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The map label for this gene is xylB [H]

Identifier: 238894986

GI number: 238894986

Start: 2873961

End: 2875049

Strand: Direct

Name: xylB [H]

Synonym: KP1_3012

Alternate gene names: 238894986

Gene position: 2873961-2875049 (Clockwise)

Preceding gene: 238894983

Following gene: 238894989

Centisome position: 54.76

GC content: 60.15

Gene sequence:

>1089_bases
ATGCAAGTGAAAGCAGCCGTCACGCTGGGCTACCAGCAGCCTTTTGTCATCAAAGACGTCGAGGTCGCCCCGCCGGGGAA
GGACGAGATATTAGTGAAAATTGTCGCCACCGGCGTCTGCCATACCGACGCCGTGATGCGCGACAACCCCGGGGTGGTGC
CTATGCCGGCGATCCTCGGCCATGAAGGCGCCGGGATCGTTGCCAGCGTCGGCGAGGCGGTTAGCGGCATCAGAGTAGGA
GACCACGTGGTGCTCAGCTACGCCGCCTGCCACCACTGCGAAAATTGTTTAAGCAACCACCCTTCGGCTTGCGAAGATTT
TAATACGCTTAATTTTGGCGGCCGACGCGAGGATGGCACCACCCCCTACCGGCTGGGAGACCAGGATCTGTCCCTGTTCT
TTGGCCAGTCGTCTTTCAGCCAGTATGTGGTCACCCGCGCCAGCAACGCGGTCGTGGTCGACCCGGAGGTTGATCTCACC
CTGCTCGGCCCGCTGGGTTGCGGTATCCAGACCGGTAGCGGGACGGTGCTCAACCGCCTGAAACCGGTGGTCGGCGAATC
GCTGGTGGTGTTTGGCTGCGGCGCGGTGGGGCTCAGCGCCATCATGGCAGCGAAATTAACCGGCTGTTCGCAGATTATCG
CGGTGGATATCCATGCCAGCCGCCTCGCCCTGGCGGGCGAACTGGGCGCGACCCATCAGATCAATGGCAAGGAACAGGAT
GCCGTCGCCGTGATTAAACAAATCACCGGTAAAGGCGCCCACTACGCGGTGGAAACGACCGGCGTCTCCGCTATCGTTCT
GCAGGCCGTACACGCGGTGAAACCGCTGGGAACGGTGGCGATTGTGGGCTTTACCGGAGATATCACCCTTAACGTGCAGA
ACGACCTGATGGCGGAGGGAAAATCGCTGGTCGGGGTGATTGAAGGCGACGCCGTGCCGGCGTTGTTTATTCCGCTGTTG
GTTCAACTCTATAAACAGGGAAAATTCCCTATCGATAAGCTTATCGCCCGCTATCCGTTGGCCGATATCAACCAGGCCTT
CGCCGATTCGGCGTCCGGCAAGGTGATCAAGCCGGTGGTGGTCATGTGA

Upstream 100 bases:

>100_bases
CCCGATAACCGCTATCTTTCTTCACGTTAGCGGCCAACAGGGGAGAGCCGTTCGGGCTGTCCCGCCACGCTCTCCAGGGA
ATTCAATCAGGAGTCATGCC

Downstream 100 bases:

>100_bases
GATAACGTCGCCACCGGTCGGTGGCGACAGTTGCGCATTATGGGATTTATTCCAGCGTCACGTGATGCTTCATCACCCGG
CGAAACAGCGCCAGTCTGGC

Product: Zinc-containing alcohol dehydrogenase superfamily

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MQVKAAVTLGYQQPFVIKDVEVAPPGKDEILVKIVATGVCHTDAVMRDNPGVVPMPAILGHEGAGIVASVGEAVSGIRVG
DHVVLSYAACHHCENCLSNHPSACEDFNTLNFGGRREDGTTPYRLGDQDLSLFFGQSSFSQYVVTRASNAVVVDPEVDLT
LLGPLGCGIQTGSGTVLNRLKPVVGESLVVFGCGAVGLSAIMAAKLTGCSQIIAVDIHASRLALAGELGATHQINGKEQD
AVAVIKQITGKGAHYAVETTGVSAIVLQAVHAVKPLGTVAIVGFTGDITLNVQNDLMAEGKSLVGVIEGDAVPALFIPLL
VQLYKQGKFPIDKLIARYPLADINQAFADSASGKVIKPVVVM

Sequences:

>Translated_362_residues
MQVKAAVTLGYQQPFVIKDVEVAPPGKDEILVKIVATGVCHTDAVMRDNPGVVPMPAILGHEGAGIVASVGEAVSGIRVG
DHVVLSYAACHHCENCLSNHPSACEDFNTLNFGGRREDGTTPYRLGDQDLSLFFGQSSFSQYVVTRASNAVVVDPEVDLT
LLGPLGCGIQTGSGTVLNRLKPVVGESLVVFGCGAVGLSAIMAAKLTGCSQIIAVDIHASRLALAGELGATHQINGKEQD
AVAVIKQITGKGAHYAVETTGVSAIVLQAVHAVKPLGTVAIVGFTGDITLNVQNDLMAEGKSLVGVIEGDAVPALFIPLL
VQLYKQGKFPIDKLIARYPLADINQAFADSASGKVIKPVVVM
>Mature_362_residues
MQVKAAVTLGYQQPFVIKDVEVAPPGKDEILVKIVATGVCHTDAVMRDNPGVVPMPAILGHEGAGIVASVGEAVSGIRVG
DHVVLSYAACHHCENCLSNHPSACEDFNTLNFGGRREDGTTPYRLGDQDLSLFFGQSSFSQYVVTRASNAVVVDPEVDLT
LLGPLGCGIQTGSGTVLNRLKPVVGESLVVFGCGAVGLSAIMAAKLTGCSQIIAVDIHASRLALAGELGATHQINGKEQD
AVAVIKQITGKGAHYAVETTGVSAIVLQAVHAVKPLGTVAIVGFTGDITLNVQNDLMAEGKSLVGVIEGDAVPALFIPLL
VQLYKQGKFPIDKLIARYPLADINQAFADSASGKVIKPVVVM

