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The map label for this gene is ycdG [H]

Identifier: 238894071

GI number: 238894071

Start: 1968455

End: 1969777

Strand: Reverse

Name: ycdG [H]

Synonym: KP1_2020

Alternate gene names: 238894071

Gene position: 1969777-1968455 (Counterclockwise)

Preceding gene: 238894072

Following gene: 238894068

Centisome position: 37.53

GC content: 64.47

Gene sequence:

>1323_bases
ATGGCACTCTTCGATTTTCCTCGCTGGAAGCTGACCTCTCCTGCCGCCGAATCCGGCGTTGTCGCCCCCGATGAACGCTT
GTCGGCCGGGCAAACGCTGGTGATGGGCGTGCAGCACGCCGTTGCGATGTTCGGCGCGACGGTGCTGATGCCGTTGTTGA
TGGGGCTCGACCCGAACCTGTCTATTCTGATGTCGGGCGTCGGCACCCTGCTGTTCTTTGTCGTTACCGGCGGACGGGTG
CCGAGCTATCTCGGCTCCAGCGCCGCTTTTGTCGGGGTGGTGATCGCCATTACCGGCTTTAACGGCCAGGGGCTGAACCC
TCATCTGAGCGTCGCCCTTGGCGGGATCATCGCCTGCGGGCTGGTCTACACCCTGATTGGTCTGGTGGTGATGAAGATCG
GCACCCGCTGGATCGAGCGCCTGATGCCGCCGGTGGTGACCGGCGCGGTGGTGATGGCTATCGGCCTGAACCTGGCGCCG
ATTGCCGTGCGCAGCGTCTCCGCCAGCGCCTTCGACAGCTGGATGGCGGTGTTAACTGTGCTCTGCATCGGCATAGTGGC
GGTATTTACCCGCGGGATGCTGCAGCGACTGCTGATCCTGGTCGGCCTGATCGTCGCCTGCGCGCTGTACGCCCTGCTAG
CTAACGGCCTGGGCCTTGGCAAACCGCTGGACTTCTCCCCCCTCGCCCAGGCGGCGTGGTTCGGGCTGCCGCACTTTACC
ACCCCATCCTTTAACGGCCAGGCGATGATGTTGATTGCGCCGGTCGCGGTGATCCTGGTGGCCGAGAACCTCGGGCACCT
GAAGGCCGTCGCCGGGATGACCGGGCGCAATATGGACCCGTACATAGGGCGCGCCTTCGTCGGCGACGGGCTGGCGACCA
TGCTCTCCGGTTCGGTGGGCGGCAGCGGGGTCACTACCTATGCGGAGAACATCGGCGTCATGGCGGTGACCAAGGTCTAC
TCAACGCTGGTGTTTGTCGCCGCGGCGCTGATTGCCATGCTGTTGGGTTTCTCGCCGAAGTTCGGCGCATTAATCCACAC
CATTCCCGGGCCGGTGATCGGCGGCGCCTCGATCGTGGTCTTTGGCTTAATTGCCGTCGCCGGGGCGCGGATCTGGGTGC
AAAACCGGGTGGATCTGAGTCAAAACAGCAATTTGATCATGGTGTCGGTGACCCTGGTGCTGGGCGCCGGCGATTTCGCG
CTGTCGCTGGGCGGCTTTACGCTGGGCGGGATTGGCACGGCCACCTTCGGGGCGATCCTGCTGCACGCGCTGCTTCATCG
CGGGACGCGCGAGGCGAAGGAGGCCAGGGTAACGCCGGTGTAA

Upstream 100 bases:

>100_bases
CATTACCCGTCACCCGGAGCCCCGGGGACTGATGTGGTTTGACCGCGGCTATCACACGCTTATGCGACCCGCTTGTTAAC
CTTTAACCCGGGATATCATC

Downstream 100 bases:

>100_bases
GCCACATTAGCGCGGCGTTGGCGCAGGGTGCGGTGTGGGCCTGGGTGGTGTGATCCTGTAGGCCGGATAAGGCATTTATG
CCGCCATCCGGCACCACCAC

Product: putative transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MALFDFPRWKLTSPAAESGVVAPDERLSAGQTLVMGVQHAVAMFGATVLMPLLMGLDPNLSILMSGVGTLLFFVVTGGRV
PSYLGSSAAFVGVVIAITGFNGQGLNPHLSVALGGIIACGLVYTLIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVRSVSASAFDSWMAVLTVLCIGIVAVFTRGMLQRLLILVGLIVACALYALLANGLGLGKPLDFSPLAQAAWFGLPHFT
TPSFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYIGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAALIAMLLGFSPKFGALIHTIPGPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNSNLIMVSVTLVLGAGDFA
LSLGGFTLGGIGTATFGAILLHALLHRGTREAKEARVTPV

Sequences:

>Translated_440_residues
MALFDFPRWKLTSPAAESGVVAPDERLSAGQTLVMGVQHAVAMFGATVLMPLLMGLDPNLSILMSGVGTLLFFVVTGGRV
PSYLGSSAAFVGVVIAITGFNGQGLNPHLSVALGGIIACGLVYTLIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVRSVSASAFDSWMAVLTVLCIGIVAVFTRGMLQRLLILVGLIVACALYALLANGLGLGKPLDFSPLAQAAWFGLPHFT
TPSFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYIGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAALIAMLLGFSPKFGALIHTIPGPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNSNLIMVSVTLVLGAGDFA
LSLGGFTLGGIGTATFGAILLHALLHRGTREAKEARVTPV
>Mature_439_residues
ALFDFPRWKLTSPAAESGVVAPDERLSAGQTLVMGVQHAVAMFGATVLMPLLMGLDPNLSILMSGVGTLLFFVVTGGRVP
SYLGSSAAFVGVVIAITGFNGQGLNPHLSVALGGIIACGLVYTLIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPI
AVRSVSASAFDSWMAVLTVLCIGIVAVFTRGMLQRLLILVGLIVACALYALLANGLGLGKPLDFSPLAQAAWFGLPHFTT
PSFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYIGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYS
TLVFVAAALIAMLLGFSPKFGALIHTIPGPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNSNLIMVSVTLVLGAGDFAL
SLGGFTLGGIGTATFGAILLHALLHRGTREAKEARVTPV

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=427, Percent_Identity=88.2903981264637, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI1788843, Length=402, Percent_Identity=37.5621890547264, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI87082181, Length=465, Percent_Identity=25.8064516129032, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87082178, Length=407, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790087, Length=407, Percent_Identity=25.3071253071253, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71993493, Length=182, Percent_Identity=32.967032967033, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=182, Percent_Identity=32.967032967033, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542262, Length=172, Percent_Identity=31.3953488372093, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17558856, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17541904, Length=174, Percent_Identity=30.4597701149425, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356175, Length=171, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45250; Mature: 45119

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCHHHHHCCCCCC
>Mature Secondary Structure 
ALFDFPRWKLTSPAAESGVVAPDERLSAGQTLVMGVQHAVAMFGATVLMPLLMGLDPNL
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SILMSGVGTLLFFVVTGGRVPSYLGSSAAFVGVVIAITGFNGQGLNPHLSVALGGIIACG
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHH
LVYTLIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVRSVSASAFDSWMAVLTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LCIGIVAVFTRGMLQRLLILVGLIVACALYALLANGLGLGKPLDFSPLAQAAWFGLPHFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCC
TPSFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYIGRAFVGDGLATMLSGSVG
CCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHCCCCC
GSGVTTYAENIGVMAVTKVYSTLVFVAAALIAMLLGFSPKFGALIHTIPGPVIGGASIVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHH
FGLIAVAGARIWVQNRVDLSQNSNLIMVSVTLVLGAGDFALSLGGFTLGGIGTATFGAIL
HHHHHHHHHHHEEECCCCCCCCCCEEEEEEEEHHCCCHHHEEECCEEECCHHHHHHHHHH
LHALLHRGTREAKEARVTPV
HHHHHHCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]