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The map label for this gene is hrsA [H]

Identifier: 238894780

GI number: 238894780

Start: 2661721

End: 2662191

Strand: Reverse

Name: hrsA [H]

Synonym: KP1_2790

Alternate gene names: 238894780

Gene position: 2662191-2661721 (Counterclockwise)

Preceding gene: 238894781

Following gene: 238894779

Centisome position: 50.72

GC content: 45.01

Gene sequence:

>471_bases
ATGGATATTTCGACAGTGCTTAATGTTAAAAACATCAAGTTAAATATGACCGCCAGAACCAAAGAAGAGGTGATAGAAGA
ACTCACCGATTTACTTATCCAGGATGGCGCCGTCACCAATAAGGAAGACTTTATTCGTGATGTCTGGTTACGCGAGGAGC
TAGGCTCTACCGGCTTTGAAAACCATATCGCTATTCCACATGGTAAATCTTCCGGTGTTTCCCGTACCGCATTAGCCATC
GGACGCACGCAACATGCCATTCCCTGGGAGACCATGGATGGCAGCGATGTCCGCTGTGTTATTTTATTTGCGGTTTGCCT
GGTGGATCAAAATGCCACCCATATTCGCCTGTTGGCACAAGTGTCTGGGTCACTGGCGGATGAAGACATTATCGCTAAAT
TACTTGTTGAATCTGATCCACATAAAATCATTGCGCTTTTCAATTCAGAAACTGAAAACGCCGATGCTTAA

Upstream 100 bases:

>100_bases
GAACCACAGTGTGTATTTGAATAAGCCTTAAAAGATCTGCATCACGCCAGCGATGCTGGTTTGTTATTTAACGACCACTC
TATATGAATGCGGGTGAATC

Downstream 100 bases:

>100_bases
TACCAACTTGCTAATATCGATTTGTAATTTATTAAATTAATTAACGGAGAAACATTATGAATATTGTCGGCGTTACCGCC
TGCACGGTGGGGATTGCACA

Product: fructose-mannitol-specific PTS family enzyme IIA component

Products: NA

Alternate protein names: Putative PTS system EIIABC component; Phosphotransferase enzyme IIA component; PTS system EIIA component; Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MDISTVLNVKNIKLNMTARTKEEVIEELTDLLIQDGAVTNKEDFIRDVWLREELGSTGFENHIAIPHGKSSGVSRTALAI
GRTQHAIPWETMDGSDVRCVILFAVCLVDQNATHIRLLAQVSGSLADEDIIAKLLVESDPHKIIALFNSETENADA

Sequences:

>Translated_156_residues
MDISTVLNVKNIKLNMTARTKEEVIEELTDLLIQDGAVTNKEDFIRDVWLREELGSTGFENHIAIPHGKSSGVSRTALAI
GRTQHAIPWETMDGSDVRCVILFAVCLVDQNATHIRLLAQVSGSLADEDIIAKLLVESDPHKIIALFNSETENADA
>Mature_156_residues
MDISTVLNVKNIKLNMTARTKEEVIEELTDLLIQDGAVTNKEDFIRDVWLREELGSTGFENHIAIPHGKSSGVSRTALAI
GRTQHAIPWETMDGSDVRCVILFAVCLVDQNATHIRLLAQVSGSLADEDIIAKLLVESDPHKIIALFNSETENADA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=151, Percent_Identity=29.8013245033113, Blast_Score=90, Evalue=8e-20,
Organism=Escherichia coli, GI2367327, Length=142, Percent_Identity=28.8732394366197, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1788726, Length=149, Percent_Identity=26.8456375838926, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 17164; Mature: 17164

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISTVLNVKNIKLNMTARTKEEVIEELTDLLIQDGAVTNKEDFIRDVWLREELGSTGFE
CCCHHEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
NHIAIPHGKSSGVSRTALAIGRTQHAIPWETMDGSDVRCVILFAVCLVDQNATHIRLLAQ
CCEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEHEEH
VSGSLADEDIIAKLLVESDPHKIIALFNSETENADA
HHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MDISTVLNVKNIKLNMTARTKEEVIEELTDLLIQDGAVTNKEDFIRDVWLREELGSTGFE
CCCHHEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
NHIAIPHGKSSGVSRTALAIGRTQHAIPWETMDGSDVRCVILFAVCLVDQNATHIRLLAQ
CCEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEEHEEH
VSGSLADEDIIAKLLVESDPHKIIALFNSETENADA
HHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9063979; 9278503; 8905232 [H]