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The map label for this gene is gudP [H]

Identifier: 238893849

GI number: 238893849

Start: 1719745

End: 1721076

Strand: Direct

Name: gudP [H]

Synonym: KP1_1781

Alternate gene names: 238893849

Gene position: 1719745-1721076 (Clockwise)

Preceding gene: 238893848

Following gene: 238893850

Centisome position: 32.77

GC content: 50.83

Gene sequence:

>1332_bases
ATGTCACGTATAGATACGCTGGTCTGTACTGACGCCAGGAAAACGAAATATCGTTTCGTGGTTTTGACGATGATTTTTCT
GGTGTATGCCATCAATTACGCCGACCGAACGAATATTGGCGCGGTACTGCCTTTCATCATTGATGAGTTTCATATCAATA
ATTTTGAAGCCGGGGCCATCGCCAGTATGTTTTTCCTCGGCTATGCGGTAAGCCAGATCCCGGCCGGCTTTTTCATCGCC
AAACGCGGTACCCGGGGGCTGGTATCGCTCTCCATTTTCGGCTTCTCCGCCTTTACCTGGCTGATGGGCACGGTGAGCTC
CGTGTTTGGCCTGAAGCTGGTGCGGCTGGGACTGGGGCTGAGCGAAGGGCCTTGCCCGGTGGGGCTGGCTTCCACCATAA
ATAACTGGTTTCCACCAAAGGAGAAAGCCACGGCAACCGGCGTTTACATCGCGGCGACCATGTTTGCGCCGATTATTGTG
CCGCCGCTGGCGGTGTGGATTGCGGTGACCTGGGGGGGGCGGTGGGTCTTTTTCTCTTTTGCTATACCCGGAATTGTGGC
GGCCATCGCGTGGTATCTGCTGGTCAAATCCAAGCCTGCTGAGAGCGGATTTGTTTCCCAAAGCGAACTGGCAGAGATTA
ATGCCGGGCGTGAAAGTCATAATAATAGCGTACGCGAAAATATATTAATTGCCGATCGATTCACCTGGCTGGATAAAATC
ATTCGGGTAAAGAAAATGGCGCCAATTGATACGGCGAAAGGCTTATTCACCTCAAAAAATATTCTCGGTGACTGCCTGGC
GTATTTTATGATGGTTAGCGTGCTGTACGGATTATTAACCTGGATCCCCCTGTATTTAGTCAAAGAGCGTGGCTTTGATG
TAATGAGTATGGGCTTCGTGGCCAGTATGCCGTGCATCGGCGGCTTTATTGGCGCGATTGGCGGCGGGTGGATTTCAGAT
AAAGTCCTGGGCCGCCGACGTAAACCCACCATGATGTTCACTGCCGTGTCAACGGTGGTCATGATGTTAATTATGCTGAA
TATCCCGGCCAGCACCCTGGCGGTCTGTATTGGATTATTTTTTGTCGGCTTTTGTTTAAATATCGGCTGGCCAGCCTTTA
CCGCGTACGGCATGGCCGTTTCGGATAGCAAAACCTATCCAATCGCCTCTTCCATAATTAATAGCGGCGGCAACCTCGGT
GGATTTGTCGCGCCGATGGCGGCTGGTTTCTTGCTTGATAAAACCGGGAGTTTTAATTCTGTATTTACCTATTTTGGTAT
CTGCGCCGCCATTGGTTTGGTGGTGATTCTTTTCCTCGATGAACCACAATAA

Upstream 100 bases:

>100_bases
GAAAAGCATTTATCTCTTGCTCCTGTATGGATAGTAAAACGCGGTGATCCGAAGCGGCAGCTTACAGCGAAGTGGATGAG
GTATAAAACGAGGAAACCCT

Downstream 100 bases:

>100_bases
CGGAAATATATCCTGTTAATTAATATGACGTAATGTCATGGAGTGAAACTATGTTATTAAAAGATAAAGTCGCCATTATT
ACTGGCGCGGCCTCCGCACG

Product: putative general substrate transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAIASMFFLGYAVSQIPAGFFIA
KRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGLSEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIV
PPLAVWIAVTWGGRWVFFSFAIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIADRFTWLDKI
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFVASMPCIGGFIGAIGGGWISD
KVLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLFFVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLG
GFVAPMAAGFLLDKTGSFNSVFTYFGICAAIGLVVILFLDEPQ

Sequences:

>Translated_443_residues
MSRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAIASMFFLGYAVSQIPAGFFIA
KRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGLSEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIV
PPLAVWIAVTWGGRWVFFSFAIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIADRFTWLDKI
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFVASMPCIGGFIGAIGGGWISD
KVLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLFFVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLG
GFVAPMAAGFLLDKTGSFNSVFTYFGICAAIGLVVILFLDEPQ
>Mature_442_residues
SRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAIASMFFLGYAVSQIPAGFFIAK
RGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGLSEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIVP
PLAVWIAVTWGGRWVFFSFAIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIADRFTWLDKII
RVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFVASMPCIGGFIGAIGGGWISDK
VLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLFFVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLGG
FVAPMAAGFLLDKTGSFNSVFTYFGICAAIGLVVILFLDEPQ

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=289, Percent_Identity=24.5674740484429, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI9945322, Length=418, Percent_Identity=23.444976076555, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI148743791, Length=385, Percent_Identity=20.7792207792208, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI9966811, Length=420, Percent_Identity=23.0952380952381, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789152, Length=453, Percent_Identity=28.2560706401766, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1789515, Length=454, Percent_Identity=27.9735682819383, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI87082320, Length=437, Percent_Identity=26.5446224256293, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI2367379, Length=444, Percent_Identity=26.8018018018018, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI2367193, Length=308, Percent_Identity=23.7012987012987, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87082310, Length=369, Percent_Identity=21.680216802168, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=340, Percent_Identity=24.7058823529412, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=333, Percent_Identity=24.6246246246246, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560030, Length=326, Percent_Identity=24.8466257668712, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17552542, Length=329, Percent_Identity=24.9240121580547, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=411, Percent_Identity=24.330900243309, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=411, Percent_Identity=24.330900243309, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997452, Length=442, Percent_Identity=22.1719457013575, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=297, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639764, Length=455, Percent_Identity=24.8351648351648, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641682, Length=406, Percent_Identity=23.8916256157635, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24654215, Length=458, Percent_Identity=22.9257641921397, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19922400, Length=445, Percent_Identity=23.3707865168539, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648416, Length=452, Percent_Identity=22.1238938053097, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356189, Length=452, Percent_Identity=22.1238938053097, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573708, Length=444, Percent_Identity=21.1711711711712, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573707, Length=444, Percent_Identity=21.1711711711712, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20130167, Length=459, Percent_Identity=23.3115468409586, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48011; Mature: 47880

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAI
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
ASMFFLGYAVSQIPAGFFIAKRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGL
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIVPPLAVWIAVTWGGRWVFFSF
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEHH
AIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIADRFTWLDKI
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHCCCHHHHHEEEHHHHHHHHHH
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFV
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ASMPCIGGFIGAIGGGWISDKVLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLF
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLGGFVAPMAAGFLLDKTGSFNS
HHHHHHHCCCHHHHHHCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCHH
VFTYFGICAAIGLVVILFLDEPQ
HHHHHHHHHHHHHHEEHEECCCC
>Mature Secondary Structure 
SRIDTLVCTDARKTKYRFVVLTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAI
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
ASMFFLGYAVSQIPAGFFIAKRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGL
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEGPCPVGLASTINNWFPPKEKATATGVYIAATMFAPIIVPPLAVWIAVTWGGRWVFFSF
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEHH
AIPGIVAAIAWYLLVKSKPAESGFVSQSELAEINAGRESHNNSVRENILIADRFTWLDKI
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHCCCHHHHHEEEHHHHHHHHHH
IRVKKMAPIDTAKGLFTSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFV
HHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ASMPCIGGFIGAIGGGWISDKVLGRRRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLF
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FVGFCLNIGWPAFTAYGMAVSDSKTYPIASSIINSGGNLGGFVAPMAAGFLLDKTGSFNS
HHHHHHHCCCHHHHHHCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCHH
VFTYFGICAAIGLVVILFLDEPQ
HHHHHHHHHHHHHHEEHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]