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The map label for this gene is celB [H]

Identifier: 238894867

GI number: 238894867

Start: 2753906

End: 2755186

Strand: Reverse

Name: celB [H]

Synonym: KP1_2884

Alternate gene names: 238894867

Gene position: 2755186-2753906 (Counterclockwise)

Preceding gene: 238894868

Following gene: 238894866

Centisome position: 52.49

GC content: 45.59

Gene sequence:

>1281_bases
ATGTCATCTCATACCAACATTGTACAAGAAAAGGCTTTGCAACTGATGCAAAGCATTGGTCAAAATACCTACCTTAAGTC
AATCATGAGCGGTATGATGCTCATATTGCCAGTAACGATCATGAGTTCTGTGGCGACTTTGGTTAAAGTGTTTCCGTTTG
CTCCATATCAGGATTTTTTGTTACGACACAACTTAACTCGCTTCTTTGATATCCCGATTACCTTCACGAATAATTTTTTG
GCCGTGATTGTCGCTTTCTCCGTTGCCTATACGCTAGCGAAAAATTTCGATGTTGATGGCTTCATGTCAGGCCTGATTTC
AATGATCTCTTTCTTTATTTTAACGCCGTATGATCTCGGTGAAATAGGGCCGTTAGGACAATCATTTTCAATTCCTGGCC
AATGGCTGGGGCCCATGGGGCTGTTTACCGCAATTCTGGTGGCGATAATTTCAACACGAATATTCGTGGCGATAACTCGC
AAGGGGTTGATTATCAAAATGCCAGAAAATGTCCCTGAATTTATCTCCAAATCGTTCTCTTCATTGATTCCAGGAATCGC
CATCCTGACGCTGTTTACAATTATCTCCGCAGTCATTACCAGCGTTGGTTATGGGAGCATTCACGAAATTATTTATAAAT
TAATCCAGGTTCCGCTAACATCACTTGGATCCGGAATCTGGTCACTCATCTTTGTTGCTGTTGTTGCGCAATTGCTATGG
TTTTTTGGGCTGCATGGCCACGCTATCACCCTCGGTATCGTAGCGCCGATCTGGTTTGCCATGGATGCCCAGCAGCTTGC
TGCGTATGCTGCAGGCGTCGACTTACCCAACATCACCGGCTTTGCGTTCTTTATGACTTATGGCGCTGCTGGAGATTTAT
TGCCGCTGGCTATAATGCTCGCTTTTTTCGCGAAGAGCGCACGCTATAAAACGCTCGGTAAGATCGCCTTGCCGCCAGCT
ATCTTCACCATTGGCGAACCGATGGCTTATGGTGTGCCGCTGGTAATGAATTTTACTCTGGCGATTCCTTATATTTTTAT
CAATGGCATCATGCTCGGCATTGCATGGTATCTAACGGTCATTGGCGTATTGCCTCGCGTCGCTGGGGTGAGTACCCCGG
CCGGCATGCCGATCATTATTTCTGGTTTTATGCAGGGGAGCTGGAAAATTGCCGCTTTCCAATTTATAGGACTTTTTGCG
CGATTTGCAGGTTGGTATTTCTTCTTCAAGACTGCCGATCTTGTCGCTTGCCGGGAAGAAAATCAGACGGATACCATTTG
A

Upstream 100 bases:

>100_bases
GGCTGACTTCCTGGTTAGATTATGATGCATTAATGTCATGCCGGCATATGAATTCTTAAATGAATATGTCTGAAAACTAA
TAATATCACGGACTGTTTAC

Downstream 100 bases:

>100_bases
ATGCTCCTTAAAAAAATGCCAGCAACGCCAATTTAGCCATGGTGGGAAAGATGTTAAGTATGAATTACCAAACGGAAAAC
ATTATTGTCGATCATCTGCC

Product: cellobiose-specific PTS family enzyme IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Cel; PTS system cellobiose-specific EIIC component [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSSHTNIVQEKALQLMQSIGQNTYLKSIMSGMMLILPVTIMSSVATLVKVFPFAPYQDFLLRHNLTRFFDIPITFTNNFL
AVIVAFSVAYTLAKNFDVDGFMSGLISMISFFILTPYDLGEIGPLGQSFSIPGQWLGPMGLFTAILVAIISTRIFVAITR
KGLIIKMPENVPEFISKSFSSLIPGIAILTLFTIISAVITSVGYGSIHEIIYKLIQVPLTSLGSGIWSLIFVAVVAQLLW
FFGLHGHAITLGIVAPIWFAMDAQQLAAYAAGVDLPNITGFAFFMTYGAAGDLLPLAIMLAFFAKSARYKTLGKIALPPA
IFTIGEPMAYGVPLVMNFTLAIPYIFINGIMLGIAWYLTVIGVLPRVAGVSTPAGMPIIISGFMQGSWKIAAFQFIGLFA
RFAGWYFFFKTADLVACREENQTDTI

Sequences:

>Translated_426_residues
MSSHTNIVQEKALQLMQSIGQNTYLKSIMSGMMLILPVTIMSSVATLVKVFPFAPYQDFLLRHNLTRFFDIPITFTNNFL
AVIVAFSVAYTLAKNFDVDGFMSGLISMISFFILTPYDLGEIGPLGQSFSIPGQWLGPMGLFTAILVAIISTRIFVAITR
KGLIIKMPENVPEFISKSFSSLIPGIAILTLFTIISAVITSVGYGSIHEIIYKLIQVPLTSLGSGIWSLIFVAVVAQLLW
FFGLHGHAITLGIVAPIWFAMDAQQLAAYAAGVDLPNITGFAFFMTYGAAGDLLPLAIMLAFFAKSARYKTLGKIALPPA
IFTIGEPMAYGVPLVMNFTLAIPYIFINGIMLGIAWYLTVIGVLPRVAGVSTPAGMPIIISGFMQGSWKIAAFQFIGLFA
RFAGWYFFFKTADLVACREENQTDTI
>Mature_425_residues
SSHTNIVQEKALQLMQSIGQNTYLKSIMSGMMLILPVTIMSSVATLVKVFPFAPYQDFLLRHNLTRFFDIPITFTNNFLA
VIVAFSVAYTLAKNFDVDGFMSGLISMISFFILTPYDLGEIGPLGQSFSIPGQWLGPMGLFTAILVAIISTRIFVAITRK
GLIIKMPENVPEFISKSFSSLIPGIAILTLFTIISAVITSVGYGSIHEIIYKLIQVPLTSLGSGIWSLIFVAVVAQLLWF
FGLHGHAITLGIVAPIWFAMDAQQLAAYAAGVDLPNITGFAFFMTYGAAGDLLPLAIMLAFFAKSARYKTLGKIALPPAI
FTIGEPMAYGVPLVMNFTLAIPYIFINGIMLGIAWYLTVIGVLPRVAGVSTPAGMPIIISGFMQGSWKIAAFQFIGLFAR
FAGWYFFFKTADLVACREENQTDTI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=427, Percent_Identity=29.5081967213115, Blast_Score=154, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 46485; Mature: 46354

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHTNIVQEKALQLMQSIGQNTYLKSIMSGMMLILPVTIMSSVATLVKVFPFAPYQDFL
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LRHNLTRFFDIPITFTNNFLAVIVAFSVAYTLAKNFDVDGFMSGLISMISFFILTPYDLG
HHHCCHHHEECCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
EIGPLGQSFSIPGQWLGPMGLFTAILVAIISTRIFVAITRKGLIIKMPENVPEFISKSFS
CCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCHHHHHHHHHH
SLIPGIAILTLFTIISAVITSVGYGSIHEIIYKLIQVPLTSLGSGIWSLIFVAVVAQLLW
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFGLHGHAITLGIVAPIWFAMDAQQLAAYAAGVDLPNITGFAFFMTYGAAGDLLPLAIML
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
AFFAKSARYKTLGKIALPPAIFTIGEPMAYGVPLVMNFTLAIPYIFINGIMLGIAWYLTV
HHHHHCCCHHHHCCHHCCCHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVLPRVAGVSTPAGMPIIISGFMQGSWKIAAFQFIGLFARFAGWYFFFKTADLVACREE
HHHHHHHHCCCCCCCCHHHEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NQTDTI
CCCCCC
>Mature Secondary Structure 
SSHTNIVQEKALQLMQSIGQNTYLKSIMSGMMLILPVTIMSSVATLVKVFPFAPYQDFL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LRHNLTRFFDIPITFTNNFLAVIVAFSVAYTLAKNFDVDGFMSGLISMISFFILTPYDLG
HHHCCHHHEECCEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
EIGPLGQSFSIPGQWLGPMGLFTAILVAIISTRIFVAITRKGLIIKMPENVPEFISKSFS
CCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCHHHHHHHHHH
SLIPGIAILTLFTIISAVITSVGYGSIHEIIYKLIQVPLTSLGSGIWSLIFVAVVAQLLW
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFGLHGHAITLGIVAPIWFAMDAQQLAAYAAGVDLPNITGFAFFMTYGAAGDLLPLAIML
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
AFFAKSARYKTLGKIALPPAIFTIGEPMAYGVPLVMNFTLAIPYIFINGIMLGIAWYLTV
HHHHHCCCHHHHCCHHCCCHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVLPRVAGVSTPAGMPIIISGFMQGSWKIAAFQFIGLFARFAGWYFFFKTADLVACREE
HHHHHHHHCCCCCCCCHHHEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NQTDTI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407820 [H]