Click here to switch to the map view.

The map label for this gene is sapC [H]

Identifier: 238894351

GI number: 238894351

Start: 2241590

End: 2242480

Strand: Reverse

Name: sapC [H]

Synonym: KP1_2333

Alternate gene names: 238894351

Gene position: 2242480-2241590 (Counterclockwise)

Preceding gene: 238894352

Following gene: 238894350

Centisome position: 42.73

GC content: 64.2

Gene sequence:

>891_bases
ATGCCCTACGATAGCGTTTATCTGGAAAAGCGTCCGCCCGGCGCGCTGCGCACCGTATGGCGTAAGTTCTATGGCGACAC
CACGGCGATGATCGGTCTGTACGGCTGCGCGGGCCTGCTGCTGCTCTGCGTCTTCGGCGGCTGGTTCGCCCCCTACGGCA
TCGACCAGCAGTTCCTCGGCTACCAGCTGTTGCCGCCGTCGTGGTCGCGCTATGGCGAAGTCTCCTTCTTTCTGGGAACC
GATGACCTCGGCCGCGATGTGCTGAGCCGACTGCTGAGCGGCGCGGCGCCCACCGTCGGCGGCGCTTTTGTCGTCACCCT
CGGCGCCACGCTGTTTGGTCTGGTGCTGGGCGTGATTGCCGGATCGACCCACGGCCTGCGCTCGGCGGTGATGAACCATA
TCCTCGACACCCTGCTCTCCATCCCCTCGCTGCTGCTGGCGATTATCGTCGTCGCCTTTGCCGGGCCGCATCTCAGCCAT
GCGATGTTCGCCGTCTGGCTGGCGCTGCTGCCGCGCATGGTGCGCTCCGTCTACAGCATGGTCCACGATGAGCTGGAGAA
AGAGTACATCATCGCCGCCCGCCTCGACGGCGCCTCGACGCTGAATATTCTGCTGTTCGCCATCCTGCCCAATATCGCCT
CCGGCCTGGTGACCGAGATCACTCGCGCCCTGTCGATGGCCATTCTGGATATTGCCGCGCTGGGCTTTCTTGATCTCGGC
GCCCAGCTGCCTTCGCCGGAATGGGGAGCCATGCTGGGCGATGCGCTGGAGCTTATCTATGTGGCGCCGTGGACCGTGAT
GCTCCCCGGGGCGGCGATTATGCTCAGCGTACTGCTGGTCAACCTGCTGGGCGACGGTATTCGCCGGGCGATCATTGCCG
GGGTAGAATAA

Upstream 100 bases:

>100_bases
TCCGCCGGAGTGATGGTGATTGGCGCGCTGGTGATTATTGTCAACGTGATTTCCGATATTCTCGGTGCCATGGCTAACCC
ACTGAAACATAAGGAATGGT

Downstream 100 bases:

>100_bases
TGCCGTTACTCGATATTCGTCACTTAACCATTGAATTTAAAACCAGCGAAGGCTGGGTAAAAGCCGTCGATCGCGTCAGC
CTGACGCTGACCGAAGGCGA

Product: ABC-type peptide transport system permease component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPYDSVYLEKRPPGALRTVWRKFYGDTTAMIGLYGCAGLLLLCVFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFVVTLGATLFGLVLGVIAGSTHGLRSAVMNHILDTLLSIPSLLLAIIVVAFAGPHLSH
AMFAVWLALLPRMVRSVYSMVHDELEKEYIIAARLDGASTLNILLFAILPNIASGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAIIAGVE

Sequences:

>Translated_296_residues
MPYDSVYLEKRPPGALRTVWRKFYGDTTAMIGLYGCAGLLLLCVFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFVVTLGATLFGLVLGVIAGSTHGLRSAVMNHILDTLLSIPSLLLAIIVVAFAGPHLSH
AMFAVWLALLPRMVRSVYSMVHDELEKEYIIAARLDGASTLNILLFAILPNIASGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAIIAGVE
>Mature_295_residues
PYDSVYLEKRPPGALRTVWRKFYGDTTAMIGLYGCAGLLLLCVFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTD
DLGRDVLSRLLSGAAPTVGGAFVVTLGATLFGLVLGVIAGSTHGLRSAVMNHILDTLLSIPSLLLAIIVVAFAGPHLSHA
MFAVWLALLPRMVRSVYSMVHDELEKEYIIAARLDGASTLNILLFAILPNIASGLVTEITRALSMAILDIAALGFLDLGA
QLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAIIAGVE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=90.5405405405405, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1789964, Length=280, Percent_Identity=40.3571428571429, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=36.6197183098592, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1787760, Length=250, Percent_Identity=36.4, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789889, Length=241, Percent_Identity=29.8755186721992, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787498, Length=219, Percent_Identity=30.5936073059361, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788505, Length=222, Percent_Identity=28.8288288288288, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31660; Mature: 31529

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYDSVYLEKRPPGALRTVWRKFYGDTTAMIGLYGCAGLLLLCVFGGWFAPYGIDQQFLG
CCCCCCEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLGATLFGLVLGVIA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GSTHGLRSAVMNHILDTLLSIPSLLLAIIVVAFAGPHLSHAMFAVWLALLPRMVRSVYSM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYIIAARLDGASTLNILLFAILPNIASGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PYDSVYLEKRPPGALRTVWRKFYGDTTAMIGLYGCAGLLLLCVFGGWFAPYGIDQQFLG
CCCCCEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLGATLFGLVLGVIA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GSTHGLRSAVMNHILDTLLSIPSLLLAIIVVAFAGPHLSHAMFAVWLALLPRMVRSVYSM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYIIAARLDGASTLNILLFAILPNIASGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]