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The map label for this gene is mukF [H]

Identifier: 238893978

GI number: 238893978

Start: 1868045

End: 1869367

Strand: Direct

Name: mukF [H]

Synonym: KP1_1922

Alternate gene names: 238893978

Gene position: 1868045-1869367 (Clockwise)

Preceding gene: 238893977

Following gene: 238893979

Centisome position: 35.59

GC content: 57.37

Gene sequence:

>1323_bases
ATGAGTGAATTTTCCCAGACAGTCCCCGAACTGGTTGCCTGGGCCAGAAAAAATGATTTTTCAATCTCGCTACCGGTCGA
CAGACTCTCTTTCCTGCTGGCGATCGCCACTCTGAATGGTGAACGACTGGAAGGGGAAATGAGCGAGGGTGAACTGGTGG
ATGCGTTCCGCCACGTCAGTGATGCGTTTGAGCAGACCAGCGAAACCATCAGCCAGCGCGCCAATAACGCGATCAACGAT
TTGGTGCGCCAGCGTCTGCTGAACCGCTTTACCAGCGAAATTACCGAAGGCAATGCGATCTATCGCCTGACGCCGTTGGG
GATTGGGATCACCGATTATTATATCCGACAGCGCGAATTCTCGACGCTGCGTCTCTCGATGCAGCTGTCGATCGTTGCCG
GCGAGCTGAAGCGCGCGGCGGATGCCGCGGAAGAGGGCGGTGATGAATTCCACTGGCATCGCAACGTTTTTGCGCCGCTG
AAGTACTCCGTAGCGGAAATTTTCGACAGCATCGACCTGACGCAGCGCATTATGGATGAGCAGCAGCAGCTGGTGAAAGA
CGATATCGCGCAGTTGTTGAATAAAGACTGGCGCGCGGCGATTTCCAGCTGTGAACTGCTGCTGTCGGAAACCTCCGGCA
CCCTGCGCGAACTGCAGGATACGCTGGATGCGGCAGGGGATAAGCTGCAGGCGAACCTGCTGCGCATTCAGGACTCGACC
ATGGCGCGCGACGATCTCCATTTTGTCGATCGGCTGGTGTTCGATCTGCAAAGCAAGCTCGACCGCATCGTCAGCTGGGG
TCAGCAGGCGATTGACCTGTGGATCGGCTACGACCGCCATGTGCACAAGTTTATCCGTACCGCTATCGATATGGATAAGA
ACCGCGTCTTCGCCCAGCGTCTGCGCCAGTCGGTGCAGACCTATTTTGATGAACCGTGGGCGCTAACTTACGCCAACGCC
GACCGCCTGCTGGATATGCGCGATGAAGAGATGGCCCTGCGCGATGAAGAGGTCACCGGCGAGCTGCCGGCGGACCTCGA
ATTTGAAGAGTTTAACGAAATTCGCGAGCAGCTGGCGGCGCTGATCGAAGCGCAGCTGGCGGTCTATAAAGAGAAAGGAA
TACCGCTGGATCTCGGCCTGGTGGCGCGGGAGTTCCTGGCGCAGTATCCGCGCGGGCGTCACTTCGACGTGGCGCGGATC
GTCGTGGATCAGGCGGTACAGCTGGGCGTCGCCCAGGCAGATTTCACCGGACTGCCGGCAAAATGGCAGCCGATTAATGA
TTACGGAGCCAAGGTACAGGCGCATGTCATTGACAAATATTGA

Upstream 100 bases:

>100_bases
CGCGCTACTGTCGTCAGGAGCCGTATCTCAGCCTGGGCCGTTATATTCATGTCACCGCGCTTAAGAGCCAGGCTCATAGC
CGCAGATGCAAGGATAAAGT

Downstream 100 bases:

>100_bases
ACAAGTGATGCCGGTTAAGCTGGCGCAGGCGTTGGCCAATCCGTTATTTCCGGCGCTGGACAGCGCCCTGCGCGCGGGCC
GTCATATCGGTCTCGACGAG

Product: condesin subunit F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAIATLNGERLEGEMSEGELVDAFRHVSDAFEQTSETISQRANNAIND
LVRQRLLNRFTSEITEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVFAPL
KYSVAEIFDSIDLTQRIMDEQQQLVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLDAAGDKLQANLLRIQDST
MARDDLHFVDRLVFDLQSKLDRIVSWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANA
DRLLDMRDEEMALRDEEVTGELPADLEFEEFNEIREQLAALIEAQLAVYKEKGIPLDLGLVAREFLAQYPRGRHFDVARI
VVDQAVQLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY

Sequences:

>Translated_440_residues
MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAIATLNGERLEGEMSEGELVDAFRHVSDAFEQTSETISQRANNAIND
LVRQRLLNRFTSEITEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVFAPL
KYSVAEIFDSIDLTQRIMDEQQQLVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLDAAGDKLQANLLRIQDST
MARDDLHFVDRLVFDLQSKLDRIVSWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANA
DRLLDMRDEEMALRDEEVTGELPADLEFEEFNEIREQLAALIEAQLAVYKEKGIPLDLGLVAREFLAQYPRGRHFDVARI
VVDQAVQLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
>Mature_439_residues
SEFSQTVPELVAWARKNDFSISLPVDRLSFLLAIATLNGERLEGEMSEGELVDAFRHVSDAFEQTSETISQRANNAINDL
VRQRLLNRFTSEITEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVFAPLK
YSVAEIFDSIDLTQRIMDEQQQLVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLDAAGDKLQANLLRIQDSTM
ARDDLHFVDRLVFDLQSKLDRIVSWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANAD
RLLDMRDEEMALRDEEVTGELPADLEFEEFNEIREQLAALIEAQLAVYKEKGIPLDLGLVAREFLAQYPRGRHFDVARIV
VDQAVQLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid

COG id: COG3006

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukF family [H]

Homologues:

Organism=Escherichia coli, GI1787152, Length=440, Percent_Identity=93.1818181818182, Blast_Score=848, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005582 [H]

Pfam domain/function: PF03882 KicB [H]

EC number: NA

Molecular weight: Translated: 50288; Mature: 50157

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAIATLNGERLEGEMSEGELVDAFRHVS
CCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHH
DAFEQTSETISQRANNAINDLVRQRLLNRFTSEITEGNAIYRLTPLGIGITDYYIRQREF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHH
STLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVFAPLKYSVAEIFDSIDLTQRIMDE
HHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QQQLVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLDAAGDKLQANLLRIQDST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCH
MARDDLHFVDRLVFDLQSKLDRIVSWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
LRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPADLEFEEFNEIREQLAA
HHHHHHHHHCCCCEEEECCHHHHHCCCCHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHH
LIEAQLAVYKEKGIPLDLGLVAREFLAQYPRGRHFDVARIVVDQAVQLGVAQADFTGLPA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCCC
KWQPINDYGAKVQAHVIDKY
CCCCCCHHCCEEEEEECCCC
>Mature Secondary Structure 
SEFSQTVPELVAWARKNDFSISLPVDRLSFLLAIATLNGERLEGEMSEGELVDAFRHVS
CHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHH
DAFEQTSETISQRANNAINDLVRQRLLNRFTSEITEGNAIYRLTPLGIGITDYYIRQREF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHH
STLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVFAPLKYSVAEIFDSIDLTQRIMDE
HHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QQQLVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLDAAGDKLQANLLRIQDST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCH
MARDDLHFVDRLVFDLQSKLDRIVSWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
LRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPADLEFEEFNEIREQLAA
HHHHHHHHHCCCCEEEECCHHHHHCCCCHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHH
LIEAQLAVYKEKGIPLDLGLVAREFLAQYPRGRHFDVARIVVDQAVQLGVAQADFTGLPA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCCC
KWQPINDYGAKVQAHVIDKY
CCCCCCHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA