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The map label for this gene is pncB [H]

Identifier: 238893993

GI number: 238893993

Start: 1888587

End: 1889789

Strand: Reverse

Name: pncB [H]

Synonym: KP1_1937

Alternate gene names: 238893993

Gene position: 1889789-1888587 (Counterclockwise)

Preceding gene: 238893996

Following gene: 238893988

Centisome position: 36.01

GC content: 58.94

Gene sequence:

>1203_bases
ATGACACAATTCACTTCTCCTGTACTGCACTCGCTGCTTGATACGGATGCCTATAAGCTGCACATGCAGCAGGCTGTCTT
CCACCGCTACGGCGATGTGCATGTGGCGGCGGAGTTTCGCTGCCGCGGAGACGACCTGCTCGGCATCTATGCCGACGCGA
TCCGCGAGCAGGTGGAGTCCATGCGCGACCTGAGGCTGCGGGATGATGAATATCGCTGGCTGTCCACCCTTCCCTTTTTT
CGCCAGGATTACCTCAACTGGCTGCGCGATTTTCGCTATGACCCGAGCCAGGTCACGGTCAGCAATGACAATGGTAAGCT
GAACATTCGCCTTACCGGCCCATGGCGGGAAGCCATCATGTGGGAAGTCCCGCTGCTGGCGGTGATAAGCGAGTTGGTCC
ATCGCTATCGTTCACCAGAGATGGGCGTCGATCAGGCGCTCAACACGCTGGAACATAAGCTAGGCGACTTCGCCACCATG
ACCGCTGACCTCGACATGAGCGCCTTCCGTCTGATGGACTTCGGCACCCGCCGTCGTTTCTCACGCGAGGTGCAGGAAGG
TATTGTGCGGCGTCTGCAGCAGGAACCATGGTTTGTCGGCACCAGCAATTACGATCTGGCGCGCCGTCTGAATTTAACCC
CGATGGGTACCCAGGCCCATGAGTGGTTCCAGGCCCACCAGCAGATCAGCCCGAGCCTTGCCAGCAGCCAGCGGGCGGCC
CTTGCCGCCTGGCTGGAAGAGTATCCCGACCAGCTGGGTATCGCGCTGACCGACTGCATCACTATGGATGCGTTCCTGCG
CGATTTCGGTCCGGAATTCGCCACCCGCTATCAGGGGTTGCGCCACGATTCCGGCGACCCGGTGGAATGGGGAGAAAAAG
CTATCGCCCATTATCAGAAGCTGGGTATCGATCCGCTGAGCAAAGTGCTGGTCTTCTCCGATAATCTCGACCTGGCGAAA
GCCGTCGATCTGTATCGCCACTTCGCCTCGCGGGTGAAGCTCAGCTTTGGGATCGGCACCCGTTTAACCTGCGATCTGCC
GCAGGTTAAACCGCTCAATATCGTGATTAAGCTGGTGGAATGTAACGGCAAGCCGGTGGCGAAACTCTCCGACAGCCCGG
GGAAAACCATCTGCCACGATAAGGCCTTCGTCCGCGCCCTGCGCGAAGCGTTCGACCTGCCGCCGATTAAAAAGGCAAGC
TAA

Upstream 100 bases:

>100_bases
GCCATCGCGGGACAGAGTCGGGTAATAAAGGTATACTCCGCCTCCATTTTCCGCGTTGGTTTCGATGGAACGCTCCAGTG
AGAGGATGCTACTGCGCACC

Downstream 100 bases:

>100_bases
AAAACTTGGCCCGACGGCATTCTGCTATCGGGCCAATCAATATCACTCCTGCGGCAGACGGGTTCTGACGACCTCGGCAA
AATACTCCGCGCCAGTTAGC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQFTSPVLHSLLDTDAYKLHMQQAVFHRYGDVHVAAEFRCRGDDLLGIYADAIREQVESMRDLRLRDDEYRWLSTLPFF
RQDYLNWLRDFRYDPSQVTVSNDNGKLNIRLTGPWREAIMWEVPLLAVISELVHRYRSPEMGVDQALNTLEHKLGDFATM
TADLDMSAFRLMDFGTRRRFSREVQEGIVRRLQQEPWFVGTSNYDLARRLNLTPMGTQAHEWFQAHQQISPSLASSQRAA
LAAWLEEYPDQLGIALTDCITMDAFLRDFGPEFATRYQGLRHDSGDPVEWGEKAIAHYQKLGIDPLSKVLVFSDNLDLAK
AVDLYRHFASRVKLSFGIGTRLTCDLPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALREAFDLPPIKKAS

