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The map label for this gene is sapB [H]

Identifier: 238894352

GI number: 238894352

Start: 2242467

End: 2243432

Strand: Reverse

Name: sapB [H]

Synonym: KP1_2334

Alternate gene names: 238894352

Gene position: 2243432-2242467 (Counterclockwise)

Preceding gene: 238894353

Following gene: 238894351

Centisome position: 42.74

GC content: 58.9

Gene sequence:

>966_bases
ATGATTATTTTTACCCTGCGCCGTCTGCTGCTGCTGCTGATCACCCTCTTTTTTCTGACCTTTGTCGGTTTCAGCCTGAG
CTATTTCACCCCTCATGCCCCACTGCAGGGCGCTTCCCTGTGGAATGCGTGGCTGTTCTGGTTTGAAGGGGTGCTGCACT
GGGATTTCGGCGTCTCCAGCATTAACGGCCAGCTGATTTCTGAGCAGTTGCGCGAGGTGTTCCCGGCGACCATGGAGCTG
TGCATCCTCGCCTTCGGCTTTGCCCTGCTGATAGGCATTCCGGTGGGGATGATCGCCGGCGTAATGCGCAATAAATGGCC
CGATACCCTGATCAGCGCCGTCGCGCTGGTCGGTTTCTCGATCCCGGTCTTCTGGCTGGCGCTGCTCCTGACCCTCTTCT
TTTCCCTGACCCTCGGCTGGCTTCCGGTCTCCGGTCGCTTCGATCTGCTGTATGAGGTGAAAAACGTCACCGGTTTCGCG
CTGATCGACGCCTGGCTTTCGGACTCGCCGTGGCGCCATGAGATGATCGTCAGCGCCGCCCGGCATATGGTGCTGCCGGT
ATTGACCCTGGCGGTCGCCCCCACCACTGAAGTGATCCGCCTGATGCGCATTAGCACCAGCGAGGTGTATGACACTAACT
ATGTAAAAGCGGCCGCCACCCGCGGCGTGTCGCGACGCAAAATTCTACTGCGCCATGTGCTGCACAACGCCCTGCCGCCG
GTGATCCCGCGTCTCGGCCTGCAGTTTTCCACCATGCTCACCCTGGCGATGATCACTGAGATGGTGTTCAGCTGGCCTGG
ACTGGGCCGCTGGCTGATCAACGCCATTCGCCAGCAGGACTACGCGGCGATCTCCGCCGGAGTGATGGTGATTGGCGCGC
TGGTGATTATTGTCAACGTGATTTCCGATATTCTCGGTGCCATGGCTAACCCACTGAAACATAAGGAATGGTATGCCCTA
CGATAG

Upstream 100 bases:

>100_bases
AGGCCTACCGCTATGATATGAAAGGCCTGGTGCTCAGCCCTTTCGGTAACGCTTCGTTCGCTGGCGTATCGAGGGAAAAT
ACCGAAGAGGTGAAAAAGCC

Downstream 100 bases:

>100_bases
CGTTTATCTGGAAAAGCGTCCGCCCGGCGCGCTGCGCACCGTATGGCGTAAGTTCTATGGCGACACCACGGCGATGATCG
GTCTGTACGGCTGCGCGGGC

Product: ABC-type peptide transport system permease component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIIFTLRRLLLLLITLFFLTFVGFSLSYFTPHAPLQGASLWNAWLFWFEGVLHWDFGVSSINGQLISEQLREVFPATMEL
CILAFGFALLIGIPVGMIAGVMRNKWPDTLISAVALVGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKNVTGFA
LIDAWLSDSPWRHEMIVSAARHMVLPVLTLAVAPTTEVIRLMRISTSEVYDTNYVKAAATRGVSRRKILLRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVIGALVIIVNVISDILGAMANPLKHKEWYAL
R

Sequences:

>Translated_321_residues
MIIFTLRRLLLLLITLFFLTFVGFSLSYFTPHAPLQGASLWNAWLFWFEGVLHWDFGVSSINGQLISEQLREVFPATMEL
CILAFGFALLIGIPVGMIAGVMRNKWPDTLISAVALVGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKNVTGFA
LIDAWLSDSPWRHEMIVSAARHMVLPVLTLAVAPTTEVIRLMRISTSEVYDTNYVKAAATRGVSRRKILLRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVIGALVIIVNVISDILGAMANPLKHKEWYAL
R
>Mature_321_residues
MIIFTLRRLLLLLITLFFLTFVGFSLSYFTPHAPLQGASLWNAWLFWFEGVLHWDFGVSSINGQLISEQLREVFPATMEL
CILAFGFALLIGIPVGMIAGVMRNKWPDTLISAVALVGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKNVTGFA
LIDAWLSDSPWRHEMIVSAARHMVLPVLTLAVAPTTEVIRLMRISTSEVYDTNYVKAAATRGVSRRKILLRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVIGALVIIVNVISDILGAMANPLKHKEWYAL
R

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=321, Percent_Identity=88.1619937694704, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1789965, Length=344, Percent_Identity=34.3023255813954, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1787053, Length=337, Percent_Identity=29.673590504451, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787761, Length=242, Percent_Identity=39.2561983471074, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787497, Length=332, Percent_Identity=28.0120481927711, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789888, Length=275, Percent_Identity=29.8181818181818, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1788504, Length=261, Percent_Identity=26.0536398467433, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35954; Mature: 35954

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFTLRRLLLLLITLFFLTFVGFSLSYFTPHAPLQGASLWNAWLFWFEGVLHWDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
INGQLISEQLREVFPATMELCILAFGFALLIGIPVGMIAGVMRNKWPDTLISAVALVGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKNVTGFALIDAWLSDSPWRHEMIVSAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHH
RHMVLPVLTLAVAPTTEVIRLMRISTSEVYDTNYVKAAATRGVSRRKILLRHVLHNALPP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCH
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVIGALVIIVNV
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISDILGAMANPLKHKEWYALR
HHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIIFTLRRLLLLLITLFFLTFVGFSLSYFTPHAPLQGASLWNAWLFWFEGVLHWDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
INGQLISEQLREVFPATMELCILAFGFALLIGIPVGMIAGVMRNKWPDTLISAVALVGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKNVTGFALIDAWLSDSPWRHEMIVSAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHH
RHMVLPVLTLAVAPTTEVIRLMRISTSEVYDTNYVKAAATRGVSRRKILLRHVLHNALPP
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCH
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVIGALVIIVNV
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISDILGAMANPLKHKEWYALR
HHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]