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The map label for this gene is ttdT [H]

Identifier: 238894565

GI number: 238894565

Start: 2462278

End: 2463804

Strand: Reverse

Name: ttdT [H]

Synonym: KP1_2563

Alternate gene names: 238894565

Gene position: 2463804-2462278 (Counterclockwise)

Preceding gene: 238894569

Following gene: 238894564

Centisome position: 46.94

GC content: 59.2

Gene sequence:

>1527_bases
TTGCAGATACTCATTATGAAAGAGAAAAAGACAACCATACCGCCTGCCGGTGCAGTCAAGCCAACGACTGCGAATAAAAA
ACCTCTCCTGATGATGGCGCTGCCGATTATCGTTGCCGTGCTGTTATTGTTCGTCCCGGTCCCCGAAGGCCTGCCGCCGT
ACGCCTGGCACTACTTCGCTATCTTTGTCGGGGTGATCGTCGGGTTGATTTTTGAACCGCTGCCCGGCGCCGTTATCGGT
ATCACCGGCGTGGTAGTTATTGCCTTGTGCAGCCAGTGGCTGCTGTTCAGCCCGGATCAGATGGCCGCGCCAGGCTTCAA
AATGGCTGGCGCCTCCTTTAAGTGGGCGGTGAGCGGCTTCGGCAACTCCACCGTGTGGCTTATCTTCGGCGCGTTCATGT
TCGCCGCCGGCTACGATAAAACGCAGTTCGGCCGCCGCCTGGCGCTGATTCTGGTGAAATATCTTGGCCGTCGCAGCCTG
ACGCTCGGCTACGCCATCACCTTCGCGGATCTGCTGCTGGCGCCGTTTACGCCGTCTAACACCGCACGCAGCGGGGGGAC
TATCTACCCGATTATCGCTAACCTGCCGCCGCTGTACGGTTCAAAGCCAAACGATCCGAGCGCACGTAAAATCGGTTCCT
ATCTGATGTGGGTAGCGATCACCGCCGCCTGTATTACCAGCTCGATGTTCCTGTCGGCTCTGGCCCCGAACCTGCTGGCC
CTGGCGCTGGTCAAAAGCATTGTTGGCATCAATATCTCCTGGGGCACCTGGTTCATCGCCTTCCTGCCGCTGGGTATCCT
GCTGATTCTGGCCATGCCGCTGCTGGCCTACTGGTTCTACCCGCCGGAAGTGAAAGTCAATAACGAAGTGCCGCTGTGGG
CCGCGCGTGAACTGGAAAAACTGGGCAAACTGTCGCGCAATGAAATTCTGCTGCTGGTATTCGTCTGCTTCGCGCTGATG
ATGTGGATCTTCGCCGCCGACTGGATCGAACCGGCGCTGGCTGCCCTGCTGGTTATCGTGCTGATGCTGTGGACCGGCGT
GCTCTCCTGGAGCGATATCACCAACAACAAAGCGGCATGGAACACCTTTGTCTGGTTCGCCACCCTGGTGGCACTGGCCG
ACGGCCTCTCCTCCACCGGCTTTATCGCCTGGCTGGGTAAAGAGGGCGGCGCGCTGATGAGCGGCATCTCCCCGGGGATG
GCGACCATCGTCCTGCTGCTGGCGTTCTACCTGCTGCACTATCTGTTTGCCAGCACCACCGCGCACACCACCGCGCTGCT
GCCGGCCATGCTGACCATTGCCTCGACTATCCCGGGAATGAATATGGAAGTGTTTGTCCTGCTGATGGTCACCTCGCTGG
GCGTGATGGGGATCATCACCCCGTACGGTACTGGCCCAAGCCCAATCTACTACGGCAGCGGCTACCTGCCGACCAAAGAT
TACTGGCGCCTCGGCACCATCTTTGGCGCCATCTTCCTGGCCGCCCTGCTGCTGATCGGCTATCCGTGGATGTCCATGAT
GTTCTGA

Upstream 100 bases:

>100_bases
CCCTGTCGATACTCAGAAACGCAAAATAAAAACTAAAGTAACTTTTGTAATTAAAGAAACCACTGAGCAAGACGCTGGCG
TAGACGTTATTTTCAACAAC

Downstream 100 bases:

>100_bases
TTCATAACCGCCGGGACTACCCCGGCGGTTTTTATCTTTATGGAGTAAGTGACTATGTCGACTAAACCGTTTGTTTATCA
GGATCCGTTTCCTCTGGCGC

Product: putative tartrate:succinate antiporter

Products: tartrate [Cytoplasm]; succinate [Periplasm] [C]

Alternate protein names: Tartrate carrier; Tartrate transporter [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MQILIMKEKKTTIPPAGAVKPTTANKKPLLMMALPIIVAVLLLFVPVPEGLPPYAWHYFAIFVGVIVGLIFEPLPGAVIG
ITGVVVIALCSQWLLFSPDQMAAPGFKMAGASFKWAVSGFGNSTVWLIFGAFMFAAGYDKTQFGRRLALILVKYLGRRSL
TLGYAITFADLLLAPFTPSNTARSGGTIYPIIANLPPLYGSKPNDPSARKIGSYLMWVAITAACITSSMFLSALAPNLLA
LALVKSIVGINISWGTWFIAFLPLGILLILAMPLLAYWFYPPEVKVNNEVPLWAARELEKLGKLSRNEILLLVFVCFALM
MWIFAADWIEPALAALLVIVLMLWTGVLSWSDITNNKAAWNTFVWFATLVALADGLSSTGFIAWLGKEGGALMSGISPGM
ATIVLLLAFYLLHYLFASTTAHTTALLPAMLTIASTIPGMNMEVFVLLMVTSLGVMGIITPYGTGPSPIYYGSGYLPTKD
YWRLGTIFGAIFLAALLLIGYPWMSMMF

Sequences:

>Translated_508_residues
MQILIMKEKKTTIPPAGAVKPTTANKKPLLMMALPIIVAVLLLFVPVPEGLPPYAWHYFAIFVGVIVGLIFEPLPGAVIG
ITGVVVIALCSQWLLFSPDQMAAPGFKMAGASFKWAVSGFGNSTVWLIFGAFMFAAGYDKTQFGRRLALILVKYLGRRSL
TLGYAITFADLLLAPFTPSNTARSGGTIYPIIANLPPLYGSKPNDPSARKIGSYLMWVAITAACITSSMFLSALAPNLLA
LALVKSIVGINISWGTWFIAFLPLGILLILAMPLLAYWFYPPEVKVNNEVPLWAARELEKLGKLSRNEILLLVFVCFALM
MWIFAADWIEPALAALLVIVLMLWTGVLSWSDITNNKAAWNTFVWFATLVALADGLSSTGFIAWLGKEGGALMSGISPGM
ATIVLLLAFYLLHYLFASTTAHTTALLPAMLTIASTIPGMNMEVFVLLMVTSLGVMGIITPYGTGPSPIYYGSGYLPTKD
YWRLGTIFGAIFLAALLLIGYPWMSMMF
>Mature_508_residues
MQILIMKEKKTTIPPAGAVKPTTANKKPLLMMALPIIVAVLLLFVPVPEGLPPYAWHYFAIFVGVIVGLIFEPLPGAVIG
ITGVVVIALCSQWLLFSPDQMAAPGFKMAGASFKWAVSGFGNSTVWLIFGAFMFAAGYDKTQFGRRLALILVKYLGRRSL
TLGYAITFADLLLAPFTPSNTARSGGTIYPIIANLPPLYGSKPNDPSARKIGSYLMWVAITAACITSSMFLSALAPNLLA
LALVKSIVGINISWGTWFIAFLPLGILLILAMPLLAYWFYPPEVKVNNEVPLWAARELEKLGKLSRNEILLLVFVCFALM
MWIFAADWIEPALAALLVIVLMLWTGVLSWSDITNNKAAWNTFVWFATLVALADGLSSTGFIAWLGKEGGALMSGISPGM
ATIVLLLAFYLLHYLFASTTAHTTALLPAMLTIASTIPGMNMEVFVLLMVTSLGVMGIITPYGTGPSPIYYGSGYLPTKD
YWRLGTIFGAIFLAALLLIGYPWMSMMF

