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The map label for this gene is dat [H]

Identifier: 238894836

GI number: 238894836

Start: 2718677

End: 2720131

Strand: Direct

Name: dat [H]

Synonym: KP1_2852

Alternate gene names: 238894836

Gene position: 2718677-2720131 (Clockwise)

Preceding gene: 238894835

Following gene: 238894837

Centisome position: 51.8

GC content: 59.38

Gene sequence:

>1455_bases
ATGCCAATTCAATTTCTTACACCAATTATTCAACCAGCGTTCAACCGCAATGCTGGTTGTGGGAGTGATATGATGACGGA
TAAAGTCCGTATTGATACTTTACGTGCCGATTTATTAGACGCAAACAACGAAACCTTTTTGGCCCGTCAGGCCGAATTCG
AATCGAATGTCAGGAGTTACCCGCGTAAGCTGCCGCTGGCTATCACTAAAGCCGAAGGCGTGTGGCTGACGGATGCGGAT
AACAAACAGTACCTGGACTGCCTCGCGGGCGCCGGTACTCTCGCTCTGGGCCACAACCACCCTGATGTATTGCAGAGCAT
CCAAAGTGTCATTACCAGCGGCTTGCCGTTACATACTCTCGATCTTACCACCCCGTTAAAAGATCGCTTCTCCGAATACC
TGCTCTCTTGCCTGCCGGGCGAAGGGAAAGAATATTGCCTGCAGTTCACCGGCCCGTCCGGCGCTGACGCCGTGGAAGCC
GCGCTGAAGCTGGCGAAAAAATACACCGGTCGTACCGCGGTGATCAGCTTCTCCGGCGGCTATCACGGGATGACCCACGG
CGCGCTGTCCGTCACCGGCAACCTGTCGCCGAAAGCGGCGGTTAACGGCATGATGCCGGAAGTCCAGTTCATGCCTTACC
CGCACCTGTATCGTTGCCCGCTGGGCATCGGCGGCGAAGCCGGCGTGAAGGCCCTGACCTACTACTTCGAAAACCTGATC
AACGACGTGGAGAGCGGCGTCCGTAAACCGGCGGCGGTGATCCTTGAAGCCGTGCAGGGCGAAGGCGGTGTGAACCCGGC
GCCGGTCGAGTGGCTGCAGCGCATCCGCAAAGTGACCGAAGAGCACGGCATTCTGCTGATCGTCGATGAAGTGCAGGCCG
GCTTTGCCCGTACCGGTAAATTCTTCGCCTTCGAGCACGCCGGTATTCAGCCGGACATCATCGTGATGTCGAAAGCGGTT
GGCGGCGGGCTGCCGCTGGCGGTGCTGGGCATTAAAAAGCAGTTCGACGCCTGGGAACCGGGTCACCACACCGGCACCTT
CCGCGGTAACCAGCTGGCGATGGCCACCGGCCTGACCACCCTGCGTCATCTGCGCGACAACAAGATCGCCGACAAAGTCG
CCGCCCAGGGCGAGTGGCTGAAAGGTAAACTGGCCGAGCTGCAGAAACGCTACCCGGTGATTGGCCACGTTCGCGGTCTC
GGTCTGATGATCGGTATCGAAATCGTCAAGCCGAACGAAGCGCAGGATCACATGGGCTGCTACCCGGCTGACGGCGAACT
CTCTGCCCTGCTGCAGAAGAAATGCTTCGAAGCGGGCCTGATCCTCGAGCGTGGCGGTCGTCACGGCTGCGTGCTGCGCC
TGCTGCCGTCCCTGCTGATCAGCGACGCGGAGCTGGACGTGTTCCTCGACAAATTTGAACAGGCCCTGCTGGCCGCCGGC
GTAAAACCGGTCTGA

Upstream 100 bases:

>100_bases
TACGTTAATTTTGCCCCTGGTAAGAATAACGTCAAAATAGCGCAATCAATAAAACGTTGAATGCGGATTTAAAAAGCCAT
ATATTGTGCGCGCTTTATGA

Downstream 100 bases:

>100_bases
GTGGAGTAAGTGACCGCCATGTCCACATTGAATCCGATTCTTGCTGGTTCAGCGCAGAGCGTTGAAGCCTATCAGCAGGT
TATCGAGCAGACCAGCCAGG

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MPIQFLTPIIQPAFNRNAGCGSDMMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDAD
NKQYLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEA
ALKLAKKYTGRTAVISFSGGYHGMTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLI
NDVESGVRKPAAVILEAVQGEGGVNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAV
GGGLPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGL
GLMIGIEIVKPNEAQDHMGCYPADGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAG
VKPV

Sequences:

>Translated_484_residues
MPIQFLTPIIQPAFNRNAGCGSDMMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDAD
NKQYLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEA
ALKLAKKYTGRTAVISFSGGYHGMTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLI
NDVESGVRKPAAVILEAVQGEGGVNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAV
GGGLPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGL
GLMIGIEIVKPNEAQDHMGCYPADGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAG
VKPV
>Mature_483_residues
PIQFLTPIIQPAFNRNAGCGSDMMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDADN
KQYLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEAA
LKLAKKYTGRTAVISFSGGYHGMTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLIN
DVESGVRKPAAVILEAVQGEGGVNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAVG
GGLPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGLG
LMIGIEIVKPNEAQDHMGCYPADGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAGV
KPV

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=29.4520547945205, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=29.6728971962617, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI24119277, Length=453, Percent_Identity=28.0353200883002, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=28.7735849056604, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI226442709, Length=397, Percent_Identity=29.7229219143577, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4557809, Length=441, Percent_Identity=24.7165532879819, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI284507298, Length=338, Percent_Identity=26.0355029585799, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI188536080, Length=449, Percent_Identity=25.3897550111359, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679950, Length=449, Percent_Identity=25.3897550111359, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679946, Length=449, Percent_Identity=25.3897550111359, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1787560, Length=411, Percent_Identity=35.2798053527981, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=35.4761904761905, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI145693181, Length=414, Percent_Identity=31.8840579710145, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1788044, Length=419, Percent_Identity=29.3556085918854, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1789759, Length=420, Percent_Identity=30, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=30.5825242718447, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1786349, Length=364, Percent_Identity=28.2967032967033, Blast_Score=123, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=31.264367816092, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=459, Percent_Identity=27.8867102396514, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=28.433734939759, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25144274, Length=329, Percent_Identity=28.8753799392097, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=446, Percent_Identity=25.3363228699552, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=439, Percent_Identity=30.751708428246, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6323470, Length=431, Percent_Identity=28.538283062645, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321456, Length=440, Percent_Identity=25.6818181818182, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=489, Percent_Identity=23.3128834355828, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161085790, Length=449, Percent_Identity=30.9576837416481, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI28574759, Length=449, Percent_Identity=31.1804008908686, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357415, Length=427, Percent_Identity=26.6978922716628, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21356575, Length=461, Percent_Identity=26.6811279826464, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281366494, Length=445, Percent_Identity=22.4719101123595, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667139, Length=445, Percent_Identity=22.4719101123595, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667143, Length=445, Percent_Identity=22.4719101123595, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 52369; Mature: 52238

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQFLTPIIQPAFNRNAGCGSDMMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSY
CCHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
PRKLPLAITKAEGVWLTDADNKQYLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTL
CCCCCEEEEECCCEEEECCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
DLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEAALKLAKKYTGRTAVISFSGG
ECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCC
YHGMTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLI
CCCCCCCEEEEECCCCCHHHHCCCCCCCEECCCCCCEECCCCCCCHHHHHHHHHHHHHHH
NDVESGVRKPAAVILEAVQGEGGVNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGK
HHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCC
FFAFEHAGIQPDIIVMSKAVGGGLPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTT
EEEEECCCCCCCEEEEEECCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCEEEHHHHHHH
LRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGLGLMIGIEIVKPNEAQDHMGC
HHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCEEEEEEEEECCCCCHHHCCC
YPADGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAG
CCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
VKPV
CCCC
>Mature Secondary Structure 
PIQFLTPIIQPAFNRNAGCGSDMMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSY
CHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHC
PRKLPLAITKAEGVWLTDADNKQYLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTL
CCCCCEEEEECCCEEEECCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
DLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEAALKLAKKYTGRTAVISFSGG
ECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCC
YHGMTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLI
CCCCCCCEEEEECCCCCHHHHCCCCCCCEECCCCCCEECCCCCCCHHHHHHHHHHHHHHH
NDVESGVRKPAAVILEAVQGEGGVNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGK
HHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCC
FFAFEHAGIQPDIIVMSKAVGGGLPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTT
EEEEECCCCCCCEEEEEECCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCEEEHHHHHHH
LRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGLGLMIGIEIVKPNEAQDHMGC
HHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCEEEEEEEEECCCCCHHHCCC
YPADGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAG
CCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
VKPV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9260954 [H]