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The map label for this gene is acT [H]

Identifier: 238894091

GI number: 238894091

Start: 1991476

End: 1992381

Strand: Direct

Name: acT [H]

Synonym: KP1_2042

Alternate gene names: 238894091

Gene position: 1991476-1992381 (Clockwise)

Preceding gene: 238894088

Following gene: 238894092

Centisome position: 37.94

GC content: 64.57

Gene sequence:

>906_bases
ATGCAGGATCTCAATGACTTCGCCTGGTTTGTCCAGGTGGTAGACCATGGCGGTTTCGCCGCGGCGGGGCGAGCGCTTGA
CCAGCCGAAATCCAAACTCAGCCGTCGCATTGCGCAACTCGAGGAGCGGTTGGGCGTGCGTTTGATTCAGCGAACCACCC
GTCAGTTCGCGGTCGCCGAGGTCGGGCAGACCTTTTATCAGCATTGCAAAGCGATGCTGATTGAGGCCGAGGCGGCGCAG
CAGGCGGTCGAGACGCTGCGCGCCGAGCCGCGCGGTAGCGTCAGGATCACCTGTCCGGTCACCTTGCTGCATGTCCATAT
CGGACCGATGCTGGCGCGATTTATGGCGCGCTATCCTGGGGTAACGCTGCATCTTGAGGCGACCAACCGCCGGGTGGATG
TGGTCGGGGAGGGCATTGATGTGGCGATCCGCGTCCGTCCCCGGCCCATCGAGGATAGCGACCTGGTGATGCGCGTGCTG
GCGGACCGCGGGCACCGGCTGGTGGCCAGCCCGGATCTCATTTCCCGGCTCGGACGTCCGCAGGCGCCGTCCGAGCTGAG
CGCCTGGCCGGGGCTCAGCCTGGGTGCGAACAAGCATCAGCATAAATGGCAGCTCACCGGGCCCGGGGGAGCGAGAGCGG
AAGTGTATTTCACGCCGCGAATGGTGACCACCGATATGCTGGCGCTGCGCGAGGCGGCGATGGCCGGCGTAGGCGTGGTG
CAGCTTCCTTTACTAATGGTGCGCGATCAGCTGGCGTCAGGGGAATTAGAGGTGGTTCTGGACGAGTGGCAGCCGCGGCG
GGAAGTGATCCATGCGGTATTTGCCTCACGGCGCGGGCTGCTGCCCTCCGTCAGGGCGCTGGTGGACTACCTCAGCGAAG
AGTATCAGCGGATGGAGGAGGATTAG

Upstream 100 bases:

>100_bases
TATCGGTATCTGATGTGAATAAGCTTATATCCGGGACGACGTATGCGGTAGTGAGCAAAAATGACCTATACTGTTCCAAA
AATGGAACAATGGAGGAAGG

Downstream 100 bases:

>100_bases
CTTCGGGATTGGCTTTTCTCGAGGGGCTCCCCCCCCGGCAGAGAATATAAAAGAAAAGAGCCCGTACTTGCGTACAGGCT
CTCATCTTGAATATGGCGGT

Product: hypothetical transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MQDLNDFAWFVQVVDHGGFAAAGRALDQPKSKLSRRIAQLEERLGVRLIQRTTRQFAVAEVGQTFYQHCKAMLIEAEAAQ
QAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRRVDVVGEGIDVAIRVRPRPIEDSDLVMRVL
ADRGHRLVASPDLISRLGRPQAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALREAAMAGVGVV
QLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED

Sequences:

>Translated_301_residues
MQDLNDFAWFVQVVDHGGFAAAGRALDQPKSKLSRRIAQLEERLGVRLIQRTTRQFAVAEVGQTFYQHCKAMLIEAEAAQ
QAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRRVDVVGEGIDVAIRVRPRPIEDSDLVMRVL
ADRGHRLVASPDLISRLGRPQAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALREAAMAGVGVV
QLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED
>Mature_301_residues
MQDLNDFAWFVQVVDHGGFAAAGRALDQPKSKLSRRIAQLEERLGVRLIQRTTRQFAVAEVGQTFYQHCKAMLIEAEAAQ
QAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPGVTLHLEATNRRVDVVGEGIDVAIRVRPRPIEDSDLVMRVL
ADRGHRLVASPDLISRLGRPQAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALREAAMAGVGVV
QLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEED

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=303, Percent_Identity=31.023102310231, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=28.135593220339, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=26.3698630136986, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=27.3037542662116, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081978, Length=296, Percent_Identity=30.4054054054054, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789440, Length=261, Percent_Identity=28.735632183908, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=26.962457337884, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI157672245, Length=142, Percent_Identity=35.2112676056338, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786448, Length=254, Percent_Identity=27.9527559055118, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788706, Length=259, Percent_Identity=26.2548262548263, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=148, Percent_Identity=29.7297297297297, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33601; Mature: 33601

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLNDFAWFVQVVDHGGFAAAGRALDQPKSKLSRRIAQLEERLGVRLIQRTTRQFAVAE
CCCHHHHHHHHHHHHCCCHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGQTFYQHCKAMLIEAEAAQQAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHEEHHHHHHHHHHHHHHCCC
VTLHLEATNRRVDVVGEGIDVAIRVRPRPIEDSDLVMRVLADRGHRLVASPDLISRLGRP
EEEEEECCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCC
QAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALREAAMAGVGVV
CCCCHHCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHH
QLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEE
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
D
C
>Mature Secondary Structure
MQDLNDFAWFVQVVDHGGFAAAGRALDQPKSKLSRRIAQLEERLGVRLIQRTTRQFAVAE
CCCHHHHHHHHHHHHCCCHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGQTFYQHCKAMLIEAEAAQQAVETLRAEPRGSVRITCPVTLLHVHIGPMLARFMARYPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHEEHHHHHHHHHHHHHHCCC
VTLHLEATNRRVDVVGEGIDVAIRVRPRPIEDSDLVMRVLADRGHRLVASPDLISRLGRP
EEEEEECCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCC
QAPSELSAWPGLSLGANKHQHKWQLTGPGGARAEVYFTPRMVTTDMLALREAAMAGVGVV
CCCCHHCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCHHH
QLPLLMVRDQLASGELEVVLDEWQPRREVIHAVFASRRGLLPSVRALVDYLSEEYQRMEE
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]