Sequences:

>Translated_400_residues
MTQFTSPVLHSLLDTDAYKLHMQQAVFHRYGDVHVAAEFRCRGDDLLGIYADAIREQVESMRDLRLRDDEYRWLSTLPFF
RQDYLNWLRDFRYDPSQVTVSNDNGKLNIRLTGPWREAIMWEVPLLAVISELVHRYRSPEMGVDQALNTLEHKLGDFATM
TADLDMSAFRLMDFGTRRRFSREVQEGIVRRLQQEPWFVGTSNYDLARRLNLTPMGTQAHEWFQAHQQISPSLASSQRAA
LAAWLEEYPDQLGIALTDCITMDAFLRDFGPEFATRYQGLRHDSGDPVEWGEKAIAHYQKLGIDPLSKVLVFSDNLDLAK
AVDLYRHFASRVKLSFGIGTRLTCDLPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALREAFDLPPIKKAS
>Mature_399_residues
TQFTSPVLHSLLDTDAYKLHMQQAVFHRYGDVHVAAEFRCRGDDLLGIYADAIREQVESMRDLRLRDDEYRWLSTLPFFR
QDYLNWLRDFRYDPSQVTVSNDNGKLNIRLTGPWREAIMWEVPLLAVISELVHRYRSPEMGVDQALNTLEHKLGDFATMT
ADLDMSAFRLMDFGTRRRFSREVQEGIVRRLQQEPWFVGTSNYDLARRLNLTPMGTQAHEWFQAHQQISPSLASSQRAAL
AAWLEEYPDQLGIALTDCITMDAFLRDFGPEFATRYQGLRHDSGDPVEWGEKAIAHYQKLGIDPLSKVLVFSDNLDLAKA
VDLYRHFASRVKLSFGIGTRLTCDLPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALREAFDLPPIKKAS

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=400, Percent_Identity=87, Blast_Score=733, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324783, Length=419, Percent_Identity=33.6515513126492, Blast_Score=214, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45865; Mature: 45734

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFTSPVLHSLLDTDAYKLHMQQAVFHRYGDVHVAAEFRCRGDDLLGIYADAIREQVES
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
MRDLRLRDDEYRWLSTLPFFRQDYLNWLRDFRYDPSQVTVSNDNGKLNIRLTGPWREAIM
HHHCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCHHHHHH
WEVPLLAVISELVHRYRSPEMGVDQALNTLEHKLGDFATMTADLDMSAFRLMDFGTRRRF
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHHHH
SREVQEGIVRRLQQEPWFVGTSNYDLARRLNLTPMGTQAHEWFQAHQQISPSLASSQRAA
HHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
LAAWLEEYPDQLGIALTDCITMDAFLRDFGPEFATRYQGLRHDSGDPVEWGEKAIAHYQK
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LGIDPLSKVLVFSDNLDLAKAVDLYRHFASRVKLSFGIGTRLTCDLPQVKPLNIVIKLVE
HCCCHHHHHEEECCCCCHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALREAFDLPPIKKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQFTSPVLHSLLDTDAYKLHMQQAVFHRYGDVHVAAEFRCRGDDLLGIYADAIREQVES
CCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
MRDLRLRDDEYRWLSTLPFFRQDYLNWLRDFRYDPSQVTVSNDNGKLNIRLTGPWREAIM
HHHCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCHHHHHH
WEVPLLAVISELVHRYRSPEMGVDQALNTLEHKLGDFATMTADLDMSAFRLMDFGTRRRF
HHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHHHH
SREVQEGIVRRLQQEPWFVGTSNYDLARRLNLTPMGTQAHEWFQAHQQISPSLASSQRAA
HHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
LAAWLEEYPDQLGIALTDCITMDAFLRDFGPEFATRYQGLRHDSGDPVEWGEKAIAHYQK
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LGIDPLSKVLVFSDNLDLAKAVDLYRHFASRVKLSFGIGTRLTCDLPQVKPLNIVIKLVE
HCCCHHHHHEEECCCCCHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALREAFDLPPIKKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA