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The map label for this gene is 238894835

Identifier: 238894835

GI number: 238894835

Start: 2717504

End: 2718439

Strand: Direct

Name: 238894835

Synonym: KP1_2851

Alternate gene names: NA

Gene position: 2717504-2718439 (Clockwise)

Preceding gene: 238894834

Following gene: 238894836

Centisome position: 51.78

GC content: 58.87

Gene sequence:

>936_bases
ATGAAAAAGTCGCTTTTCGCCGGGGCAACCCTGACGGCACTGGTCAGCGGCCACGCGCTGGCCAATGAACCGCTGACGCT
GGTCCTGGACTGGTACATTAACCCCGACCATGCGCCGATTATGGTGGCCGAGCAGATCGGCGCCTTTAAGGCTCAGGGGC
TGGACGTCAAGATTGTCCCTCCCTCCGATCCCGCGCTGCCTCCGCGCATGGTGGCCGCCCGTCAAGCGGATCTGGCCATC
ACCTACCAGCCGCAGGTGCACTTTTTTGCTGACGAAGGGTTACCGCTGGTGCGTGTAGGGACACTGATTAATTCGCCGCT
GAATACGGTTATCGCCCTGGATAAGCAGATCAAAACCCCGGCAGATCTGCAAGGCAAGAAGGTGGGCTACTCGGTCAGCG
GCATTGAGCAGGCCACCCTGTCGACCATGGCGCAACACGCGGGGATCGATCCGGCCAGTATCAAACTGGTTAACGTCAAT
TTCCAGCTGACCAGCGCCCTGCTGGCGGGCCAGGTGGACGCGGTCATCGGCGGCTACCGTAATATAGAAGCGCAGGAGCT
GAAGCTGCAGGGCAAAACGCCGGTAGTGATGAACGTCGAAGATTACGGCGTGCCGGCCTATGACGAGCTGGTGATTGTCG
CCCATCGCGACGCGATTCATGAGGCCAAGATCCGTAAATTCCTCACCGCCCTGCAGGCCGGAGTGAGCTATCTGCGCGCC
CATCCGCAGGAGTGCTGGGAGGCGTTTGCCGCCGCCCACCCGGAGCTTAGGACCGAACTCAACCACCAGGCGTGGCTGCA
AACCGTGCCCCTGTTCGCCACCGATCCGGCGGCGCTGGATAAACCGCGCTACGAAGCTTATGAACAGTTTTTATATAACA
ATAAGTTGGTGAAAAAAGTCACACCTTTAACAAATTATGCGGTGGAACTGCATTGA

Upstream 100 bases:

>100_bases
AGTGCTACTGACCCTCCTGCTGTGGCTGGCAGTAGATACCCTGCTACACCGGCTGATCGACTGGTCACCGGAATAAAGAT
GAAGTAATAAAGGAAAACAG

Downstream 100 bases:

>100_bases
GTCTTGCTATCGCTGACGGAAGGCATTCCGTCAGCGCTTTAACGTAGCGGCAATAAAAATATAGAGACTTTCTCACTAAT
AATTACACTTTAAAGGGTTA

Product: NMT1/THI5 like domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKKSLFAGATLTALVSGHALANEPLTLVLDWYINPDHAPIMVAEQIGAFKAQGLDVKIVPPSDPALPPRMVAARQADLAI
TYQPQVHFFADEGLPLVRVGTLINSPLNTVIALDKQIKTPADLQGKKVGYSVSGIEQATLSTMAQHAGIDPASIKLVNVN
FQLTSALLAGQVDAVIGGYRNIEAQELKLQGKTPVVMNVEDYGVPAYDELVIVAHRDAIHEAKIRKFLTALQAGVSYLRA
HPQECWEAFAAAHPELRTELNHQAWLQTVPLFATDPAALDKPRYEAYEQFLYNNKLVKKVTPLTNYAVELH

Sequences:

>Translated_311_residues
MKKSLFAGATLTALVSGHALANEPLTLVLDWYINPDHAPIMVAEQIGAFKAQGLDVKIVPPSDPALPPRMVAARQADLAI
TYQPQVHFFADEGLPLVRVGTLINSPLNTVIALDKQIKTPADLQGKKVGYSVSGIEQATLSTMAQHAGIDPASIKLVNVN
FQLTSALLAGQVDAVIGGYRNIEAQELKLQGKTPVVMNVEDYGVPAYDELVIVAHRDAIHEAKIRKFLTALQAGVSYLRA
HPQECWEAFAAAHPELRTELNHQAWLQTVPLFATDPAALDKPRYEAYEQFLYNNKLVKKVTPLTNYAVELH
>Mature_311_residues
MKKSLFAGATLTALVSGHALANEPLTLVLDWYINPDHAPIMVAEQIGAFKAQGLDVKIVPPSDPALPPRMVAARQADLAI
TYQPQVHFFADEGLPLVRVGTLINSPLNTVIALDKQIKTPADLQGKKVGYSVSGIEQATLSTMAQHAGIDPASIKLVNVN
FQLTSALLAGQVDAVIGGYRNIEAQELKLQGKTPVVMNVEDYGVPAYDELVIVAHRDAIHEAKIRKFLTALQAGVSYLRA
HPQECWEAFAAAHPELRTELNHQAWLQTVPLFATDPAALDKPRYEAYEQFLYNNKLVKKVTPLTNYAVELH

Specific function: Probably involved in thiamine biosynthesis [H]

COG id: COG0715

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NMT1 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319957, Length=270, Percent_Identity=24.4444444444444, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321050, Length=270, Percent_Identity=24.4444444444444, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323997, Length=270, Percent_Identity=24.4444444444444, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322616, Length=270, Percent_Identity=24.0740740740741, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 33967; Mature: 33967

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSLFAGATLTALVSGHALANEPLTLVLDWYINPDHAPIMVAEQIGAFKAQGLDVKIVP
CCCCHHCCHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEEEHHHCCHHHCCCEEEEEC
PSDPALPPRMVAARQADLAITYQPQVHFFADEGLPLVRVGTLINSPLNTVIALDKQIKTP
CCCCCCCHHHHHHCCCCEEEEECCCEEEEECCCCCEEEEHHHHCCCHHHHEEECHHCCCC
ADLQGKKVGYSVSGIEQATLSTMAQHAGIDPASIKLVNVNFQLTSALLAGQVDAVIGGYR
CCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHCCHHHHHCCCC
NIEAQELKLQGKTPVVMNVEDYGVPAYDELVIVAHRDAIHEAKIRKFLTALQAGVSYLRA
CCCHHHEEECCCCCEEEEEHHCCCCCHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHC
HPQECWEAFAAAHPELRTELNHQAWLQTVPLFATDPAALDKPRYEAYEQFLYNNKLVKKV
CHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCEECCCHHCCCCHHHHHHHHHHCCHHHHHH
TPLTNYAVELH
CCCCCEEEEEC
>Mature Secondary Structure
MKKSLFAGATLTALVSGHALANEPLTLVLDWYINPDHAPIMVAEQIGAFKAQGLDVKIVP
CCCCHHCCHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEEEHHHCCHHHCCCEEEEEC
PSDPALPPRMVAARQADLAITYQPQVHFFADEGLPLVRVGTLINSPLNTVIALDKQIKTP
CCCCCCCHHHHHHCCCCEEEEECCCEEEEECCCCCEEEEHHHHCCCHHHHEEECHHCCCC
ADLQGKKVGYSVSGIEQATLSTMAQHAGIDPASIKLVNVNFQLTSALLAGQVDAVIGGYR
CCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHCCHHHHHCCCC
NIEAQELKLQGKTPVVMNVEDYGVPAYDELVIVAHRDAIHEAKIRKFLTALQAGVSYLRA
CCCHHHEEECCCCCEEEEEHHCCCCCHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHC
HPQECWEAFAAAHPELRTELNHQAWLQTVPLFATDPAALDKPRYEAYEQFLYNNKLVKKV
CHHHHHHHHHHCCCHHHHHCCHHHHHHCCCCEECCCHHCCCCHHHHHHHHHHCCHHHHHH
TPLTNYAVELH
CCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]