLVQ
RLSPTAAIAGACNAIRREADGSLSGDMFDGEGFVLGLRRKGFNPQGTRALVVGSGGVGSAIAASLAAAGVSALTLYDTRP
EVAHALAGRLHQHYPQLDITLMQPDPAGHELVVNATPLGMKASDPLPLDVDRLAPGAWVGEVVMTQEYTPLLRAAQARQC
HIQRGTDMLFEMIPAYLRFFDLPVATPEQLRTLAEIRY
>Mature_278_residues
MVISGHTRLIAHLGYPTASFKAPMIYNPWFVDQQVDVKVVPMGVRPEDYAAFIPPLFTMTNIIGALVTMPHKIATCDLVQ
RLSPTAAIAGACNAIRREADGSLSGDMFDGEGFVLGLRRKGFNPQGTRALVVGSGGVGSAIAASLAAAGVSALTLYDTRP
EVAHALAGRLHQHYPQLDITLMQPDPAGHELVVNATPLGMKASDPLPLDVDRLAPGAWVGEVVMTQEYTPLLRAAQARQC
HIQRGTDMLFEMIPAYLRFFDLPVATPEQLRTLAEIRY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=262, Percent_Identity=27.8625954198473, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789675, Length=232, Percent_Identity=30.1724137931034, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30012; Mature: 30012

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISGHTRLIAHLGYPTASFKAPMIYNPWFVDQQVDVKVVPMGVRPEDYAAFIPPLFTMT
CEECCCCEEEEECCCCCCCCCCCEEECCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHH
NIIGALVTMPHKIATCDLVQRLSPTAAIAGACNAIRREADGSLSGDMFDGEGFVLGLRRK
HHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEEEECC
GFNPQGTRALVVGSGGVGSAIAASLAAAGVSALTLYDTRPEVAHALAGRLHQHYPQLDIT
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEE
LMQPDPAGHELVVNATPLGMKASDPLPLDVDRLAPGAWVGEVVMTQEYTPLLRAAQARQC
EECCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHHEEECCCCCHHHHHHHHHHH
HIQRGTDMLFEMIPAYLRFFDLPVATPEQLRTLAEIRY
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVISGHTRLIAHLGYPTASFKAPMIYNPWFVDQQVDVKVVPMGVRPEDYAAFIPPLFTMT
CEECCCCEEEEECCCCCCCCCCCEEECCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHH
NIIGALVTMPHKIATCDLVQRLSPTAAIAGACNAIRREADGSLSGDMFDGEGFVLGLRRK
HHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEEEECC
GFNPQGTRALVVGSGGVGSAIAASLAAAGVSALTLYDTRPEVAHALAGRLHQHYPQLDIT
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEE
LMQPDPAGHELVVNATPLGMKASDPLPLDVDRLAPGAWVGEVVMTQEYTPLLRAAQARQC
EECCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHHEEECCCCCHHHHHHHHHHH
HIQRGTDMLFEMIPAYLRFFDLPVATPEQLRTLAEIRY
HHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA