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The map label for this gene is kdsB [H]

Identifier: 238893974

GI number: 238893974

Start: 1864594

End: 1865340

Strand: Direct

Name: kdsB [H]

Synonym: KP1_1918

Alternate gene names: 238893974

Gene position: 1864594-1865340 (Clockwise)

Preceding gene: 238893973

Following gene: 238893975

Centisome position: 35.53

GC content: 61.31

Gene sequence:

>747_bases
ATGAGTTTCGTGGTCATTATTCCTGCGCGTTTCGCCTCCACGCGCCTGCCGGGAAAACCACTGCAGGACATTAATGGTAA
GCCGATGATTGTCCATGTGCTGGAGCGCGCTCGCGAATCCGGCGCGGATCGCATTATTGTCGCCACCGATCACGAAGATG
TCGCCCGGGCGGTTGAAGCCGCCGGCGGCGAGGTCTGTATGACCCGCGCCGACCATCAGTCCGGCACCGAACGGCTGGCG
GAAGTGGTGGAAAAGTGTGCGTTCAGCGATGACACCATTATCGTCAATATTCAGGGCGATGAGCCGATGATCCCCCCGGC
GATTGTCCGCCAGGTGGCGGAGAATCTGGCTGCCAGCAGCAGCGGAATGGCGACCCTGGCGGTACCGATCCATGATGCGG
AAGAGGCGTTTAACCCGAATGCGGTCAAAGTGGTGATGGATGCCGAGGGTTACGCGCTCTATTTCTCCCGCGCGACTATT
CCCTGGGATCGCGATCGCTTTGCCCAATCCCGCGAGACCATCGGTGACTCCCTGCTGCGTCACATCGGCATCTATGGCTA
TCGCGCCGGCTTTATCCGCCGCTATGTCAGCTGGGCGCCGAGCCCGCTGGAGCAGATTGAAATGCTCGAGCAGCTGCGAG
TGCTGTGGTATGGCGAGAAAATCCATGTCGCCGTGGCGGCGGAAGTGCCCGGCACCGGCGTGGATACCCCGGAAGATCTG
GAGCGCGTCCGCGCTGAGCTGCGTTAG

Upstream 100 bases:

>100_bases
TTATTTGCAAACTTGATAGCCTGGCGTTTCCGCTGCGCGACGGTATCCCGGTGCTGCTGGAGACAGAGGCGCGTCCGCTG
GCGCTAGAAGAGAGTCACTC

Downstream 100 bases:

>100_bases
TCCTCTGTCCCCTCCTTGCTGGAGGGGATATCCCGTCGGTTTTTCGCTTTTTTTACCCCTTTTTGATCTTATCCGATGAC
AAGCCAGGTGCGGGCGCTCA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAEGYALYFSRATI
PWDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
ERVRAELR

Sequences:

>Translated_248_residues
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAEGYALYFSRATI
PWDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
ERVRAELR
>Mature_247_residues
SFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAE
VVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAEGYALYFSRATIP
WDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDLE
RVRAELR

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=248, Percent_Identity=89.1129032258064, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27334; Mature: 27203

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEA
CCEEEEECCCHHCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
AGGEVCMTRADHQSGTERLAEVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASS
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
SGMATLAVPIHDAEEAFNPNAVKVVMDAEGYALYFSRATIPWDRDRFAQSRETIGDSLLR
CCCEEEEEEECCHHHHCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCEEEEEEEEECCCCCCCCHHHH
ERVRAELR
HHHHHHCC
>Mature Secondary Structure 
SFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEA
CEEEEECCCHHCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
AGGEVCMTRADHQSGTERLAEVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASS
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
SGMATLAVPIHDAEEAFNPNAVKVVMDAEGYALYFSRATIPWDRDRFAQSRETIGDSLLR
CCCEEEEEEECCHHHHCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCEEEEEEEEECCCCCCCCHHHH
ERVRAELR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA