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The map label for this gene is perR [H]

Identifier: 238893847

GI number: 238893847

Start: 1718405

End: 1719328

Strand: Reverse

Name: perR [H]

Synonym: KP1_1779

Alternate gene names: 238893847

Gene position: 1719328-1718405 (Counterclockwise)

Preceding gene: 238893856

Following gene: 238893846

Centisome position: 32.76

GC content: 54.98

Gene sequence:

>924_bases
ATGAGCCAACCGCTACCCAATAAAAATCTGCCGATGCCCTCTTTACGCAATATCCAGGCTTTTATTGAAGTCGCCGCTAC
CGGCAGCCTTAATCTGGCCGCAGAGAATCTCAATATTACCGCCTCGGCGGTCAGCCATCAGATAGCCAGCCTGGAGCACT
TTCTGGGGAAAAAACTGTTCTCCCGCAGCAGCAAAGGCGTCACGTTAACGGCGGTGGGAGAAAAATATCTCAAAGAGGTC
TCCGGGGCGCTGAATATGATTGGCCAGGCCACCAGCCAGGTGATCAACGATATCCATCAGGATTATTTACGCATTCATTC
GGCGCCGAGCTTCGGCCTGCTATGGCTGATGCCCCGTCTGGATAAATTCCGCCAGGCGTGGCCGGCGTTAAAAATCAGCC
TGACCTGTTCATACGAAAGCATCCAGTTCTCCCGGGATAATATTGATATCGATATTCGTCACGGGCTGTCACAGTGGCCG
ACGCTGCTGGTCAGAACCATTAAAAATGAGCGCGTCCTGCCCTACAGCGCAGCGTCTTATTTAGCCAGCCATCCTGTGCA
GGCTGTGGAAGATCTGCTGGCCTGCGATCTGATCCACTCCGACAGCACCTTGATTAACTGGAGCAACTGGCTGTCGTGGC
ACAAGGTCCGCGGCTGGCATAAAAACTTCATTTTTAATTTCGACCGGTCATATATGAGCATCGAGGCGGCCAGAATGGGG
ATGGGCGTGATCCTCGAGAGCAATCTGCTGGCCGGCGGACACGTGCGCCAGGGACAGCTGACGCCGGTATTTGCCGACGA
GCGGAGCATGCCGGTCGGCGCGCACCACTTCGTCCTCCCCCACGCTAATGAACAGAAGGAGAAGGTCCAGCGCTTCTTCG
CCTGGGTCGCCGGAGAGCTGAAAGAGGAAGGGTTCCATATTTGA

Upstream 100 bases:

>100_bases
AAATTAACGTTGTTTTTTCGCTTTTCCCTATGCTGTACATCCCGGCTGCGCCACGCTGTTCGCTATTTTCTTTTATTCGC
GCCCCGCGCAGGATGCCGCC

Downstream 100 bases:

>100_bases
TCCCGGCTGGTGGACAAACCGCCAGTCGGCGCCTAAAGTTAATCAATCGATTGATTAACTTTTACCGAGCGCGATGACCA
GTAAAGGCGAACAGGCAAAA

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: Peroxide resistance protein perR [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSQPLPNKNLPMPSLRNIQAFIEVAATGSLNLAAENLNITASAVSHQIASLEHFLGKKLFSRSSKGVTLTAVGEKYLKEV
SGALNMIGQATSQVINDIHQDYLRIHSAPSFGLLWLMPRLDKFRQAWPALKISLTCSYESIQFSRDNIDIDIRHGLSQWP
TLLVRTIKNERVLPYSAASYLASHPVQAVEDLLACDLIHSDSTLINWSNWLSWHKVRGWHKNFIFNFDRSYMSIEAARMG
MGVILESNLLAGGHVRQGQLTPVFADERSMPVGAHHFVLPHANEQKEKVQRFFAWVAGELKEEGFHI

Sequences:

>Translated_307_residues
MSQPLPNKNLPMPSLRNIQAFIEVAATGSLNLAAENLNITASAVSHQIASLEHFLGKKLFSRSSKGVTLTAVGEKYLKEV
SGALNMIGQATSQVINDIHQDYLRIHSAPSFGLLWLMPRLDKFRQAWPALKISLTCSYESIQFSRDNIDIDIRHGLSQWP
TLLVRTIKNERVLPYSAASYLASHPVQAVEDLLACDLIHSDSTLINWSNWLSWHKVRGWHKNFIFNFDRSYMSIEAARMG
MGVILESNLLAGGHVRQGQLTPVFADERSMPVGAHHFVLPHANEQKEKVQRFFAWVAGELKEEGFHI
>Mature_306_residues
SQPLPNKNLPMPSLRNIQAFIEVAATGSLNLAAENLNITASAVSHQIASLEHFLGKKLFSRSSKGVTLTAVGEKYLKEVS
GALNMIGQATSQVINDIHQDYLRIHSAPSFGLLWLMPRLDKFRQAWPALKISLTCSYESIQFSRDNIDIDIRHGLSQWPT
LLVRTIKNERVLPYSAASYLASHPVQAVEDLLACDLIHSDSTLINWSNWLSWHKVRGWHKNFIFNFDRSYMSIEAARMGM
GVILESNLLAGGHVRQGQLTPVFADERSMPVGAHHFVLPHANEQKEKVQRFFAWVAGELKEEGFHI

Specific function: Apparent regulatory gene involved in peroxide resistance in stationary phase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786448, Length=284, Percent_Identity=33.4507042253521, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789173, Length=298, Percent_Identity=30.5369127516779, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=27.027027027027, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693193, Length=303, Percent_Identity=25.4125412541254, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786401, Length=269, Percent_Identity=26.3940520446097, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI157672245, Length=206, Percent_Identity=28.1553398058252, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789440, Length=181, Percent_Identity=28.1767955801105, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790011, Length=262, Percent_Identity=22.5190839694656, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081978, Length=175, Percent_Identity=26.8571428571429, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790262, Length=169, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34508; Mature: 34377

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50931 HTH_LYSR ; PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPLPNKNLPMPSLRNIQAFIEVAATGSLNLAAENLNITASAVSHQIASLEHFLGKKLF
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHH
SRSSKGVTLTAVGEKYLKEVSGALNMIGQATSQVINDIHQDYLRIHSAPSFGLLWLMPRL
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
DKFRQAWPALKISLTCSYESIQFSRDNIDIDIRHGLSQWPTLLVRTIKNERVLPYSAASY
HHHHHHCCCEEEEEEEEEHHEEECCCCEEEEHHCCCHHHHHHHHHHHCCCCCCCHHHHHH
LASHPVQAVEDLLACDLIHSDSTLINWSNWLSWHKVRGWHKNFIFNFDRSYMSIEAARMG
HHHCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHCEEEEECCHHHHHHHHHCC
MGVILESNLLAGGHVRQGQLTPVFADERSMPVGAHHFVLPHANEQKEKVQRFFAWVAGEL
CCEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
KEEGFHI
HHCCCCC
>Mature Secondary Structure 
SQPLPNKNLPMPSLRNIQAFIEVAATGSLNLAAENLNITASAVSHQIASLEHFLGKKLF
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHH
SRSSKGVTLTAVGEKYLKEVSGALNMIGQATSQVINDIHQDYLRIHSAPSFGLLWLMPRL
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
DKFRQAWPALKISLTCSYESIQFSRDNIDIDIRHGLSQWPTLLVRTIKNERVLPYSAASY
HHHHHHCCCEEEEEEEEEHHEEECCCCEEEEHHCCCHHHHHHHHHHHCCCCCCCHHHHHH
LASHPVQAVEDLLACDLIHSDSTLINWSNWLSWHKVRGWHKNFIFNFDRSYMSIEAARMG
HHHCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHHHCEEEEECCHHHHHHHHHCC
MGVILESNLLAGGHVRQGQLTPVFADERSMPVGAHHFVLPHANEQKEKVQRFFAWVAGEL
CCEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
KEEGFHI
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]