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The map label for this gene is oxlT [H]

Identifier: 238894786

GI number: 238894786

Start: 2666711

End: 2668132

Strand: Direct

Name: oxlT [H]

Synonym: KP1_2796

Alternate gene names: 238894786

Gene position: 2666711-2668132 (Clockwise)

Preceding gene: 238894785

Following gene: 238894788

Centisome position: 50.81

GC content: 59.07

Gene sequence:

>1422_bases
ATGGCACGTTTAATGCTCTTCGCTTGTATACCGCAATGTGGACAAGAACGTATGCCATATGGCCACAACAGGTCGCCAGT
CTGCGGTCGCAACCTTCCCCTTTCTGTGAGGCATCCAGGGTGGATGCGTTTCACGGAAGCCTGCTTACTGAAAACGGAGA
ACAACATGACGACACTCAGTGAACCGTTGGTTACCCCGAAATATGGCAAATGGCGCCAGCTGGTGCTGGGTTTGATCTGT
ATGGCCGCCATTTCCAGTCCGCAATATGTCTGGACGCTGTTGACAAAACCCCTGGCCGCTAAACTGGGCGTGGGTTTGCC
AGAATTGCAGGTCACCTTCTCGCTACTGATCATCCTGCAGACCTTCTTTTCCCCTTTTCAGGGGCGATTAGTGGAAAAAT
TTGGCCCACGGCGGCTGATCGCTATTGGCACGGTGATGGCGGGCATGAGCTGGGTGCTTTCCGCGCAGGTGAATGGCCTG
GCAACGCTCTGGCTGGTTTATGGCTGCATGGGCGGCCTCGGGACCGGGATCGTCTACATCGGCGTTGTCGGCCTGATGGT
CAAATGGTTCCCACAGCAGCGGGGATTTGCCGCCGGCGCGGTGGCGGCGGGCTACGGGATGGGGGCCATCATAACCACCT
TCCCCATCTCCCTGTCGCTGACCACTAACGGCCTTGAACACACGATGACGACTTTCGGGATCCTTTTCGCCCTCGTCGGC
TTCCTCGCCAGTCAGGGGCTGAAGCTGCCGCCGCCCGCTGTCTCCCAGCCCGTCAGTCAGACGGTGGTGCAGAGCAGCAG
ATCGTTTACTTCCCGGGAAATGCTGCGCCAGCCGCTGTTCTGGCTGATGTTCGCCATGATGGCGATGATGTCGACTTCCG
GGCTGATGGTCACTTCGCAGATGGCGGTGTTCGCCGAGGATTTCGGCATTAGCCAGGCGGTGGTGTTTGGCATGGCGGCG
CTGCCGCTGGCGTTAACGATAGACCGCTTTACCAACGGCTTAACCCGGCCGCTGTTTGGGTTTATTTCCGACCGCTTCGG
CCGCGAGCAAACCATGTTTATCGCCTTTGCGCTGGAGGGGGTAGCGATGATGCTCTGGCTGGCGTGCCGGGAAGATCCGC
TGCTGTTTGTCCTGCTCTCCGGGGTGGTGTTCTTTGGCTGGGGGGAGATCTTCTCGCTCTTCCCGTCGACGCTCACCGAT
ACGTTCGGCAGCGAGCATGCCGCCAGCAACTATGGCTGGCTGTATATTTCGCAGGGCATCGGGTCAATCTTTGGCGGTCC
GCTGGCGGCACTGCTCTATCAGCACACTCACGGCTGGCATGTGGTCTTCAGCTGCGCGATTGGCCTTGATTTTGTCACCG
CCGCCCTCGCGCTGTGGGTGCTAAAACCGTGGCGCGCGCGCTTTATCCGCCAGCATAGCTAA

Upstream 100 bases:

>100_bases
ATTCATTTGCACCGCCCTGGTGCCGCACATTCACCATGCCGCCCCCCCGTCAGACATGCCCTCATTACATTAACCAGTTG
AATATAAAAAATTATTTTAT

Downstream 100 bases:

>100_bases
TCGTCCGCCGGGCAGAAGTGACGGCTCGCCCGTCACTTCACTGATATTCGCTACGCAACAGCGCGTACAGGTACTCATCG
CCCCACTCGCCTTTAAAAAA

Product: putative permease of the major facilitator superfamily

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MARLMLFACIPQCGQERMPYGHNRSPVCGRNLPLSVRHPGWMRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLIC
MAAISSPQYVWTLLTKPLAAKLGVGLPELQVTFSLLIILQTFFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGL
ATLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAVAAGYGMGAIITTFPISLSLTTNGLEHTMTTFGILFALVG
FLASQGLKLPPPAVSQPVSQTVVQSSRSFTSREMLRQPLFWLMFAMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAA
LPLALTIDRFTNGLTRPLFGFISDRFGREQTMFIAFALEGVAMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTD
TFGSEHAASNYGWLYISQGIGSIFGGPLAALLYQHTHGWHVVFSCAIGLDFVTAALALWVLKPWRARFIRQHS

Sequences:

>Translated_473_residues
MARLMLFACIPQCGQERMPYGHNRSPVCGRNLPLSVRHPGWMRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLIC
MAAISSPQYVWTLLTKPLAAKLGVGLPELQVTFSLLIILQTFFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGL
ATLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAVAAGYGMGAIITTFPISLSLTTNGLEHTMTTFGILFALVG
FLASQGLKLPPPAVSQPVSQTVVQSSRSFTSREMLRQPLFWLMFAMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAA
LPLALTIDRFTNGLTRPLFGFISDRFGREQTMFIAFALEGVAMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTD
TFGSEHAASNYGWLYISQGIGSIFGGPLAALLYQHTHGWHVVFSCAIGLDFVTAALALWVLKPWRARFIRQHS
>Mature_472_residues
ARLMLFACIPQCGQERMPYGHNRSPVCGRNLPLSVRHPGWMRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLICM
AAISSPQYVWTLLTKPLAAKLGVGLPELQVTFSLLIILQTFFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLA
TLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAVAAGYGMGAIITTFPISLSLTTNGLEHTMTTFGILFALVGF
LASQGLKLPPPAVSQPVSQTVVQSSRSFTSREMLRQPLFWLMFAMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAAL
PLALTIDRFTNGLTRPLFGFISDRFGREQTMFIAFALEGVAMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTDT
FGSEHAASNYGWLYISQGIGSIFGGPLAALLYQHTHGWHVVFSCAIGLDFVTAALALWVLKPWRARFIRQHS

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=374, Percent_Identity=29.144385026738, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI193209150, Length=335, Percent_Identity=25.6716417910448, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51856; Mature: 51725

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLMLFACIPQCGQERMPYGHNRSPVCGRNLPLSVRHPGWMRFTEACLLKTENNMTTLS
CCHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCCCCC
EPLVTPKYGKWRQLVLGLICMAAISSPQYVWTLLTKPLAAKLGVGLPELQVTFSLLIILQ
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TFFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLATLWLVYGCMGGLGTGIVYI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVGLMVKWFPQQRGFAAGAVAAGYGMGAIITTFPISLSLTTNGLEHTMTTFGILFALVG
HHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHH
FLASQGLKLPPPAVSQPVSQTVVQSSRSFTSREMLRQPLFWLMFAMMAMMSTSGLMVTSQ
HHHHCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHCCCCCEEHHH
MAVFAEDFGISQAVVFGMAALPLALTIDRFTNGLTRPLFGFISDRFGREQTMFIAFALEG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VAMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTDTFGSEHAASNYGWLYISQGI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCH
GSIFGGPLAALLYQHTHGWHVVFSCAIGLDFVTAALALWVLKPWRARFIRQHS
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARLMLFACIPQCGQERMPYGHNRSPVCGRNLPLSVRHPGWMRFTEACLLKTENNMTTLS
CHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCCCCC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HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]