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The map label for this gene is sapD [H]

Identifier: 238894350

GI number: 238894350

Start: 2240598

End: 2241590

Strand: Reverse

Name: sapD [H]

Synonym: KP1_2332

Alternate gene names: 238894350

Gene position: 2241590-2240598 (Counterclockwise)

Preceding gene: 238894351

Following gene: 238894349

Centisome position: 42.71

GC content: 59.82

Gene sequence:

>993_bases
ATGCCGTTACTCGATATTCGTCACTTAACCATTGAATTTAAAACCAGCGAAGGCTGGGTAAAAGCCGTCGATCGCGTCAG
CCTGACGCTGACCGAAGGCGAAATCCGCGGCCTGGTGGGGGAATCCGGCTCCGGGAAAAGCCTTATTGCCAAAGCTATCT
GCGGCGTGACCAAAGACAACTGGCGGGTCACGGCCGACCGCATGCGCTTCGATGACATTGACCTGCTGCGACTGTCGAAC
CGCGAGCGCCGGAAGCTGATCGGCCATAACGTGTCGATGATTTTTCAGGAGCCCCAGTCGTGCCTCGATCCCTCTGAGCG
CATCGGCCAGCAGCTGATTCAGAGTATCCCCGGCTGGACCTACAAGGGCCGCTGGTGGCAACGGCTGGGCTGGCGCAAGC
GCCGGGCCATCGAGCTGTTGCACCGCGTCGGCATTAAAGATCACAAAGATGCCATGCGCAGCTTCCCTTATCAGCTGACC
GAGGGCGAGTGCCAGAAGGTGATGATCGCCATCGCCCTGGCCAACCAGCCGCGTCTGCTGATTGCCGACGAGCCGACCAA
CGCCATGGAGCCGACCACCCAGGCGCAGATTATTCGCCTGCTGACGCGGCTCAACCAGAACAACAACACCACCATCTTGC
TGATCAGCCATGACCTGCAAATGCTCAGCAAATGGGCGGATAAAATCAACGTCATGTACTGCGGGCAGACGGTGGAGAGC
GGGCCCAGCGAAGAGCTGATCACTCTCCCACATCACCCCTACACCCAGGCGTTAATCCGCGCGATCCCGGATTTCGGTAG
CGCCATGCCGCATAAAAGTCGCCTCAACACCCTGCCTGGAGCGATCCCGCTGCTGGAGCAGTTGCCTATCGGCTGTCGGC
TAGGGCCGCGCTGCCCGTACGCCCAGCGCGAGTGTATCGAAACGCCGCGTCTTACCGGGGCGCGCAACCATCTGTACGCC
TGTCATTTCCCGTTGAACATGGAGAAAGAGTGA

Upstream 100 bases:

>100_bases
GGACCGTGATGCTCCCCGGGGCGGCGATTATGCTCAGCGTACTGCTGGTCAACCTGCTGGGCGACGGTATTCGCCGGGCG
ATCATTGCCGGGGTAGAATA

Downstream 100 bases:

>100_bases
AATGGTCGAAACATTGCTGGAAGTTCGCCAACTCAGTAAGACCTTTCGCTACCGCACCGGCTGGTTTCACCGTCAGACGG
TTGAGGCGGTTAAGCCGCTG

Product: ABC-type peptide transport system ATP-binding component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPLLDIRHLTIEFKTSEGWVKAVDRVSLTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSN
RERRKLIGHNVSMIFQEPQSCLDPSERIGQQLIQSIPGWTYKGRWWQRLGWRKRRAIELLHRVGIKDHKDAMRSFPYQLT
EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIIRLLTRLNQNNNTTILLISHDLQMLSKWADKINVMYCGQTVES
GPSEELITLPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIETPRLTGARNHLYA
CHFPLNMEKE

Sequences:

