| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is appD [H]
Identifier: 238895066
GI number: 238895066
Start: 2948865
End: 2949845
Strand: Direct
Name: appD [H]
Synonym: KP1_3098
Alternate gene names: 238895066
Gene position: 2948865-2949845 (Clockwise)
Preceding gene: 238895065
Following gene: 238895067
Centisome position: 56.18
GC content: 66.56
Gene sequence:
>981_bases ATGACCACGCCGTTAGTCTCCTTTAATCATCTCTCCGTCTCTTTCGCCGGCGAACGCTCTCGCGTGCGCGCGGTGCAGGA GGTCTCTTTCACCATTCAGGCCGGGCAAACCGTTGGCGTGGTGGGTGAATCCGGCTGCGGCAAAAGCGTCACCGCCATGG CGCTGATGGGCCTCCTGCCGCCGCAGACGGCGCGCATCGACGGCGGCGAGATCCGCTTCGCGGACCGCGATCTGCTGCGG CTGAAAGCCAGACAGATGGCCGATCTGCGCGGTCACCAGCTGGCAATGATTTTTCAGGAACCGATGTCGGCCCTCAACCC GGTGTTGACCATCGGGGAGCAGCTGTGCGAACCGCCGATCCGCCACCTCGGCGCCACGCCGAAAGCCGCCTGGCATCAGG CCATCCAGCTGTTAAGCGAGGTCGGCCTGGCGCGCGGGGACAGCCTGATGACCCGCTATCCTCACCAGCTTTCCGGCGGC ATGCTGCAGCGTGTGATGATCGCCATGGCGCTGAGCTGTCGGCCCAAACTGCTGATCGCCGACGAACCCACCACCGCGCT CGACGTGACCGTGCAGGCGCAGATCCTACGCCTGCTGCGGGATCGGGCCCGGGCCAGCCAGATGGCGATGATGCTGATTA CCCACGACCTGGGGGTGATCGCGCAGATGGCCGAGCAGGTGGTGGTGATGTATGCCGGACGAATTGTGGAACAAGGCGCC ACCGCGGAAGTGCTACGGCATCCTCAGCATCCCTACACGCGGGGGCTGATCGCCTCCCGACCGGTGCCCGGTGAGCGGCG TCGGCGGCTGTACTCAATTCCCGGCCAGGTGCCGGATCTGGCCGCCCTGCCGGCGGGCTGCGCCTTTGCCGGGCGCTGCG AGCGGGCGACGGCGCGCTGCCGGGAGGCGATTCCGCCGCTGCTCGGCGACCGCCAACGTGCTGCCTGCTTTTATAGCGAA TTTGCGGAGGTGACAGCATGA
Upstream 100 bases:
>100_bases TGCCGCCGGGCATCGCCATCTTTATCACCGTGATCGCCATCAACGTGCTGGGCGATGGCCTGCGCGACGCCATGGATCCC AATATGAAACCGAGGCTGAA
Downstream 100 bases:
>100_bases GCGAACCCTATGTCATTGAAGTGGATGGATTGAAAAAATATTTTCCGCTACGCGACGGCCTGTTTGGTCAGCAGACCGGC GAGCTTCGCGCGGTGGACGG
Product: oligopeptide ABC transport system ATP-binding component
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 326; Mature: 325
Protein sequence:
>326_residues MTTPLVSFNHLSVSFAGERSRVRAVQEVSFTIQAGQTVGVVGESGCGKSVTAMALMGLLPPQTARIDGGEIRFADRDLLR LKARQMADLRGHQLAMIFQEPMSALNPVLTIGEQLCEPPIRHLGATPKAAWHQAIQLLSEVGLARGDSLMTRYPHQLSGG MLQRVMIAMALSCRPKLLIADEPTTALDVTVQAQILRLLRDRARASQMAMMLITHDLGVIAQMAEQVVVMYAGRIVEQGA TAEVLRHPQHPYTRGLIASRPVPGERRRRLYSIPGQVPDLAALPAGCAFAGRCERATARCREAIPPLLGDRQRAACFYSE FAEVTA
Sequences:
>Translated_326_residues MTTPLVSFNHLSVSFAGERSRVRAVQEVSFTIQAGQTVGVVGESGCGKSVTAMALMGLLPPQTARIDGGEIRFADRDLLR LKARQMADLRGHQLAMIFQEPMSALNPVLTIGEQLCEPPIRHLGATPKAAWHQAIQLLSEVGLARGDSLMTRYPHQLSGG MLQRVMIAMALSCRPKLLIADEPTTALDVTVQAQILRLLRDRARASQMAMMLITHDLGVIAQMAEQVVVMYAGRIVEQGA TAEVLRHPQHPYTRGLIASRPVPGERRRRLYSIPGQVPDLAALPAGCAFAGRCERATARCREAIPPLLGDRQRAACFYSE FAEVTA >Mature_325_residues TTPLVSFNHLSVSFAGERSRVRAVQEVSFTIQAGQTVGVVGESGCGKSVTAMALMGLLPPQTARIDGGEIRFADRDLLRL KARQMADLRGHQLAMIFQEPMSALNPVLTIGEQLCEPPIRHLGATPKAAWHQAIQLLSEVGLARGDSLMTRYPHQLSGGM LQRVMIAMALSCRPKLLIADEPTTALDVTVQAQILRLLRDRARASQMAMMLITHDLGVIAQMAEQVVVMYAGRIVEQGAT AEVLRHPQHPYTRGLIASRPVPGERRRRLYSIPGQVPDLAALPAGCAFAGRCERATARCREAIPPLLGDRQRAACFYSEF AEVTA
Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI9961250, Length=250, Percent_Identity=31.6, Blast_Score=97, Evalue=3e-20, Organism=Homo sapiens, GI4505771, Length=250, Percent_Identity=31.6, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI9961252, Length=250, Percent_Identity=31.6, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI255708477, Length=233, Percent_Identity=32.1888412017167, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI148612844, Length=233, Percent_Identity=32.1888412017167, Blast_Score=89, Evalue=8e-18, Organism=Homo sapiens, GI42741659, Length=236, Percent_Identity=31.3559322033898, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI21536378, Length=233, Percent_Identity=28.755364806867, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI9665248, Length=248, Percent_Identity=29.4354838709677, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI171184400, Length=253, Percent_Identity=30.0395256916996, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI9955968, Length=245, Percent_Identity=29.3877551020408, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI9955966, Length=245, Percent_Identity=29.3877551020408, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI45243524, Length=245, Percent_Identity=29.3877551020408, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI150417984, Length=260, Percent_Identity=28.4615384615385, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI156105685, Length=254, Percent_Identity=29.5275590551181, Blast_Score=68, Evalue=9e-12, Organism=Escherichia coli, GI1787759, Length=323, Percent_Identity=48.6068111455108, Blast_Score=300, Evalue=1e-82, Organism=Escherichia coli, GI1789963, Length=316, Percent_Identity=45.8860759493671, Blast_Score=285, Evalue=3e-78, Organism=Escherichia coli, GI48994883, Length=303, Percent_Identity=47.1947194719472, Blast_Score=273, Evalue=8e-75, Organism=Escherichia coli, GI145693107, Length=262, Percent_Identity=47.7099236641221, Blast_Score=247, Evalue=9e-67, Organism=Escherichia coli, GI1788506, Length=261, Percent_Identity=47.5095785440613, Blast_Score=230, Evalue=1e-61, Organism=Escherichia coli, GI1787548, Length=309, Percent_Identity=40.453074433657, Blast_Score=223, Evalue=1e-59, Organism=Escherichia coli, GI1787500, Length=301, Percent_Identity=37.8737541528239, Blast_Score=205, Evalue=3e-54, Organism=Escherichia coli, GI1789962, Length=307, Percent_Identity=38.4364820846906, Blast_Score=204, Evalue=6e-54, Organism=Escherichia coli, GI1787758, Length=314, Percent_Identity=35.6687898089172, Blast_Score=177, Evalue=1e-45, Organism=Escherichia coli, GI1789890, Length=236, Percent_Identity=41.5254237288136, Blast_Score=154, Evalue=5e-39, Organism=Escherichia coli, GI48994997, Length=265, Percent_Identity=35.8490566037736, Blast_Score=145, Evalue=5e-36, Organism=Escherichia coli, GI1787547, Length=266, Percent_Identity=33.4586466165414, Blast_Score=143, Evalue=1e-35, Organism=Escherichia coli, GI1789891, Length=232, Percent_Identity=38.7931034482759, Blast_Score=139, Evalue=4e-34, Organism=Escherichia coli, GI1786398, Length=275, Percent_Identity=33.4545454545455, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1788225, Length=230, Percent_Identity=33.0434782608696, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1787029, Length=249, Percent_Identity=31.3253012048193, Blast_Score=108, Evalue=5e-25, Organism=Escherichia coli, GI1789672, Length=240, Percent_Identity=31.6666666666667, Blast_Score=108, Evalue=6e-25, Organism=Escherichia coli, GI1787089, Length=229, Percent_Identity=35.3711790393013, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1788644, Length=187, Percent_Identity=34.2245989304813, Blast_Score=104, Evalue=8e-24, Organism=Escherichia coli, GI1788450, Length=255, Percent_Identity=31.3725490196078, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI1787105, Length=239, Percent_Identity=36.4016736401674, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI87081791, Length=257, Percent_Identity=32.295719844358, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI1788761, Length=237, Percent_Identity=34.1772151898734, Blast_Score=101, Evalue=7e-23, Organism=Escherichia coli, GI1789873, Length=231, Percent_Identity=32.034632034632, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1786872, Length=220, Percent_Identity=32.7272727272727, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87081834, Length=239, Percent_Identity=31.3807531380753, Blast_Score=98, Evalue=8e-22, Organism=Escherichia coli, GI1789032, Length=231, Percent_Identity=28.1385281385281, Blast_Score=98, Evalue=9e-22, Organism=Escherichia coli, GI1787370, Length=257, Percent_Identity=28.0155642023346, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1786703, Length=218, Percent_Identity=31.651376146789, Blast_Score=91, Evalue=2e-19, Organism=Escherichia coli, GI87081709, Length=227, Percent_Identity=28.6343612334802, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1790162, Length=254, Percent_Identity=27.1653543307087, Blast_Score=88, Evalue=9e-19, Organism=Escherichia coli, GI1786563, Length=276, Percent_Identity=29.3478260869565, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787712, Length=260, Percent_Identity=27.6923076923077, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1790739, Length=244, Percent_Identity=28.6885245901639, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787112, Length=246, Percent_Identity=30.8943089430894, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1790467, Length=236, Percent_Identity=30.0847457627119, Blast_Score=84, Evalue=2e-17, Organism=Escherichia coli, GI1786253, Length=221, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786345, Length=290, Percent_Identity=27.2413793103448, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1787792, Length=254, Percent_Identity=30.3149606299213, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI87082267, Length=240, Percent_Identity=27.0833333333333, Blast_Score=78, Evalue=1e-15, Organism=Escherichia coli, GI1788210, Length=250, Percent_Identity=27.6, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1790190, Length=233, Percent_Identity=27.0386266094421, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787143, Length=251, Percent_Identity=30.6772908366534, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1786698, Length=218, Percent_Identity=27.5229357798165, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786319, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787164, Length=234, Percent_Identity=30.3418803418803, Blast_Score=70, Evalue=3e-13, Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=24.5136186770428, Blast_Score=70, Evalue=3e-13, Organism=Escherichia coli, GI1786803, Length=229, Percent_Identity=27.0742358078603, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789586, Length=242, Percent_Identity=26.0330578512397, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI48995001, Length=237, Percent_Identity=28.2700421940928, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI1790544, Length=242, Percent_Identity=28.9256198347107, Blast_Score=68, Evalue=9e-13, Organism=Escherichia coli, GI1789991, Length=240, Percent_Identity=24.5833333333333, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789593, Length=228, Percent_Identity=26.7543859649123, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1788053, Length=197, Percent_Identity=29.4416243654822, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1790534, Length=214, Percent_Identity=28.0373831775701, Blast_Score=63, Evalue=3e-11, Organism=Caenorhabditis elegans, GI115534520, Length=277, Percent_Identity=27.7978339350181, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI193208177, Length=262, Percent_Identity=27.4809160305344, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI193202349, Length=241, Percent_Identity=32.7800829875519, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17567265, Length=240, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI212646699, Length=246, Percent_Identity=27.6422764227642, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193209708, Length=240, Percent_Identity=30, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17558664, Length=235, Percent_Identity=31.9148936170213, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI193211015, Length=224, Percent_Identity=29.9107142857143, Blast_Score=76, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193211017, Length=224, Percent_Identity=29.9107142857143, Blast_Score=76, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71996809, Length=244, Percent_Identity=26.6393442622951, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17569145, Length=236, Percent_Identity=29.2372881355932, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17569143, Length=241, Percent_Identity=30.2904564315353, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI115535101, Length=252, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25146777, Length=233, Percent_Identity=28.3261802575107, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567269, Length=230, Percent_Identity=31.7391304347826, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71984940, Length=226, Percent_Identity=28.3185840707965, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71992290, Length=274, Percent_Identity=25.1824817518248, Blast_Score=65, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324985, Length=270, Percent_Identity=27.4074074074074, Blast_Score=86, Evalue=7e-18, Organism=Saccharomyces cerevisiae, GI6323217, Length=257, Percent_Identity=26.0700389105058, Blast_Score=74, Evalue=3e-14, Organism=Drosophila melanogaster, GI24659289, Length=246, Percent_Identity=32.520325203252, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI85726357, Length=254, Percent_Identity=27.9527559055118, Blast_Score=79, Evalue=6e-15, Organism=Drosophila melanogaster, GI17136662, Length=224, Percent_Identity=31.6964285714286, Blast_Score=76, Evalue=4e-14, Organism=Drosophila melanogaster, GI28574533, Length=239, Percent_Identity=29.2887029288703, Blast_Score=75, Evalue=9e-14, Organism=Drosophila melanogaster, GI281363262, Length=241, Percent_Identity=29.4605809128631, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24653245, Length=238, Percent_Identity=28.9915966386555, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI85724864, Length=235, Percent_Identity=27.2340425531915, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24580555, Length=235, Percent_Identity=27.2340425531915, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI85816269, Length=235, Percent_Identity=27.2340425531915, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24580553, Length=235, Percent_Identity=27.2340425531915, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 35506; Mature: 35375
Theoretical pI: Translated: 9.38; Mature: 9.38
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 4.6 %Met (Translated Protein) 6.7 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 4.3 %Met (Mature Protein) 6.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTPLVSFNHLSVSFAGERSRVRAVQEVSFTIQAGQTVGVVGESGCGKSVTAMALMGLLP CCCCCEEECCEEEEECCCHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHHHHHHCCC PQTARIDGGEIRFADRDLLRLKARQMADLRGHQLAMIFQEPMSALNPVLTIGEQLCEPPI CCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH RHLGATPKAAWHQAIQLLSEVGLARGDSLMTRYPHQLSGGMLQRVMIAMALSCRPKLLIA HHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEE DEPTTALDVTVQAQILRLLRDRARASQMAMMLITHDLGVIAQMAEQVVVMYAGRIVEQGA CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC TAEVLRHPQHPYTRGLIASRPVPGERRRRLYSIPGQVPDLAALPAGCAFAGRCERATARC HHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHH REAIPPLLGDRQRAACFYSEFAEVTA HHHCCCCCCCCHHHHHHHHHHHHHCC >Mature Secondary Structure TTPLVSFNHLSVSFAGERSRVRAVQEVSFTIQAGQTVGVVGESGCGKSVTAMALMGLLP CCCCEEECCEEEEECCCHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHHHHHHHHCCC PQTARIDGGEIRFADRDLLRLKARQMADLRGHQLAMIFQEPMSALNPVLTIGEQLCEPPI CCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH RHLGATPKAAWHQAIQLLSEVGLARGDSLMTRYPHQLSGGMLQRVMIAMALSCRPKLLIA HHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEE DEPTTALDVTVQAQILRLLRDRARASQMAMMLITHDLGVIAQMAEQVVVMYAGRIVEQGA CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC TAEVLRHPQHPYTRGLIASRPVPGERRRRLYSIPGQVPDLAALPAGCAFAGRCERATARC HHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHH REAIPPLLGDRQRAACFYSEFAEVTA HHHCCCCCCCCHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 7997159; 9384377 [H]