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The map label for this gene is alkR [H]

Identifier: 238894698

GI number: 238894698

Start: 2581593

End: 2582537

Strand: Reverse

Name: alkR [H]

Synonym: KP1_2704

Alternate gene names: 238894698

Gene position: 2582537-2581593 (Counterclockwise)

Preceding gene: 238894700

Following gene: 238894694

Centisome position: 49.21

GC content: 66.35

Gene sequence:

>945_bases
ATGAGCCAGCCTGCCATCGATCTGACCAGCGAACTGTTGCGCGGTATGCGCCTCTCCGGCGTTAACTACCGGCGCATCGA
AACCGCACGCCCGTTCGGCGTCGGCTTTAGCGCCGTGGCGGGTAAAGCCCAGTTCCATTTCATCAGCCGCGGGCCGGTGC
TGCTGCGCATGGCCAGCGGAGAACAGTTCACCCTCGAGAGCGGCGATGCGCTGTTTATTCCCAACGGCGACGGGCACGCC
CTGCTCTCGGATCCGCAGGCCACGGTGGTCAACGTGGCGCAGCTGCCCAGCGAAACGGTGTGCAGCACGGTAAGTTGTAT
CAACGCTGGCGACCAGCCTGACTGCCCGGAGCGCGCCGTCATTTTCAGCGGTTGTATGGACTTTGAGCTCGGCGGCATGC
AGCCGCTGGTCAAGGCCATGCCCGAGGTGATGCGGGTCAGCAGCCTGCTAAACACCTGGCCGGAGATCCAGCCGCTGTTG
GCGGCGATGGAGCGGGAATCGCTCACCCGCCAGGCAGGCTATGCCGGGATCCTCGCCCGGCTGGCGGACGTGGTGGCCGC
GCTGATTGTCCGCGGCTGGGTAGCGTGCGGGTGCGGCAACGCCACTGGCTGGGTACAGGTCCTGCGCGATCCCCGGCTGG
CGAAAGCGATCTACGCCATGCATCAGCGCCCGGGGGTCAACTGGAAAGTGGAAGATCTGGCGCGGGAGGCGGGTCTTTCA
CGCTCGCTGTTCGCGGAACGTTTTCTCGCCGCCACCGGCACCACCCCCGCCCGCTATCTCACCGAGCTGCGTATGCGGCT
GGCGGTGCAGTACATCACCCATGAAGGCCAGGCGCTGGAAAAAGTCGCCTTCAGCCTCGGGTATCAGTCGCTGGCGGCCT
TCAGCCGGGCTTTCAAACGCATCACCGGCCAGCCGCCGGGGGCCCTGCGCGCCACGGCACGCTAG

Upstream 100 bases:

>100_bases
ACTCTCCAGGTTTATTAACATCCTGGTCATCTTAGGGCCTTACTTTCGGACGATATATGATGCATACTCTTCAGTTATTG
ATTATTCGTCCGGAATTACC

Downstream 100 bases:

>100_bases
AGTCAGCCTTTATGTAAAGCGATACACGCCGTTGCCGACACGAAAGCGCTGCCCCTTAAGCGCCGGGTTGGCGACGCGGA
ACACCAGTTCGGTCAGCTGG

Product: putative AraC-type regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSQPAIDLTSELLRGMRLSGVNYRRIETARPFGVGFSAVAGKAQFHFISRGPVLLRMASGEQFTLESGDALFIPNGDGHA
LLSDPQATVVNVAQLPSETVCSTVSCINAGDQPDCPERAVIFSGCMDFELGGMQPLVKAMPEVMRVSSLLNTWPEIQPLL
AAMERESLTRQAGYAGILARLADVVAALIVRGWVACGCGNATGWVQVLRDPRLAKAIYAMHQRPGVNWKVEDLAREAGLS
RSLFAERFLAATGTTPARYLTELRMRLAVQYITHEGQALEKVAFSLGYQSLAAFSRAFKRITGQPPGALRATAR

Sequences:

>Translated_314_residues
MSQPAIDLTSELLRGMRLSGVNYRRIETARPFGVGFSAVAGKAQFHFISRGPVLLRMASGEQFTLESGDALFIPNGDGHA
LLSDPQATVVNVAQLPSETVCSTVSCINAGDQPDCPERAVIFSGCMDFELGGMQPLVKAMPEVMRVSSLLNTWPEIQPLL
AAMERESLTRQAGYAGILARLADVVAALIVRGWVACGCGNATGWVQVLRDPRLAKAIYAMHQRPGVNWKVEDLAREAGLS
RSLFAERFLAATGTTPARYLTELRMRLAVQYITHEGQALEKVAFSLGYQSLAAFSRAFKRITGQPPGALRATAR
>Mature_313_residues
SQPAIDLTSELLRGMRLSGVNYRRIETARPFGVGFSAVAGKAQFHFISRGPVLLRMASGEQFTLESGDALFIPNGDGHAL
LSDPQATVVNVAQLPSETVCSTVSCINAGDQPDCPERAVIFSGCMDFELGGMQPLVKAMPEVMRVSSLLNTWPEIQPLLA
AMERESLTRQAGYAGILARLADVVAALIVRGWVACGCGNATGWVQVLRDPRLAKAIYAMHQRPGVNWKVEDLAREAGLSR
SLFAERFLAATGTTPARYLTELRMRLAVQYITHEGQALEKVAFSLGYQSLAAFSRAFKRITGQPPGALRATAR

Specific function: This protein activates the expression of the alkane 1- monooxygenase AlkM [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786496, Length=286, Percent_Identity=26.2237762237762, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082197, Length=95, Percent_Identity=35.7894736842105, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33982; Mature: 33850

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPAIDLTSELLRGMRLSGVNYRRIETARPFGVGFSAVAGKAQFHFISRGPVLLRMASG
CCCCHHHHHHHHHHCHHHCCCCEEEECCCCCCCCCHHHHCCCCEEEEEECCCEEEEEECC
EQFTLESGDALFIPNGDGHALLSDPQATVVNVAQLPSETVCSTVSCINAGDQPDCPERAV
CEEEEECCCEEEEECCCCCEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHH
IFSGCMDFELGGMQPLVKAMPEVMRVSSLLNTWPEIQPLLAAMERESLTRQAGYAGILAR
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADVVAALIVRGWVACGCGNATGWVQVLRDPRLAKAIYAMHQRPGVNWKVEDLAREAGLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCH
RSLFAERFLAATGTTPARYLTELRMRLAVQYITHEGQALEKVAFSLGYQSLAAFSRAFKR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ITGQPPGALRATAR
HCCCCCCCCCCCCC
>Mature Secondary Structure 
SQPAIDLTSELLRGMRLSGVNYRRIETARPFGVGFSAVAGKAQFHFISRGPVLLRMASG
CCCHHHHHHHHHHCHHHCCCCEEEECCCCCCCCCHHHHCCCCEEEEEECCCEEEEEECC
EQFTLESGDALFIPNGDGHALLSDPQATVVNVAQLPSETVCSTVSCINAGDQPDCPERAV
CEEEEECCCEEEEECCCCCEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHH
IFSGCMDFELGGMQPLVKAMPEVMRVSSLLNTWPEIQPLLAAMERESLTRQAGYAGILAR
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADVVAALIVRGWVACGCGNATGWVQVLRDPRLAKAIYAMHQRPGVNWKVEDLAREAGLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCH
RSLFAERFLAATGTTPARYLTELRMRLAVQYITHEGQALEKVAFSLGYQSLAAFSRAFKR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ITGQPPGALRATAR
HCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9546151 [H]