>Translated_330_residues
MPLLDIRHLTIEFKTSEGWVKAVDRVSLTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSN
RERRKLIGHNVSMIFQEPQSCLDPSERIGQQLIQSIPGWTYKGRWWQRLGWRKRRAIELLHRVGIKDHKDAMRSFPYQLT
EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIIRLLTRLNQNNNTTILLISHDLQMLSKWADKINVMYCGQTVES
GPSEELITLPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIETPRLTGARNHLYA
CHFPLNMEKE
>Mature_329_residues
PLLDIRHLTIEFKTSEGWVKAVDRVSLTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSNR
ERRKLIGHNVSMIFQEPQSCLDPSERIGQQLIQSIPGWTYKGRWWQRLGWRKRRAIELLHRVGIKDHKDAMRSFPYQLTE
GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIIRLLTRLNQNNNTTILLISHDLQMLSKWADKINVMYCGQTVESG
PSEELITLPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIETPRLTGARNHLYAC
HFPLNMEKE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=91.8181818181818, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=44.5121951219512, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=38.719512195122, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI48994883, Length=324, Percent_Identity=37.037037037037, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1787500, Length=329, Percent_Identity=34.6504559270517, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI145693107, Length=271, Percent_Identity=34.6863468634686, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1788506, Length=273, Percent_Identity=37.3626373626374, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787758, Length=314, Percent_Identity=32.1656050955414, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789962, Length=329, Percent_Identity=30.6990881458967, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1787547, Length=276, Percent_Identity=29.7101449275362, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789890, Length=241, Percent_Identity=30.7053941908714, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994997, Length=267, Percent_Identity=29.5880149812734, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786398, Length=285, Percent_Identity=29.4736842105263, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789891, Length=232, Percent_Identity=32.3275862068966, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789032, Length=245, Percent_Identity=28.1632653061224, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789873, Length=227, Percent_Identity=30.8370044052863, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081791, Length=273, Percent_Identity=28.9377289377289, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788450, Length=257, Percent_Identity=26.8482490272374, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87081834, Length=224, Percent_Identity=30.3571428571429, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790544, Length=240, Percent_Identity=28.75, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788225, Length=235, Percent_Identity=27.2340425531915, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790162, Length=260, Percent_Identity=24.2307692307692, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787105, Length=252, Percent_Identity=28.1746031746032, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787089, Length=224, Percent_Identity=29.4642857142857, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786872, Length=226, Percent_Identity=27.8761061946903, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789672, Length=248, Percent_Identity=26.2096774193548, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787029, Length=244, Percent_Identity=25.4098360655738, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789864, Length=252, Percent_Identity=26.5873015873016, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787792, Length=251, Percent_Identity=29.4820717131474, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787370, Length=254, Percent_Identity=26.3779527559055, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788644, Length=188, Percent_Identity=25, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994943, Length=248, Percent_Identity=25.4032258064516, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786345, Length=223, Percent_Identity=26.0089686098655, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081709, Length=259, Percent_Identity=23.1660231660232, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082268, Length=231, Percent_Identity=25.974025974026, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790739, Length=243, Percent_Identity=25.5144032921811, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786563, Length=255, Percent_Identity=26.2745098039216, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787112, Length=243, Percent_Identity=26.7489711934156, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI48995001, Length=226, Percent_Identity=27.4336283185841, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082267, Length=246, Percent_Identity=22.7642276422764, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790467, Length=245, Percent_Identity=24.8979591836735, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786253, Length=226, Percent_Identity=26.1061946902655, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786975, Length=240, Percent_Identity=26.25, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=241, Percent_Identity=27.3858921161826, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25146777, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=256, Percent_Identity=24.21875, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=256, Percent_Identity=24.21875, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=256, Percent_Identity=24.21875, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37596; Mature: 37465

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRHLTIEFKTSEGWVKAVDRVSLTLTEGEIRGLVGESGSGKSLIAKAICGVTKDN
CCCEEEEEEEEEEECCCCHHHHHHHEEEEEECCHHHEECCCCCCCHHHHHHHHHCCCCCC
WRVTADRMRFDDIDLLRLSNRERRKLIGHNVSMIFQEPQSCLDPSERIGQQLIQSIPGWT
CEEEHHHCCCCCCHHHHHCCHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCC
YKGRWWQRLGWRKRRAIELLHRVGIKDHKDAMRSFPYQLTEGECQKVMIAIALANQPRLL
CCCHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIIRLLTRLNQNNNTTILLISHDLQMLSKWADKINVMYCGQTVES
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHEEEEEECCHHCC
GPSEELITLPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPY
CCCCCEEECCCCHHHHHHHHHCCHHCCCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCC
AQRECIETPRLTGARNHLYACHFPLNMEKE
HHHHHHCCCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PLLDIRHLTIEFKTSEGWVKAVDRVSLTLTEGEIRGLVGESGSGKSLIAKAICGVTKDN
CCEEEEEEEEEEECCCCHHHHHHHEEEEEECCHHHEECCCCCCCHHHHHHHHHCCCCCC
WRVTADRMRFDDIDLLRLSNRERRKLIGHNVSMIFQEPQSCLDPSERIGQQLIQSIPGWT
CEEEHHHCCCCCCHHHHHCCHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCC
YKGRWWQRLGWRKRRAIELLHRVGIKDHKDAMRSFPYQLTEGECQKVMIAIALANQPRLL
CCCHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIIRLLTRLNQNNNTTILLISHDLQMLSKWADKINVMYCGQTVES
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHEEEEEECCHHCC
GPSEELITLPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPY
CCCCCEEECCCCHHHHHHHHHCCHHCCCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCC
AQRECIETPRLTGARNHLYACHFPLNMEKE
HHHHHHCCCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]