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The map label for this gene is ydcR [H]

Identifier: 238894968

GI number: 238894968

Start: 2856164

End: 2857576

Strand: Reverse

Name: ydcR [H]

Synonym: KP1_2994

Alternate gene names: 238894968

Gene position: 2857576-2856164 (Counterclockwise)

Preceding gene: 238894969

Following gene: 238894967

Centisome position: 54.45

GC content: 61.71

Gene sequence:

>1413_bases
ATGAAAAAGTATCAACAGTTGGCGCAGCAACTGACCGAGCAGATCGCCCTTGGCGTCTGGTTGCCTGGAGATCGGCTGCC
GTCGCTGCGCGAGCAGGTGATCAGCAGCGGCATGAGCTTTATGACCGTCAGCCATGCCTATCAGCTGCTGGAAAGCCAGG
GGCGCATCGTCGCCCGTCCGCAGTCGGGTTATTATGTTGCCCCCCAGCCGGTGAAGCTCCGCCAGCCGGCGCCGCCTGCC
CAGGTCACTCGCGATGAAGCCGTCGATATCAATACCTATATCTTTGAGGTGCTCCAGGCCAGCCGCCAGGCGTCGATGCT
GCCCTTTGCCTCGGCCTTTCCGGACCCGCGTCTCTTCCCGCTGCAGCAGCTCAACCGCTCGCTGGCGCAGGTGAGTAAAA
CCGCCACCGCCATGAGCGTCATTGAGAATCTGCCGCCGGGCAATGCAGAACTCCGGCATGCCATTGCCCGTCGCTATGCC
CTGCAGGGGATGAACGTCTCGCCGGACGAGATCGTCATCACCGCCGGGGCGCTGGAGGCGCTTAACCTCAGCCTGCAGGC
GGTGACCGAGCCGGGAGACTGGGTGGTGGTGGAAAACCCCTGCTTCTACGGCGCCCTGCAGGCGCTGGAGAGGCTGCGTT
TGAAAGCATTGTCGGTGGCCACTGACGTCAGGGAAGGCATTGATCTGACGGCGCTGGAGGCGGCCCTGCAAAACTATCCG
GTGAAGGCCTGCTGGCTGATGACCAACGGCCAGAATCCGCTCGGCTTCACCCTCAGCGCTGAAAAAAAAGCGGCGCTGGT
GGCGCTGCTGGCGCGCTATAACGTGATGTTGATCGAAGATGATGTCTACAGCGAGCTCTATTTTGGCCGCGAAAAGCCGT
TACCGGCGAAGTTCTGGGATCGCCAGGAGATGACGCTGCACTGCAGCTCGTTCTCAAAATGTCTGGTACCCGGCTTTCGT
ATCGGCTGGGTGGCGGCCGGCAAACAGGCGCGGCGGATCCAGCAGCTCCAGCTGATGAGTACGCTTTCCACCAGTTCGCC
GATGCAGTTAGCCCTGGTGGATTACCTGTCCACCAAGCGCTATGACGCCCACCTGCGCCGTCTACGTCGTCAGCTGGCGG
AGCGTAAACAGCAGGCCTGGCAGGCGCTGCTGCGCCATCTGCCGCCGGAGGTCATCGTCCACCACAGCGACAGTGGCTAC
TTTCTGTGGATCGAACTACCGGAAGGGGCCGACGCTAGTGCACTTAGCGCCCGGGCGCTTGCGTCGCACATCAGTATTGC
CCCAGGGAAAATGTTCTCCACCTCCGACAGCTGGACCTCGTTTTTCCGTTTTAATACCGCCTGGGGCTGGGGGAAACGCG
AAGAGCAGGGGGTGAAGCGCCTGGGGGAGCTTATTCGCGAACAGCTTGCCTGA

Upstream 100 bases:

>100_bases
GCGACGCGGCCGCCGCTGCAGATATAACAGTTACAGGAAACTATGATTTTTTTATAACTGATATATGATAATGGGACGTT
ATCGTACGGGGACGGCCGCA

Downstream 100 bases:

>100_bases
CCCTGTCGTTTATTTTTCTCATCATAAACATTCTGCGAAAATAAGCGAAAGAGGATTTTTATCGAGGCCGGTCATTATTT
TACCGGCGCTCACCATAGGA

Product: bifunctional putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MKKYQQLAQQLTEQIALGVWLPGDRLPSLREQVISSGMSFMTVSHAYQLLESQGRIVARPQSGYYVAPQPVKLRQPAPPA
QVTRDEAVDINTYIFEVLQASRQASMLPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRHAIARRYA
LQGMNVSPDEIVITAGALEALNLSLQAVTEPGDWVVVENPCFYGALQALERLRLKALSVATDVREGIDLTALEAALQNYP
VKACWLMTNGQNPLGFTLSAEKKAALVALLARYNVMLIEDDVYSELYFGREKPLPAKFWDRQEMTLHCSSFSKCLVPGFR
IGWVAAGKQARRIQQLQLMSTLSTSSPMQLALVDYLSTKRYDAHLRRLRRQLAERKQQAWQALLRHLPPEVIVHHSDSGY
FLWIELPEGADASALSARALASHISIAPGKMFSTSDSWTSFFRFNTAWGWGKREEQGVKRLGELIREQLA

Sequences:

>Translated_470_residues
MKKYQQLAQQLTEQIALGVWLPGDRLPSLREQVISSGMSFMTVSHAYQLLESQGRIVARPQSGYYVAPQPVKLRQPAPPA
QVTRDEAVDINTYIFEVLQASRQASMLPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRHAIARRYA
LQGMNVSPDEIVITAGALEALNLSLQAVTEPGDWVVVENPCFYGALQALERLRLKALSVATDVREGIDLTALEAALQNYP
VKACWLMTNGQNPLGFTLSAEKKAALVALLARYNVMLIEDDVYSELYFGREKPLPAKFWDRQEMTLHCSSFSKCLVPGFR
IGWVAAGKQARRIQQLQLMSTLSTSSPMQLALVDYLSTKRYDAHLRRLRRQLAERKQQAWQALLRHLPPEVIVHHSDSGY
FLWIELPEGADASALSARALASHISIAPGKMFSTSDSWTSFFRFNTAWGWGKREEQGVKRLGELIREQLA
>Mature_470_residues
MKKYQQLAQQLTEQIALGVWLPGDRLPSLREQVISSGMSFMTVSHAYQLLESQGRIVARPQSGYYVAPQPVKLRQPAPPA
QVTRDEAVDINTYIFEVLQASRQASMLPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRHAIARRYA
LQGMNVSPDEIVITAGALEALNLSLQAVTEPGDWVVVENPCFYGALQALERLRLKALSVATDVREGIDLTALEAALQNYP
VKACWLMTNGQNPLGFTLSAEKKAALVALLARYNVMLIEDDVYSELYFGREKPLPAKFWDRQEMTLHCSSFSKCLVPGFR
IGWVAAGKQARRIQQLQLMSTLSTSSPMQLALVDYLSTKRYDAHLRRLRRQLAERKQQAWQALLRHLPPEVIVHHSDSGY
FLWIELPEGADASALSARALASHISIAPGKMFSTSDSWTSFFRFNTAWGWGKREEQGVKRLGELIREQLA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=397, Percent_Identity=24.9370277078086, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI33469970, Length=397, Percent_Identity=24.9370277078086, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507369, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787710, Length=469, Percent_Identity=83.3688699360341, Blast_Score=805, Evalue=0.0,
Organism=Escherichia coli, GI1790797, Length=468, Percent_Identity=33.7606837606838, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI1788722, Length=314, Percent_Identity=24.8407643312102, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=179, Percent_Identity=26.8156424581006, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=365, Percent_Identity=21.0958904109589, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356535, Length=353, Percent_Identity=22.9461756373938, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI18859735, Length=222, Percent_Identity=26.1261261261261, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52577; Mature: 52577

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQQLAQQLTEQIALGVWLPGDRLPSLREQVISSGMSFMTVSHAYQLLESQGRIVARP
CCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECC
QSGYYVAPQPVKLRQPAPPAQVTRDEAVDINTYIFEVLQASRQASMLPFASAFPDPRLFP
CCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC
LQQLNRSLAQVSKTATAMSVIENLPPGNAELRHAIARRYALQGMNVSPDEIVITAGALEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHH
LNLSLQAVTEPGDWVVVENPCFYGALQALERLRLKALSVATDVREGIDLTALEAALQNYP
HCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
VKACWLMTNGQNPLGFTLSAEKKAALVALLARYNVMLIEDDVYSELYFGREKPLPAKFWD
CEEEEEEECCCCCCEEEECCCHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCHHHCC
RQEMTLHCSSFSKCLVPGFRIGWVAAGKQARRIQQLQLMSTLSTSSPMQLALVDYLSTKR
CCCEEEEHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YDAHLRRLRRQLAERKQQAWQALLRHLPPEVIVHHSDSGYFLWIELPEGADASALSARAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCEEEEEECCCCCCHHHHHHHHH
ASHISIAPGKMFSTSDSWTSFFRFNTAWGWGKREEQGVKRLGELIREQLA
HHHHCCCCCCCCCCCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYQQLAQQLTEQIALGVWLPGDRLPSLREQVISSGMSFMTVSHAYQLLESQGRIVARP
CCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECC
QSGYYVAPQPVKLRQPAPPAQVTRDEAVDINTYIFEVLQASRQASMLPFASAFPDPRLFP
CCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCC
LQQLNRSLAQVSKTATAMSVIENLPPGNAELRHAIARRYALQGMNVSPDEIVITAGALEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHH
LNLSLQAVTEPGDWVVVENPCFYGALQALERLRLKALSVATDVREGIDLTALEAALQNYP
HCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
VKACWLMTNGQNPLGFTLSAEKKAALVALLARYNVMLIEDDVYSELYFGREKPLPAKFWD
CEEEEEEECCCCCCEEEECCCHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCHHHCC
RQEMTLHCSSFSKCLVPGFRIGWVAAGKQARRIQQLQLMSTLSTSSPMQLALVDYLSTKR
CCCEEEEHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YDAHLRRLRRQLAERKQQAWQALLRHLPPEVIVHHSDSGYFLWIELPEGADASALSARAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCEEEEEECCCCCCHHHHHHHHH
ASHISIAPGKMFSTSDSWTSFFRFNTAWGWGKREEQGVKRLGELIREQLA
HHHHCCCCCCCCCCCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]