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The map label for this gene is ccmB [H]

Identifier: 238895116

GI number: 238895116

Start: 2992996

End: 2993655

Strand: Reverse

Name: ccmB [H]

Synonym: KP1_3155

Alternate gene names: 238895116

Gene position: 2993655-2992996 (Counterclockwise)

Preceding gene: 238895117

Following gene: 238895115

Centisome position: 57.04

GC content: 68.94

Gene sequence:

>660_bases
ATGATGCGTGCGCTGTTGGCCCGGGAACTGCGCCTGGCGTGGCGCAGCGGGGCGGAGATCCTCAATCCGCTCTGGTTCTT
TCTGATCGTCATCACCCTGTTTCCGTTCGGCGTAGGCGCCGCGCCGCAGCTGCTGGCGCAGATTGCGCCGGGCGTGGTGT
GGGTCGCCGCGCTGCTGGCGGCGCTGCTGGTGATGGATCGGTTGTTTCGCGACGACTGGCAGGACGGTTCCCTGGAGCAA
CTGATGCTCCTGCCGACGCCGCTGGTGGCGGTGGTGCTGGTGAAGGTGGTTGCCCACTGGATGATGAGCGGCCTGCCGCT
GCTGATCGTCTCGCCGCTGGCGGCGCTGCTGCTGGGGATGAGTCTGCATGACGCCGGTGTGCTGGCGATGACCTTGCTGC
TTGGCACCCCGACGCTCAGTTTTCTCGGCGCGGTGGGGGTTGGCCTGACGGTCGGCCTGAAGCGCGGCGGCGTCCTGCTG
AGCCTGCTGGTGCTGCCGCTGGCGGTGCCGCTGCTGATTTTCGCCACCGCGGCCTGCCAGGCGGCCGCCGCCGAGCTCCC
GGTTGGCGGCTATCTGGCGATGCTGGCGGCGTTCTTAACCGCCAGCGCCACCCTGTGTCCGTTCGCCACCGCCGCTGCGC
TGCGGCTGACCGTGCGATAA

Upstream 100 bases:

>100_bases
GGCAGGGGGGATGCGCCATCCTCACCACCCACCAGCCGCTGCGGCCGCTGGGCTGTCCGTTGCGCACCCTGCGCCTCGGC
GGCGACGCTGGAGGCGGGCA

Downstream 100 bases:

>100_bases
CTCGCTGCGCCTGCGGGCGCGGCCATCATAACCGTGTGAGTAAGCGTCTATGTGGAAAGCGTTACATCAACTGGCGATCC
CCGAGCGGCTGTACCGCCTG

Product: heme exporter permease component

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MMRALLARELRLAWRSGAEILNPLWFFLIVITLFPFGVGAAPQLLAQIAPGVVWVAALLAALLVMDRLFRDDWQDGSLEQ
LMLLPTPLVAVVLVKVVAHWMMSGLPLLIVSPLAALLLGMSLHDAGVLAMTLLLGTPTLSFLGAVGVGLTVGLKRGGVLL
SLLVLPLAVPLLIFATAACQAAAAELPVGGYLAMLAAFLTASATLCPFATAAALRLTVR

Sequences:

>Translated_219_residues
MMRALLARELRLAWRSGAEILNPLWFFLIVITLFPFGVGAAPQLLAQIAPGVVWVAALLAALLVMDRLFRDDWQDGSLEQ
LMLLPTPLVAVVLVKVVAHWMMSGLPLLIVSPLAALLLGMSLHDAGVLAMTLLLGTPTLSFLGAVGVGLTVGLKRGGVLL
SLLVLPLAVPLLIFATAACQAAAAELPVGGYLAMLAAFLTASATLCPFATAAALRLTVR
>Mature_219_residues
MMRALLARELRLAWRSGAEILNPLWFFLIVITLFPFGVGAAPQLLAQIAPGVVWVAALLAALLVMDRLFRDDWQDGSLEQ
LMLLPTPLVAVVLVKVVAHWMMSGLPLLIVSPLAALLLGMSLHDAGVLAMTLLLGTPTLSFLGAVGVGLTVGLKRGGVLL
SLLVLPLAVPLLIFATAACQAAAAELPVGGYLAMLAAFLTASATLCPFATAAALRLTVR

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=211, Percent_Identity=72.0379146919431, Blast_Score=240, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22951; Mature: 22951

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRALLARELRLAWRSGAEILNPLWFFLIVITLFPFGVGAAPQLLAQIAPGVVWVAALLA
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
ALLVMDRLFRDDWQDGSLEQLMLLPTPLVAVVLVKVVAHWMMSGLPLLIVSPLAALLLGM
HHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
SLHDAGVLAMTLLLGTPTLSFLGAVGVGLTVGLKRGGVLLSLLVLPLAVPLLIFATAACQ
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AAAAELPVGGYLAMLAAFLTASATLCPFATAAALRLTVR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRALLARELRLAWRSGAEILNPLWFFLIVITLFPFGVGAAPQLLAQIAPGVVWVAALLA
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
ALLVMDRLFRDDWQDGSLEQLMLLPTPLVAVVLVKVVAHWMMSGLPLLIVSPLAALLLGM
HHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
SLHDAGVLAMTLLLGTPTLSFLGAVGVGLTVGLKRGGVLLSLLVLPLAVPLLIFATAACQ
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AAAAELPVGGYLAMLAAFLTASATLCPFATAAALRLTVR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]