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The map label for this gene is ynfE [H]

Identifier: 238894602

GI number: 238894602

Start: 2496873

End: 2499308

Strand: Reverse

Name: ynfE [H]

Synonym: KP1_2603

Alternate gene names: 238894602

Gene position: 2499308-2496873 (Counterclockwise)

Preceding gene: 238894603

Following gene: 238894601

Centisome position: 47.62

GC content: 59.89

Gene sequence:

>2436_bases
ATGTCGAATCAGGAATCTCCCGGCGGCGTCAGCCGACGCGCGCTACTAAAATCTACAGCCCTCGGCTCCCTGGCGCTGGC
CGCCGGCGGGCTGACCCTGCCCTTTACGCTGCGCCGCGCCGCGGCGGCGGTACAACAGGCTACCGGCGACAACACCCGCA
TTGTCTGGGGCGCCTGCTCGGTTAACTGCGGCAGCCGCTGCGCCCTGCGGCTGCACGTGCGTGATGATGAAGTGGTTTAC
GTCGAAACGGATAACACCGGCGACGACCGCTACGGCGACCATCAGGTCCGCGCCTGCCTGCGCGGGCGTTCGATTCGCCG
GCGCATCAATCATCCGGATCGCCTTAACTATCCCATGAAGCGCGTCGGCAAGCGCGGAGAAGGCAAATTTGTCCGCATCA
GCTGGCAGGAGGCGCTGGATACCCTCGCCGACCGCCTGAAGAGCGTGGTAGCACAGTATGGCAACGAAGCCGTATACATT
AACTACTCTTCAGGGATCGTCGGCGGCAACATCACCCGTTCGTCGCCTTCCGCGTCGCCGGTGGCGCGTTTAATGAACTG
CTACGGCGGCTCGCTTAACCAGTACGGTACCTACAGTACTGCGCAGATTGCCTGCGCCATGCCCTACACCTACGGCAGTA
ACGACGGCAACAGCACCTCGGATATTGAAAACAGCAAGCTGGTGGTGATGTTCGGCAACAATCCGGCGGAGACCCGGATG
AGCGGCGGCGGCATTACCTGGTATCTGGAGCAGGCCCGCGAGCGCTCTAACGCGCGAATGATCGTCATCGATCCGCGCTA
CACCGATACCGCCGCCGGTCGGGAAGATGAGTGGATCCCCATTCGCCCCGGCACCGACGCCGCGCTGGTGGCCGGTATCG
CCTGGGTGTTGATTAACGAAGATCTGGTGGACCAGCCTTTCCTTGATAAATACTGCGTTGGCTACGACGAGAAAACGCTC
CCGGCCGGGGCGCCGGCGAATGGTCATTACAAAGCCTATATCCTCGGCGAGGGCGACGACGGGATCGCTAAAACGCCGCA
GTGGGCCTCGCGTTTAACCGGTATCCCCACCGATCGCATCATTAAGCTGGCGCGCGAAATCGGCATGAGCAAGCCGGCCT
ACATTTGCCAGGGCTGGGGGCCCCAGCGCCAGGCCAACGGCGAACTCACCGCCCGGGCGATCGCCATGCTGCCGATCTTA
ACCGGCAACGTCGGCATCAACGGCGGCAATAGCGGCGCCCGCGAATCAACCTACACCATCACCATTGAGCGCCTGCCGGT
GCTGGAAAACCCGGTGAAGACCGCCATCTCCTGCTTTACCTGGACCGACGCCATCGCGCGCGGTCCAGAGATGACGGCCA
GCCGCGATGGCGTACGCGGAAAAGAGAAGCTGGATGTGCCGATCAAGTTCCTGTGGAACTACGCGGGCAACACCATCATC
AACCAGCACTCCGACATCAATAAGACCCACGAAATTCTGCAGGATGAAAGCAAGTGCGAAACCATTGTGGTTATCGACAA
CTTTATGACCTCGTCGGCGAAATACGCCGACCTGCTGCTGCCCGACCTGATGACCGTTGAGCAGGAGGATATCATTCCTA
ACGATTACGCCGGCAATATGGGCTATCTGATTTTTATTCAGCCCGCCACCTCAGCGAAGTTCGAACGCAAACCGATTTAC
TGGATCCTAAGCGAAGTGGCGAAACGACTCGGCGACGACGTGCATCAACGTTTTACCGAGGGACGTACCCAGGAACAGTG
GCTGCAGTATCTGTACGCCAAAATGGTGGCGAAAGATCCGGCGCTGCCGGCCTACGAGGATCTGAAGCGAATGGGCATCT
ACAAGCGCAAAGACCCGAACGGCCACTTCGTCGCCTATCGCGACTTCCGGCGCGATCCTGAAGCGCATCCGCTCAAAACC
CCGTCCGGCAAAATTGAAATCTACTCAAGCCGACTCGCAGAGATTGCCGCCCGCTGGCAGCTGGAGAAAGACGAAGTTAT
CAGCCCGCTGCCGGTCTACGCCTCCACATTTGAAGGCTGGGACGATCCGCTGCGCAGCCAGTATCCGCTGCAGCTGTTTG
GTTTCCACTATAAAGCGCGCACCCATTCCAGCTACGGCAACGTTGATGTATTACAAGCGGCCTGTCGCCAGGAAGTATGG
ATCAATCCGCTTGACGCGGAAAAACGCGGGATTAAAAACGGCGATATGGTGCGCGTTTTTAATCAGCGCGGCGAAGTCCG
TCTTCCGGCGAAAGTGACGCCACGCATCATGCCGGGGGTCTCGGCGATGGGCCAGGGCGCCTGGCACGACGCCAATATGA
CCGGAGATCGGATCGACCATGGCGCCTGCATGAATACCCTGACCACCCACCGCCCGTCGCCGCTGGCGAAGGGGAATCCA
CAGCATACCAACCTGGTCGATATCGAGAAGGTTTAA

Upstream 100 bases:

>100_bases
AAGGTCTACTGGCTACCCATAACGTATTATCGCTCACCCCTGCGTCTGTTAATGACGTGGCGGCCCTTCTCCGCACAGCA
TAACTATCATGGAGTGAGCA

Downstream 100 bases:

>100_bases
GGAGTAAACCATGAGCACGCAATATGGATTCTTTATCGACTCCGCTCGCTGTACCGGATGCAAAACCTGCGAGCTGGCCT
GTAAGGACTACAAGAACCTG

Product: putative dimethyl sulfoxide reductase major subunit

Products: NA

Alternate protein names: DMSO reductase [H]

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MSNQESPGGVSRRALLKSTALGSLALAAGGLTLPFTLRRAAAAVQQATGDNTRIVWGACSVNCGSRCALRLHVRDDEVVY
VETDNTGDDRYGDHQVRACLRGRSIRRRINHPDRLNYPMKRVGKRGEGKFVRISWQEALDTLADRLKSVVAQYGNEAVYI
NYSSGIVGGNITRSSPSASPVARLMNCYGGSLNQYGTYSTAQIACAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETRM
SGGGITWYLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINEDLVDQPFLDKYCVGYDEKTL
PAGAPANGHYKAYILGEGDDGIAKTPQWASRLTGIPTDRIIKLAREIGMSKPAYICQGWGPQRQANGELTARAIAMLPIL
TGNVGINGGNSGARESTYTITIERLPVLENPVKTAISCFTWTDAIARGPEMTASRDGVRGKEKLDVPIKFLWNYAGNTII
NQHSDINKTHEILQDESKCETIVVIDNFMTSSAKYADLLLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATSAKFERKPIY
WILSEVAKRLGDDVHQRFTEGRTQEQWLQYLYAKMVAKDPALPAYEDLKRMGIYKRKDPNGHFVAYRDFRRDPEAHPLKT
PSGKIEIYSSRLAEIAARWQLEKDEVISPLPVYASTFEGWDDPLRSQYPLQLFGFHYKARTHSSYGNVDVLQAACRQEVW
INPLDAEKRGIKNGDMVRVFNQRGEVRLPAKVTPRIMPGVSAMGQGAWHDANMTGDRIDHGACMNTLTTHRPSPLAKGNP
QHTNLVDIEKV

Sequences:

>Translated_811_residues
MSNQESPGGVSRRALLKSTALGSLALAAGGLTLPFTLRRAAAAVQQATGDNTRIVWGACSVNCGSRCALRLHVRDDEVVY
VETDNTGDDRYGDHQVRACLRGRSIRRRINHPDRLNYPMKRVGKRGEGKFVRISWQEALDTLADRLKSVVAQYGNEAVYI
NYSSGIVGGNITRSSPSASPVARLMNCYGGSLNQYGTYSTAQIACAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETRM
SGGGITWYLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINEDLVDQPFLDKYCVGYDEKTL
PAGAPANGHYKAYILGEGDDGIAKTPQWASRLTGIPTDRIIKLAREIGMSKPAYICQGWGPQRQANGELTARAIAMLPIL
TGNVGINGGNSGARESTYTITIERLPVLENPVKTAISCFTWTDAIARGPEMTASRDGVRGKEKLDVPIKFLWNYAGNTII
NQHSDINKTHEILQDESKCETIVVIDNFMTSSAKYADLLLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATSAKFERKPIY
WILSEVAKRLGDDVHQRFTEGRTQEQWLQYLYAKMVAKDPALPAYEDLKRMGIYKRKDPNGHFVAYRDFRRDPEAHPLKT
PSGKIEIYSSRLAEIAARWQLEKDEVISPLPVYASTFEGWDDPLRSQYPLQLFGFHYKARTHSSYGNVDVLQAACRQEVW
INPLDAEKRGIKNGDMVRVFNQRGEVRLPAKVTPRIMPGVSAMGQGAWHDANMTGDRIDHGACMNTLTTHRPSPLAKGNP
QHTNLVDIEKV
>Mature_810_residues
SNQESPGGVSRRALLKSTALGSLALAAGGLTLPFTLRRAAAAVQQATGDNTRIVWGACSVNCGSRCALRLHVRDDEVVYV
ETDNTGDDRYGDHQVRACLRGRSIRRRINHPDRLNYPMKRVGKRGEGKFVRISWQEALDTLADRLKSVVAQYGNEAVYIN
YSSGIVGGNITRSSPSASPVARLMNCYGGSLNQYGTYSTAQIACAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETRMS
GGGITWYLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINEDLVDQPFLDKYCVGYDEKTLP
AGAPANGHYKAYILGEGDDGIAKTPQWASRLTGIPTDRIIKLAREIGMSKPAYICQGWGPQRQANGELTARAIAMLPILT
GNVGINGGNSGARESTYTITIERLPVLENPVKTAISCFTWTDAIARGPEMTASRDGVRGKEKLDVPIKFLWNYAGNTIIN
QHSDINKTHEILQDESKCETIVVIDNFMTSSAKYADLLLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATSAKFERKPIYW
ILSEVAKRLGDDVHQRFTEGRTQEQWLQYLYAKMVAKDPALPAYEDLKRMGIYKRKDPNGHFVAYRDFRRDPEAHPLKTP
SGKIEIYSSRLAEIAARWQLEKDEVISPLPVYASTFEGWDDPLRSQYPLQLFGFHYKARTHSSYGNVDVLQAACRQEVWI
NPLDAEKRGIKNGDMVRVFNQRGEVRLPAKVTPRIMPGVSAMGQGAWHDANMTGDRIDHGACMNTLTTHRPSPLAKGNPQ
HTNLVDIEKV

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=811, Percent_Identity=85.8199753390875, Blast_Score=1484, Evalue=0.0,
Organism=Escherichia coli, GI171474008, Length=804, Percent_Identity=70.6467661691542, Blast_Score=1218, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=807, Percent_Identity=67.5340768277571, Blast_Score=1135, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=755, Percent_Identity=29.6688741721854, Blast_Score=280, Evalue=4e-76,
Organism=Escherichia coli, GI1787231, Length=763, Percent_Identity=30.1441677588467, Blast_Score=269, Evalue=6e-73,
Organism=Escherichia coli, GI87081994, Length=760, Percent_Identity=28.9473684210526, Blast_Score=252, Evalue=6e-68,
Organism=Escherichia coli, GI3868721, Length=781, Percent_Identity=24.0717029449424, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI3868720, Length=464, Percent_Identity=26.0775862068966, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI3868719, Length=463, Percent_Identity=23.9740820734341, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788534, Length=881, Percent_Identity=23.2690124858116, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787741, Length=317, Percent_Identity=23.6593059936909, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011888
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 89937; Mature: 89806

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQESPGGVSRRALLKSTALGSLALAAGGLTLPFTLRRAAAAVQQATGDNTRIVWGACS
CCCCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEE
VNCGSRCALRLHVRDDEVVYVETDNTGDDRYGDHQVRACLRGRSIRRRINHPDRLNYPMK
CCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RVGKRGEGKFVRISWQEALDTLADRLKSVVAQYGNEAVYINYSSGIVGGNITRSSPSASP
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCHHH
VARLMNCYGGSLNQYGTYSTAQIACAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETRM
HHHHHHHHCCCCCCCCCCCCEEEEEEECCEECCCCCCCCCCCCCCEEEEEECCCCHHCEE
SGGGITWYLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINE
CCCCEEEEEHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHEEHEEECC
DLVDQPFLDKYCVGYDEKTLPAGAPANGHYKAYILGEGDDGIAKTPQWASRLTGIPTDRI
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHH
IKLAREIGMSKPAYICQGWGPQRQANGELTARAIAMLPILTGNVGINGGNSGARESTYTI
HHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHEEECCEECCCCCCCCCCCEEEE
TIERLPVLENPVKTAISCFTWTDAIARGPEMTASRDGVRGKEKLDVPIKFLWNYAGNTII
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHEECCCCCCEE
NQHSDINKTHEILQDESKCETIVVIDNFMTSSAKYADLLLPDLMTVEQEDIIPNDYAGNM
CCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCE
GYLIFIQPATSAKFERKPIYWILSEVAKRLGDDVHQRFTEGRTQEQWLQYLYAKMVAKDP
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
ALPAYEDLKRMGIYKRKDPNGHFVAYRDFRRDPEAHPLKTPSGKIEIYSSRLAEIAARWQ
CCCCHHHHHHCCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHC
LEKDEVISPLPVYASTFEGWDDPLRSQYPLQLFGFHYKARTHSSYGNVDVLQAACRQEVW
CCHHHCCCCCCHHHHHCCCCCCHHCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHC
INPLDAEKRGIKNGDMVRVFNQRGEVRLPAKVTPRIMPGVSAMGQGAWHDANMTGDRIDH
CCCCCHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCC
GACMNTLTTHRPSPLAKGNPQHTNLVDIEKV
CHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
SNQESPGGVSRRALLKSTALGSLALAAGGLTLPFTLRRAAAAVQQATGDNTRIVWGACS
CCCCCCCCHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEE
VNCGSRCALRLHVRDDEVVYVETDNTGDDRYGDHQVRACLRGRSIRRRINHPDRLNYPMK
CCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RVGKRGEGKFVRISWQEALDTLADRLKSVVAQYGNEAVYINYSSGIVGGNITRSSPSASP
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCHHH
VARLMNCYGGSLNQYGTYSTAQIACAMPYTYGSNDGNSTSDIENSKLVVMFGNNPAETRM
HHHHHHHHCCCCCCCCCCCCEEEEEEECCEECCCCCCCCCCCCCCEEEEEECCCCHHCEE
SGGGITWYLEQARERSNARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGIAWVLINE
CCCCEEEEEHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHEEHEEECC
DLVDQPFLDKYCVGYDEKTLPAGAPANGHYKAYILGEGDDGIAKTPQWASRLTGIPTDRI
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCHHHH
IKLAREIGMSKPAYICQGWGPQRQANGELTARAIAMLPILTGNVGINGGNSGARESTYTI
HHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHEEECCEECCCCCCCCCCCEEEE
TIERLPVLENPVKTAISCFTWTDAIARGPEMTASRDGVRGKEKLDVPIKFLWNYAGNTII
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHEECCCCCCEE
NQHSDINKTHEILQDESKCETIVVIDNFMTSSAKYADLLLPDLMTVEQEDIIPNDYAGNM
CCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCE
GYLIFIQPATSAKFERKPIYWILSEVAKRLGDDVHQRFTEGRTQEQWLQYLYAKMVAKDP
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
ALPAYEDLKRMGIYKRKDPNGHFVAYRDFRRDPEAHPLKTPSGKIEIYSSRLAEIAARWQ
CCCCHHHHHHCCCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHC
LEKDEVISPLPVYASTFEGWDDPLRSQYPLQLFGFHYKARTHSSYGNVDVLQAACRQEVW
CCHHHCCCCCCHHHHHCCCCCCHHCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHC
INPLDAEKRGIKNGDMVRVFNQRGEVRLPAKVTPRIMPGVSAMGQGAWHDANMTGDRIDH
CCCCCHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCC
GACMNTLTTHRPSPLAKGNPQHTNLVDIEKV
CHHHHHHHCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]