Specific function: Catalyzes the uptake of tartrate in exchange for intracellular succinate. Essential for anaerobic L-tartrate fermentation [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. SODIT1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789444, Length=486, Percent_Identity=54.320987654321, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1786829, Length=472, Percent_Identity=49.364406779661, Blast_Score=492, Evalue=1e-140,
Organism=Escherichia coli, GI1786986, Length=488, Percent_Identity=34.4262295081967, Blast_Score=257, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 55127; Mature: 55127

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQILIMKEKKTTIPPAGAVKPTTANKKPLLMMALPIIVAVLLLFVPVPEGLPPYAWHYFA
CEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IFVGVIVGLIFEPLPGAVIGITGVVVIALCSQWLLFSPDQMAAPGFKMAGASFKWAVSGF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCEECCCCCEEEEECC
GNSTVWLIFGAFMFAAGYDKTQFGRRLALILVKYLGRRSLTLGYAITFADLLLAPFTPSN
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
TARSGGTIYPIIANLPPLYGSKPNDPSARKIGSYLMWVAITAACITSSMFLSALAPNLLA
CCCCCCEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALVKSIVGINISWGTWFIAFLPLGILLILAMPLLAYWFYPPEVKVNNEVPLWAARELEK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHH
LGKLSRNEILLLVFVCFALMMWIFAADWIEPALAALLVIVLMLWTGVLSWSDITNNKAAW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
NTFVWFATLVALADGLSSTGFIAWLGKEGGALMSGISPGMATIVLLLAFYLLHYLFASTT
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AHTTALLPAMLTIASTIPGMNMEVFVLLMVTSLGVMGIITPYGTGPSPIYYGSGYLPTKD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEECCCCCCCHH
YWRLGTIFGAIFLAALLLIGYPWMSMMF
HHHHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MQILIMKEKKTTIPPAGAVKPTTANKKPLLMMALPIIVAVLLLFVPVPEGLPPYAWHYFA
CEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IFVGVIVGLIFEPLPGAVIGITGVVVIALCSQWLLFSPDQMAAPGFKMAGASFKWAVSGF
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCEECCCCCEEEEECC
GNSTVWLIFGAFMFAAGYDKTQFGRRLALILVKYLGRRSLTLGYAITFADLLLAPFTPSN
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
TARSGGTIYPIIANLPPLYGSKPNDPSARKIGSYLMWVAITAACITSSMFLSALAPNLLA
CCCCCCEEEEHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALVKSIVGINISWGTWFIAFLPLGILLILAMPLLAYWFYPPEVKVNNEVPLWAARELEK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHH
LGKLSRNEILLLVFVCFALMMWIFAADWIEPALAALLVIVLMLWTGVLSWSDITNNKAAW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
NTFVWFATLVALADGLSSTGFIAWLGKEGGALMSGISPGMATIVLLLAFYLLHYLFASTT
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AHTTALLPAMLTIASTIPGMNMEVFVLLMVTSLGVMGIITPYGTGPSPIYYGSGYLPTKD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEECCCCCCCHH
YWRLGTIFGAIFLAALLLIGYPWMSMMF
HHHHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: tartrate [Periplasm]; succinate [Cytoplasm] [C]

Specific reaction: tartrate [Periplasm] + succinate [Cytoplasm] = tartrate [Cytoplasm] + succinate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]