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The map label for this gene is mukE [H]

Identifier: 238893979

GI number: 238893979

Start: 1869321

End: 1870052

Strand: Direct

Name: mukE [H]

Synonym: KP1_1923

Alternate gene names: 238893979

Gene position: 1869321-1870052 (Clockwise)

Preceding gene: 238893978

Following gene: 238893980

Centisome position: 35.62

GC content: 56.83

Gene sequence:

>732_bases
ATGATTACGGAGCCAAGGTACAGGCGCATGTCATTGACAAATATTGAACAAGTGATGCCGGTTAAGCTGGCGCAGGCGTT
GGCCAATCCGTTATTTCCGGCGCTGGACAGCGCCCTGCGCGCGGGCCGTCATATCGGTCTCGACGAGCTGGATAATCACG
CATTTTTGATGGATTTTCAGGATTACCTGGAAGAGTTTTACGCTCGCTATAACGTCGAGCTGATCCGCGCGCCGGAGGGA
TTCTTCTACCTGCGCCCGCGGTCCACCACGCTGATTTCGCGCTCGGTACTGTCCGAGCTGGATATGATGGTGGGCAAAAT
TCTTTGCTATCTCTATCTCAGCCCGGAGCGCCTGGCGAACGAAGGGATTTTTACCCAGCAGGAGCTCTATGACGAGCTGC
TGACCCTGGCCGATGAATCCAGGCTGCTGAAGCTGGTGAACAACCGTTCCACCGGTTCGGATCTGGACCGCCAGAAGCTG
CAGGAAAAAATGCGGGCCTCGCTTAACCGCTTACGCCGTCTGGGGATGGTGTGGTTTATGGGCCACGATAGCAGCAAGTT
TCGCATTACCGAATCGGTATTCCGCTTTGGCGCCGATGTGCGCGCCGGCGACGACCCGCGCGAAGCGCAGCGCCGTCTGA
TCCGCGACGGGGAAGCGATGGCCCTGGAAAATCACCTGCAGCTCAATGATGAGAATGAAGAAAACCAGCCGGATAGCGGG
GAGGAAGAGTAA

Upstream 100 bases:

>100_bases
CGTCACTTCGACGTGGCGCGGATCGTCGTGGATCAGGCGGTACAGCTGGGCGTCGCCCAGGCAGATTTCACCGGACTGCC
GGCAAAATGGCAGCCGATTA

Downstream 100 bases:

>100_bases
TGATTGAACGCGGTAAGTTTCGCTCGCTAACGCTGGTTAACTGGAACGGCTTCTTTGCCCGGACCTTTGATCTTGATGAA
CTGGTGACCACCCTCTCCGG

Product: condesin subunit E

Products: NA

Alternate protein names: Protein kicA [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MITEPRYRRMSLTNIEQVMPVKLAQALANPLFPALDSALRAGRHIGLDELDNHAFLMDFQDYLEEFYARYNVELIRAPEG
FFYLRPRSTTLISRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADESRLLKLVNNRSTGSDLDRQKL
QEKMRASLNRLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMALENHLQLNDENEENQPDSG
EEE

Sequences:

>Translated_243_residues
MITEPRYRRMSLTNIEQVMPVKLAQALANPLFPALDSALRAGRHIGLDELDNHAFLMDFQDYLEEFYARYNVELIRAPEG
FFYLRPRSTTLISRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADESRLLKLVNNRSTGSDLDRQKL
QEKMRASLNRLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMALENHLQLNDENEENQPDSG
EEE
>Mature_243_residues
MITEPRYRRMSLTNIEQVMPVKLAQALANPLFPALDSALRAGRHIGLDELDNHAFLMDFQDYLEEFYARYNVELIRAPEG
FFYLRPRSTTLISRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADESRLLKLVNNRSTGSDLDRQKL
QEKMRASLNRLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMALENHLQLNDENEENQPDSG
EEE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=234, Percent_Identity=94.8717948717949, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 28225; Mature: 28225

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITEPRYRRMSLTNIEQVMPVKLAQALANPLFPALDSALRAGRHIGLDELDNHAFLMDFQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCEEEECHH
DYLEEFYARYNVELIRAPEGFFYLRPRSTTLISRSVLSELDMMVGKILCYLYLSPERLAN
HHHHHHHHHHCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
EGIFTQQELYDELLTLADESRLLKLVNNRSTGSDLDRQKLQEKMRASLNRLRRLGMVWFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEE
GHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMALENHLQLNDENEENQPDSG
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
EEE
CCC
>Mature Secondary Structure
MITEPRYRRMSLTNIEQVMPVKLAQALANPLFPALDSALRAGRHIGLDELDNHAFLMDFQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCEEEECHH
DYLEEFYARYNVELIRAPEGFFYLRPRSTTLISRSVLSELDMMVGKILCYLYLSPERLAN
HHHHHHHHHHCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
EGIFTQQELYDELLTLADESRLLKLVNNRSTGSDLDRQKLQEKMRASLNRLRRLGMVWFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEE
GHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMALENHLQLNDENEENQPDSG
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
EEE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7513784; 8905232; 9278503; 1989883; 8602138 [H]