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=36.1413043478261, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=35.8695652173913, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=35.054347826087, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI71565152, Length=373, Percent_Identity=33.2439678284182, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI71565154, Length=370, Percent_Identity=35.1351351351351, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI156523966, Length=371, Percent_Identity=32.6145552560647, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI71743840, Length=368, Percent_Identity=31.7934782608696, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI262073058, Length=368, Percent_Identity=31.7934782608696, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI4501939, Length=363, Percent_Identity=33.0578512396694, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1786552, Length=368, Percent_Identity=33.1521739130435, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788073, Length=354, Percent_Identity=28.2485875706215, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082125, Length=360, Percent_Identity=26.6666666666667, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87081918, Length=340, Percent_Identity=30.5882352941176, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790045, Length=290, Percent_Identity=25.8620689655172, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788407, Length=264, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788075, Length=311, Percent_Identity=28.2958199356913, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI226510992, Length=345, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787863, Length=325, Percent_Identity=25.2307692307692, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25146526, Length=376, Percent_Identity=35.3723404255319, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI71997431, Length=378, Percent_Identity=35.1851851851852, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17565904, Length=331, Percent_Identity=35.6495468277946, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17562878, Length=355, Percent_Identity=28.7323943661972, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17562876, Length=354, Percent_Identity=26.5536723163842, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17562584, Length=287, Percent_Identity=29.9651567944251, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562582, Length=290, Percent_Identity=27.9310344827586, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=289, Percent_Identity=28.0276816608997, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=369, Percent_Identity=33.8753387533875, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6319621, Length=281, Percent_Identity=30.2491103202847, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=277, Percent_Identity=29.9638989169675, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6324486, Length=277, Percent_Identity=29.6028880866426, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323961, Length=277, Percent_Identity=29.2418772563177, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319258, Length=307, Percent_Identity=24.1042345276873, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737895, Length=371, Percent_Identity=33.4231805929919, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI17737897, Length=339, Percent_Identity=26.5486725663717, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17137530, Length=234, Percent_Identity=29.4871794871795, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 37624; Mature: 37624

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKAAVTLGYQQPFVIKDVEVAPPGKDEILVKIVATGVCHTDAVMRDNPGVVPMPAILG
CCEEEEEEECCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCEECCCCCCCCCHHHHC
HEGAGIVASVGEAVSGIRVGDHVVLSYAACHHCENCLSNHPSACEDFNTLNFGGRREDGT
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCC
TPYRLGDQDLSLFFGQSSFSQYVVTRASNAVVVDPEVDLTLLGPLGCGIQTGSGTVLNRL
CCCEECCCCEEEEECCCCHHHHHEEECCCEEEECCCCCEEEECCCCCCEECCCCHHHHHH
KPVVGESLVVFGCGAVGLSAIMAAKLTGCSQIIAVDIHASRLALAGELGATHQINGKEQD
HHHHCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEEHHHHEEHHCCCCCEECCCCCHH
AVAVIKQITGKGAHYAVETTGVSAIVLQAVHAVKPLGTVAIVGFTGDITLNVQNDLMAEG
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECEEEEEECHHHHHCC
KSLVGVIEGDAVPALFIPLLVQLYKQGKFPIDKLIARYPLADINQAFADSASGKVIKPVV
CCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCCCEECCEE
VM
EC
>Mature Secondary Structure
MQVKAAVTLGYQQPFVIKDVEVAPPGKDEILVKIVATGVCHTDAVMRDNPGVVPMPAILG
CCEEEEEEECCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCEECCCCCCCCCHHHHC
HEGAGIVASVGEAVSGIRVGDHVVLSYAACHHCENCLSNHPSACEDFNTLNFGGRREDGT
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCC
TPYRLGDQDLSLFFGQSSFSQYVVTRASNAVVVDPEVDLTLLGPLGCGIQTGSGTVLNRL
CCCEECCCCEEEEECCCCHHHHHEEECCCEEEECCCCCEEEECCCCCCEECCCCHHHHHH
KPVVGESLVVFGCGAVGLSAIMAAKLTGCSQIIAVDIHASRLALAGELGATHQINGKEQD
HHHHCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEEHHHHEEHHCCCCCEECCCCCHH
AVAVIKQITGKGAHYAVETTGVSAIVLQAVHAVKPLGTVAIVGFTGDITLNVQNDLMAEG
HHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECEEEEEECHHHHHCC
KSLVGVIEGDAVPALFIPLLVQLYKQGKFPIDKLIARYPLADINQAFADSASGKVIKPVV
CCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCCCCEECCEE
VM
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]